(Q35144933)

English

Protein kinase R as mediator of the effects of interferon (IFN) gamma and tumor necrosis factor (TNF) alpha on normal and dysplastic hematopoiesis

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Protein kinase R as mediator of the effects of interferon (IFN) gamma and tumor necrosis factor (TNF) alpha on normal and dysplastic hematopoiesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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author name string

Bhumika Sharma

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Jessica K Altman

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Dennis J Goussetis

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Amit K Verma

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Leonidas C Platanias

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

9 June 2011

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

286

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

31

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

27506-27514

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Targeting immune dysregulation in myelodysplastic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Prognosis of myelodysplastic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Tumor necrosis factor receptor cross-talk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

The role of protein kinase R in the interferon response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Tumor necrosis factor-α signaling in macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Haematopoietic and stromal stem cell regulation by extracellular matrix components and growth factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

The chemokine system in experimental and clinical hematology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Mechanisms of protein kinase PKR-mediated amplification of beta interferon induction by C protein-deficient measles virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Molecular mechanisms of thrombopoietin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

MAPK signaling pathways in the regulation of hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Immune mediated autologous cytotoxicity against hematopoietic precursor cells in patients with myelodysplastic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Activation of protein kinase C{eta} by type I interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Inhibition of p38alpha MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Role of the Akt pathway in mRNA translation of interferon-stimulated genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Interferons at age 50: past, current and future impact on biomedicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Regulation of interferon-gamma during innate and adaptive immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

The protein kinase C (PKC) family of proteins in cytokine signaling in hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Protein kinase PKR plays a stimulus- and virus-dependent role in apoptotic death and virus multiplication in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Molecular basis for PKR activation by PACT or dsRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Mechanisms of type-I- and type-II-interferon-mediated signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Myelodysplastic syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Signaling pathways activated by interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Engagement of Gab1 and Gab2 in erythropoietin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

PKR--a protein kinase regulated by double-stranded RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

The PKR protein kinase--an interferon-inducible regulator of cell growth and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Immune pathophysiology of acquired aplastic anaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Interferon-α Engages the Insulin Receptor Substrate-1 to Associate with the Phosphatidylinositol 3′-Kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

The network of hemopoietic regulatory proteins in myeloid cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

28 July 2018

Mechanisms of mRNA translation of interferon stimulated genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

How cells respond to interferons revisited: from early history to current complexity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Role of the p38 mitogen-activated protein kinase pathway in cytokine-mediated hematopoietic suppression in myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Activation of protein kinase C delta by all-trans-retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Activation of protein kinase C delta by IFN-gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Regulatory effects of mammalian target of rapamycin-activated pathways in type I and II interferon signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Hematopoietic cytokine receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Proteomic identification of C/EBP-DBD multiprotein complex: JNK1 activates stem cell regulator C/EBPalpha by inhibiting its ubiquitination.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.238501

21 January 2018

Structure and function of the protein kinase R.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149343

27 September 2018

The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21659535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquired aplastic anemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21659535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21659535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of T-lymphocyte clonal dominance in patients with myelodysplastic syndrome responsive to immunosuppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21659535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21659535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aplastic anemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21659535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKR is activated in MDS patients and its subcellular localization depends on disease severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21659535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.238501

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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