(Q35145453)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Rachel G Scheraga

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Shaik O Rahaman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Lisa M Grove

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Sailaja Paruchuri

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Susamma Abraham

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Kathryn A Niese

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Sudakshina Ghosh

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Charles K Thodeti

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

David X Zhang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Magdalene M Moran

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

William P Schilling

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Daniel J Tschumperlin

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Mitchell A Olman

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

3 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

5225-5238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4348970/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts

13 July 2018

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Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis.

13 July 2018

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Extracellular matrix microenvironment contributes actively to pulmonary fibrosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Arachidonic acid-induced dilation in human coronary arterioles: convergence of signaling mechanisms on endothelial TRPV4-mediated Ca2+ entry

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

13 July 2018

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Tissue mechanics and fibrosis

13 July 2018

1 reference

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Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

13 July 2018

1 reference

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Resident mesenchymal cells and fibrosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo

13 July 2018

1 reference

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Targeting the TGFβ signalling pathway in disease

13 July 2018

1 reference

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Mechanisms of fibrosis: therapeutic translation for fibrotic disease

13 July 2018

1 reference

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Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness

13 July 2018

1 reference

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Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis

13 July 2018

1 reference

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A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis

13 July 2018

1 reference

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Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

13 July 2018

1 reference

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Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Mutations in TRPV4 cause an inherited arthropathy of hands and feet.

13 July 2018

1 reference

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Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function

13 July 2018

1 reference

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Delayed stress fiber formation mediates pulmonary myofibroblast differentiation in response to TGF-β.

13 July 2018

1 reference

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Transient receptor potential channels as therapeutic targets

13 July 2018

1 reference

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Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders

13 July 2018

1 reference

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TGF-β signaling in fibrosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

A multiwell platform for studying stiffness-dependent cell biology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

13 July 2018

1 reference

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Integrins and extracellular matrix in mechanotransduction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

13 July 2018

1 reference

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Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins

13 July 2018

1 reference

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Regulation of myofibroblast activities: calcium pulls some strings behind the scene

13 July 2018

1 reference

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TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Identification and characterization of novel TRPV4 modulators

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Molecular mechanisms of TRPV4-mediated neural signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Bone marrow-derived progenitor cells in pulmonary fibrosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Disorders of lung matrix remodeling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Calcium signalling: dynamics, homeostasis and remodelling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Impaired osmotic sensation in mice lacking TRPV4

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Myocardial fibrosis associated with aldosterone or angiotensin II administration: attenuation by calcium channel blockade.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Transforming growth factor-β evokes Ca2+ waves and enhances gene expression in human pulmonary fibroblasts.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

An essential role for fibronectin extra type III domain A in pulmonary fibrosis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Transforming growth factor beta stimulates fibroblast-collagen matrix contraction by different mechanisms in mechanically loaded and unloaded matrices.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Pa

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4348970

Idiopathic pulmonary fibrosis

16 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25365224

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI75331

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25365224%20AND%20SRC:MED&resulttype=core&format=json