(Q36557550)

14 August 2017

1 reference

title

Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase (English)

1 reference

14 August 2017

Ann M Toth

1

1 reference

14 August 2017

Ping Zhang

2

1 reference

14 August 2017

Sonali Das

3

1 reference

14 August 2017

Cyril X George

4

1 reference

14 August 2017

Charles E Samuel

5

1 reference

14 August 2017

publication date

1 January 2006

1 reference

Progress in Molecular Biology and Translational Science

14 August 2017

published in

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14 August 2017

volume

81

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14 August 2017

page(s)

369-434

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Virus interference. I. The interferon

14 August 2017

cites work

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Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

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Viruses and interferons

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7 January 2021

Interferons and their actions

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7 January 2021

Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing

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7 January 2021

Characterization of the 5'-flanking region of the human RNA-specific adenosine deaminase ADAR1 gene and identification of an interferon-inducible ADAR1 promoter

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7 January 2021

Functionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase

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7 January 2021

Genomic organization and chromosomal location of the human dsRNA adenosine deaminase gene: the enzyme for glutamate-activated ion channel RNA editing

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7 January 2021

The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2

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7 January 2021

Assignment of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization

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7 January 2021

Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis

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7 January 2021

Liver Disintegration in the Mouse Embryo Caused by Deficiency in the RNA-editing Enzyme ADAR1

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7 January 2021

Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene

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7 January 2021

Human RNA-specific adenosine deaminase (ADAR1) gene specifies transcripts that initiate from a constitutively active alternative promoter

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7 January 2021

Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible

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7 January 2021

Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase

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7 January 2021

Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing

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7 January 2021

The scanning model for translation: an update

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7 January 2021

mRNA decay: finding the right targets

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7 January 2021

Tissue selectivity of interferon-stimulated gene expression in mice infected with Dam(+) versus Dam(-) Salmonella enterica serovar Typhimurium strains

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7 January 2021

Widespread inosine-containing mRNA in lymphocytes regulated by ADAR1 in response to inflammation.

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7 January 2021

Intracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammation

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7 January 2021

Serotonin-2C receptor pre-mRNA editing in rat brain and in vitro by splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1.

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7 January 2021

Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase

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7 January 2021

Mechanism of interferon action: double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons

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7 January 2021

STATs and gene regulation

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7 January 2021

The promoter-proximal KCS element of the PKR kinase gene enhances transcription irrespective of orientation and position relative to the ISRE element and is functionally distinct from the KCS-like element of the ADAR deaminase Promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Functional analysis of the KCS-like element of the interferon-inducible RNA-specific adenosine deaminase ADAR1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Isolation of the interferon-inducible RNA-dependent protein kinase Pkr promoter and identification of a novel DNA element within the 5'-flanking region of human and mouse Pkr genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

An ADAR that edits transcripts encoding ion channel subunits functions as a dimer.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A mammalian RNA editing enzyme

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A place in the world for RNA editing

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7 January 2021

Structural Requirements for RNA Editing in Glutamate Receptor Pre-mRNAs by Recombinant Double-stranded RNA Adenosine Deaminase

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7 January 2021

Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations

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7 January 2021

Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

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7 January 2021

Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing

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7 January 2021

Mechanism of interferon action motif I of the interferon-induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activity

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7 January 2021

Proteins binding to duplexed RNA: one motif, multiple functions

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7 January 2021

Chimeric double-stranded RNA-specific adenosine deaminase ADAR1 proteins reveal functional selectivity of double-stranded RNA-binding domains from ADAR1 and protein kinase PKR.

1 reference

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7 January 2021

A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase

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7 January 2021

Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA

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7 January 2021

Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins

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7 January 2021

Left-handed Z-DNA: structure and function

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7 January 2021

A role for Z-DNA binding in vaccinia virus pathogenesis

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7 January 2021

The role of binding domains for dsRNA and Z-DNA in the in vivo editing of minimal substrates by ADAR1

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7 January 2021

Modulation of ADAR1 editing activity by Z-RNA in vitro

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The RNA-editing enzyme ADAR1 is localized to the nascent ribonucleoprotein matrix on Xenopus lampbrush chromosomes but specifically associates with an atypical loop

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

SUMO-1 modification alters ADAR1 editing activity

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7 January 2021

A developmentally regulated activity that unwinds RNA duplexes

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7 January 2021

Double-stranded RNA unwinding and modifying activity is detected ubiquitously in primary tissues and cell lines

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain.

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7 January 2021

Subcellular distribution of ADAR1 isoforms is synergistically determined by three nuclear discrimination signals and a regulatory motif

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7 January 2021

CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain

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7 January 2021

Dynamic association of RNA-editing enzymes with the nucleolus

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7 January 2021

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

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7 January 2021

Vigilins bind to promiscuously A-to-I-edited RNAs and are involved in the formation of heterochromatin.

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7 January 2021

ADAR1 interacts with NF90 through double-stranded RNA and regulates NF90-mediated gene expression independently of RNA editing

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7 January 2021

Biased (A-->I) hypermutation of animal RNA virus genomes

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7 January 2021

Biased hypermutation and other genetic changes in defective measles viruses in human brain infections

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7 January 2021

Numerous transitions in human parainfluenza virus 3 RNA recovered from persistently infected cells

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7 January 2021

Vesicular stomatitis virus defective interfering particles can contain extensive genomic sequence rearrangements and base substitutions

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7 January 2021

Mutated and hypermutated genes of persistent measles viruses which caused lethal human brain diseases

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7 January 2021

Clonal expansion of hypermutated measles virus in a SSPE brain

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7 January 2021

Nuclear antisense RNA induces extensive adenosine modifications and nuclear retention of target transcripts

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7 January 2021

Adenovirus VAI RNA antagonizes the RNA-editing activity of the ADAR adenosine deaminase

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7 January 2021

New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1

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7 January 2021

The molecular biology of hepatitis delta virus

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7 January 2021

Replication of human hepatitis delta virus: recent developments

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7 January 2021

The large form of hepatitis delta antigen is crucial for assembly of hepatitis delta virus

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7 January 2021

Effects of conserved RNA secondary structures on hepatitis delta virus genotype I RNA editing, replication, and virus production

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7 January 2021

Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1.

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7 January 2021

Inhibition of hepatitis delta virus RNA editing by short inhibitory RNA-mediated knockdown of ADAR1 but not ADAR2 expression.

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7 January 2021

Glutamate receptor ion channels

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7 January 2021

Regulation of ion channel/neurotransmitter receptor function by RNA editing

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7 January 2021

A-to-I editing: new and old sites, functions and speculations

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7 January 2021

Nervous system targets of RNA editing identified by comparative genomics

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7 January 2021

RNA editing activity is associated with splicing factors in lnRNP particles: The nuclear pre-mRNA processing machinery

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7 January 2021

Control of kinetic properties of AMPA receptor channels by nuclear RNA editing

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7 January 2021

Regulation of serotonin-2C receptor G-protein coupling by RNA editing

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Altered G protein-coupling functions of RNA editing isoform and splicing variant serotonin2C receptors

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency

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7 January 2021

Two naturally occurring alpha2,6-sialyltransferase forms with a single amino acid change in the catalytic domain differ in their catalytic activity and proteolytic processing

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7 January 2021

Two novel transcripts for human endothelin B receptor produced by RNA editing/alternative splicing from a single gene

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7 January 2021

Evolutionarily conserved human targets of adenosine to inosine RNA editing

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7 January 2021

Systematic identification of abundant A-to-I editing sites in the human transcriptome

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7 January 2021

Widespread RNA editing of embedded alu elements in the human transcriptome

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7 January 2021

Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome

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7 January 2021

Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly(A)+ RNA

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A bioinformatic screen for novel A-I RNA editing sites reveals recoding editing in BC10.

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7 January 2021

Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A mechanism for the control of protein synthesis by adenovirus VA RNAI.

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: RNA-binding activity of full-length and R-domain forms of the RNA-dependent protein kinase PKR--determination of KD values for VAI and TAR RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Role of the vaccinia virus E3L and K3L gene products in rescue of VSV and EMCV from the effects of IFN-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Complementation of vaccinia virus deleted of the E3L gene by mutants of E3L.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The human 2',5'-oligoadenylate synthetase family: interferon-induced proteins with unique enzymatic properties

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Vaccinia virus E3L protein is an inhibitor of the interferon (i.f.n.)-induced 2-5A synthetase enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Identification of a conserved motif that is necessary for binding of the vaccinia virus E3L gene products to double-stranded RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A ribonuclease specific for inosine-containing RNA: a potential role in antiviral defence?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The N-terminal domain of the vaccinia virus E3L-protein is required for neurovirulence, but not induction of a protective immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Antiviral actions of interferons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Increased RNA editing and inhibition of hepatitis delta virus replication by high-level expression of ADAR1 and ADAR2.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

By inhibiting replication, the large hepatitis delta antigen can indirectly regulate amber/W editing and its own expression

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interferon-alpha stimulation of liver cells enhances hepatitis delta virus RNA editing in early infection

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https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

AMPA receptor tetramerization is mediated by Q/R editing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Editing of glutamate receptor subunit B pre-mRNA by splice-site variants of interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Glutamate receptor RNA editing in vitro by enzymatic conversion of adenosine to inosine.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

5-HT2 receptor subtypes: a family re-united?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Messenger RNA editing of the human serotonin 5-HT2C receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Control of human potassium channel inactivation by editing of a small mRNA hairpin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanisms of gene silencing by double-stranded RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The role of RNA editing by ADARs in RNAi

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

High doses of siRNAs induce eri-1 and adar-1 gene expression and reduce the efficiency of RNA interference in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mutations in RNAi rescue aberrant chemotaxis of ADAR mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Chromosomal assignment of the interferon-inducible double-stranded RNA-dependent protein kinase (PRKR) to human chromosome 2p21-p22 and mouse chromosome 17 E2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Structural organization of the human gene (PKR) encoding an interferon-inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Sequence of the murine interferon-inducible RNA-dependent protein kinase (PKR) deduced from genomic clones

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Alternative splice variants of the human PKR protein kinase possessing different 5'-untranslated regions: expression in untreated and interferon-treated cells and translational activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: cDNA structure, expression, and regulation of the interferon-induced, RNA-dependent P1/eIF-2 alpha protein kinase from human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mouse interferon-inducible RNA-dependent protein kinase Pkr gene: cloning and sequence of the 5'-flanking region and functional identification of the minimal inducible promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The mRNA regulation of porcine double-stranded RNA-activated protein kinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The PKR kinase promoter binds both Sp1 and Sp3, but only Sp3 functions as part of the interferon-inducible complex with ISGF-3 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of the RNA-dependent protein kinase PKR promoter in the absence of interferon is dependent upon Sp proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: functional characterization of positive and negative regulatory domains that modulate transcriptional activation of the human RNA-dependent protein kinase Pkr promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

DNA damage-binding proteins and heterogeneous nuclear ribonucleoprotein A1 function as constitutive KCS element components of the interferon-inducible RNA-dependent protein kinase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Stat1 depends on transcriptional synergy with Sp1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

p48 Overexpression enhances interferon-mediated expression and activity of double-stranded RNA-dependent protein kinase in human hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Cloning and characterization of a cDNA encoding rat PKR, the double-stranded RNA-dependent eukaryotic initiation factor-2 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Phylogenetics and functions of the double-stranded RNA-binding motif: a genomic survey.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Dicing and slicing: the core machinery of the RNA interference pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The conformational plasticity of protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Molecular cloning and characterisation of a fish PKR-like gene from cultured CAB cells induced by UV-inactivated virus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Double-stranded RNA-specific adenosine deaminase: nucleic acid binding properties

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A poxvirus protein forms a complex with left-handed Z-DNA: crystal structure of a Yatapoxvirus Zalpha bound to DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Potential Alu function: regulation of the activity of double-stranded RNA-activated kinase PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Regulation of the interferon-induced PKR: can viruses cope?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Role of the RNA-dependent protein kinase in the regulated expression of genes in transfected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

PACT, a protein activator of the interferon-induced protein kinase, PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The double-stranded RNA-dependent protein kinase is also activated by heparin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Effects of length and location on the cellular response to double-stranded RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The double-stranded RNA-dependent protein kinase PKR: structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interactions between double-stranded RNA regulators and the protein kinase DAI

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The double-stranded-RNA-binding motif: interference and much more

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Serine 18 phosphorylation of RAX, the PKR activator, is required for PKR activation and consequent translation inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of the double-stranded-RNA-activated protein kinase and induction of vascular cell adhesion molecule-1 by poly (I).poly (C) in endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Translational control of viral gene expression in eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

eIF2 and the control of cell physiology

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The 58-kDa cellular inhibitor of the double stranded RNA-dependent protein kinase requires the tetratricopeptide repeat 6 and DnaJ motifs to stimulate protein synthesis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Expression of unphosphorylated form of human double-stranded RNA-activated protein kinase in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Double-stranded RNA-dependent protein kinase (PKR) is downregulated by phorbol ester

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The interferon response circuit: induction and suppression by pathogenic viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Complementation of deletion of the vaccinia virus E3L gene by the Escherichia coli RNase III gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Inhibition of PKR by vaccinia virus: role of the N- and C-terminal domains of E3L.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The Orf virus E3L homologue is able to complement deletion of the vaccinia virus E3L gene in vitro but not in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Homologous regions of the alpha subunit of eukaryotic translational initiation factor 2 (eIF2alpha) and the vaccinia virus K3L gene product interact with the same domain within the dsRNA-activated protein kinase (PKR)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

X-ray crystal structure and functional analysis of vaccinia virus K3L reveals molecular determinants for PKR subversion and substrate recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Regulation of the protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Seroepidemiology of herpes virus infections among dental personnel

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Dephosphorylation of eIF-2alpha mediated by the gamma(1)34.5 protein of herpes simplex virus type 1 is required for viral response to interferon but is not sufficient for efficient viral replication

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Dissecting the interferon-induced inhibition of hepatitis C virus replication by using a novel host cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interaction of the interferon-induced PKR protein kinase with inhibitory proteins P58IPK and vaccinia virus K3L is mediated by unique domains: implications for kinase regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Complete replication of hepatitis C virus in cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Isolation of novel virus-like sequences associated with human hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

GB virus type C NS5A sequence polymorphisms: association with interferon susceptibility and inhibition of PKR-mediated eIF2alpha phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The interferon-induced double-stranded RNA-activated human p68 protein kinase inhibits the replication of vaccinia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Vaccinia virus recombinants as a model system to analyze interferon-induced pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Lentivirus-mediated transduction of PKR into CD34(+) hematopoietic stem cells inhibits HIV-1 replication in differentiated T cell progeny

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RNA-dependent protein kinase is required for alpha-1 interferon transgene-induced resistance to genital herpes simplex virus type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

VSV replication in neurons is inhibited by type I IFN at multiple stages of infection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interferon-gamma-induced inhibition of neuronal vesicular stomatitis virus infection is STAT1 dependent.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interferon-gamma induced type I nitric oxide synthase activity inhibits viral replication in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interferon inhibits dengue virus infection by preventing translation of viral RNA through a PKR-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Lipopolysaccharide-induced impairment of classical swine fever virus infection in monocytic cells is sensitive to 2-aminopurine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

PKR's protective role in viral myocarditis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Newcastle disease virus V protein is associated with viral pathogenesis and functions as an alpha interferon antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Degradation of STAT1 and STAT2 by the V proteins of simian virus 5 and human parainfluenza virus type 2, respectively: consequences for virus replication in the presence of alpha/beta and gamma interferons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

NF-kappaB at the crossroads of life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

JNK2 and IKKbeta are required for activating the innate response to viral infection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of NF-kappa B by the dsRNA-dependent protein kinase, PKR involves the I kappa B kinase complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of the I kappa B alpha kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

TRAF family proteins link PKR with NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Encephalomyocarditis virus induces PKR-independent mitogen-activated protein kinase activation in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of NF-kappaB by double-stranded RNA (dsRNA) in the absence of protein kinase R and RNase L demonstrates the existence of two separate dsRNA-triggered antiviral programs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The dsRNA-dependent protein kinase, PKR and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The PKR protein kinase--an interferon-inducible regulator of cell growth and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Host defense, viruses and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Analysis of double-stranded RNA-induced apoptosis pathways using interferon-response noninducible small interfering RNA expression vector library

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Transcription stimulation of the Fas-encoding gene by nuclear factor for interleukin-6 expression upon influenza virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Inhibitory role of the host apoptogenic gene PKR in the establishment of persistent infection by encephalomyocarditis virus in U937 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The protein kinase PKR: a molecular clock that sequentially activates survival and death programs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Structure of the human APO-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Human Fas ligand: gene structure, chromosomal location and species specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Refined localization of dyschromatosis symmetrica hereditaria gene to a 9.4-cM region at 1q21-22 and a literature review of 136 cases reported in China

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mutations of the RNA-specific adenosine deaminase gene (DSRAD) are involved in dyschromatosis symmetrica hereditaria

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Identification of a locus for dyschromatosis symmetrica hereditaria at chromosome 1q11-1q21

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Identification of a novel mutation in the DSRAD gene in a Chinese pedigree with dyschromatosis symmetrica hereditaria

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Two frameshift mutations in the RNA-specific adenosine deaminase gene associated with dyschromatosis symmetrica hereditaria

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A new arginine substitution mutation of DSRAD gene in a Chinese family with dyschromatosis symmetrica hereditaria

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A novel mutation of the DSRAD gene in a Chinese family with dyschromatosis symmetrica hereditaria

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Novel mutations of the RNA-specific adenosine deaminase gene (DSRAD) in Chinese families with dyschromatosis symmetrica hereditaria

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mutation analysis of the ADAR1 gene in dyschromatosis symmetrica hereditaria and genetic differentiation from both dyschromatosis universalis hereditaria and acropigmentatio reticularis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Seven novel mutations of the ADAR gene in Chinese families and sporadic patients with dyschromatosis symmetrica hereditaria (DSH).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RNA editing of the 5-HT(2C) receptor is reduced in schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Editing for an AMPA receptor subunit RNA in prefrontal cortex and striatum in Alzheimer's disease, Huntington's disease and schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Expression of the double-stranded RNA-dependent protein kinase (p68) in human breast tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Expression of the double-stranded RNA-dependent protein kinase (p68) in squamous cell carcinoma of the head and neck region

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interferon-responsive protein kinase (p68) and proliferating cell nuclear antigen are inversely distributed in head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Expression of p68 in Human Colon Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Elevated apoptotic cell population in patients with chronic fatigue syndrome: the pivotal role of protein kinase RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Report of the committee on chromosome changes in neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Loss of PKR activity in chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Regulation of alternative splicing by RNA editing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Phylogenetic comparison of the pre-mRNA adenosine deaminase ADAR2 genes and transcripts: conservation and diversity in editing site sequence and alternative splicing patterns

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Novel splice variants of human ADAR2 mRNA: skipping of the exon encoding the dsRNA-binding domains, and multiple C-terminal splice sites

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Absence of PKR attenuates the anti-HSV-1 activity of an adenoviral vector expressing murine IFN-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

A specific base transition occurs on replicating hepatitis delta virus RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

Inhibition of replication of reactivated human immunodeficiency virus type 1 (HIV-1) in latently infected U1 cells transduced with an HIV-1 long terminal repeat-driven PKR cDNA construct

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2806%2981010-X

7 January 2021

10.1016/S0079-6603(06)81010-X

Identifiers

DOI

1 reference

14 August 2017

1 reference