(Q35145346)

6 August 2017

Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations (English)

1 reference

6 August 2017

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12

1 reference

6 August 2017

16

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Frédéric Rieux-Laucat

18

Frédéric Rieux-Laucat

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Marie-Claude Stolzenberg

6

Marie-Claude Stolzenberg

0 references

Patrick Nitschké

9

Patrick Nitschke

0 references

Matteo Gentili

Matteo Gentili

3

0 references

Nicolas Manel

Nicolas Manel

15

0 references

Thierry J Molina

Thierry J Molina

10

0 references

Gillian I. Rice

Gillian I Rice

13

0 references

Brigitte Bader-Meunier

Brigitte Bader-Meunier

17

0 references

Yanick J. Crow

Yanick J Crow

14

0 references

Bénédicte Neven

2

Bénédicte Neven

1 reference

6 August 2017

5

Sophia Maschalidi

1 reference

6 August 2017

1

Nadia Jeremiah

1 reference

6 August 2017

11

Stéphane Blanche

1 reference

6 August 2017

4

Isabelle Callebaut

1 reference

6 August 2017

Nicolas Goudin

7

1 reference

6 August 2017

Marie-Louis Frémond

8

1 reference

6 August 2017

Patrick Nitschke

9

1 reference

6 August 2017

language of work or name

English

0 references

publication date

17 November 2014

1 reference

Journal of Clinical Investigation

6 August 2017

1 reference

6 August 2017

124

1 reference

6 August 2017

5516-5520

1 reference

6 August 2017

12

1 reference

Activated STING in a vascular and pulmonary syndrome

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

STING recognition of cytoplasmic DNA instigates cellular defense

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Constitutive type I interferon modulates homeostatic balance through tonic signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348945

13 July 2018

Identifiers

DOI

10.1172/JCI79100

1 reference

6 August 2017

1 reference

6 August 2017

1 reference