(Q35147454)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author

María Fernanda Pascutti

1

1 reference

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2 March 2020

Klaas Pjm van Gisbergen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Rene van Lier

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Monika C Wolkers

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Martijn A. Nolte

9

1 reference

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2 March 2020

2

Sulima Geerman

1 reference

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2 March 2020

3

Edith Slot

1 reference

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2 March 2020

5

Louis Boon

1 reference

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2 March 2020

6

Ramon Arens

1 reference

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2 March 2020

publication date

4 March 2015

1 reference

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2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

11

1 reference

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2 March 2020

issue

3

1 reference

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2 March 2020

page(s)

e1004675

1 reference

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Creative Commons Attribution 4.0 International

2 March 2020

copyright license

start time

4 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Anti-GITR agonist therapy intrinsically enhances CD8 T cell responses to chronic lymphocytic choriomeningitis virus (LCMV), thereby circumventing LCMV-induced downregulation of costimulatory GITR ligand on APC.

1 reference

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Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection

13 July 2018

1 reference

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Molecular and transcriptional basis of CD4⁺ T cell dysfunction during chronic infection

13 July 2018

1 reference

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Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugs

13 July 2018

1 reference

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Cell-specific and context-dependent effects of GITR in cancer, autoimmunity, and infection

13 July 2018

1 reference

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Effector-like CD8⁺ T cells in the memory population mediate potent protective immunity

13 July 2018

1 reference

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Modulation of Treg cells/T effector function by GITR signaling is context-dependent

13 July 2018

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The depletion of NK cells prevents T cell exhaustion to efficiently control disseminating virus infection

13 July 2018

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OX40 facilitates control of a persistent virus infection

13 July 2018

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Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

13 July 2018

1 reference

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Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

13 July 2018

1 reference

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Pharmacological modulation of GITRL/GITR system: therapeutic perspectives.

13 July 2018

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13 July 2018

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Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.

13 July 2018

1 reference

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Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

13 July 2018

1 reference

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Autoimmunity associated with immunotherapy of cancer

13 July 2018

1 reference

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Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens

13 July 2018

1 reference

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Translating insights from persistent LCMV infection into anti-HIV immunity

13 July 2018

1 reference

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PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

13 July 2018

1 reference

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Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion

13 July 2018

1 reference

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GITR: a modulator of immune response and inflammation.

13 July 2018

1 reference

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

13 July 2018

1 reference

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High antigen levels are the cause of T cell exhaustion during chronic viral infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology

13 July 2018

1 reference

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The role of TNF superfamily members in T-cell function and diseases

13 July 2018

1 reference

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Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

13 July 2018

1 reference

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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

13 July 2018

1 reference

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Elimination of chronic viral infection by blocking CD27 signaling.

13 July 2018

1 reference

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

13 July 2018

1 reference

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Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity

13 July 2018

1 reference

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Antiviral antibody responses: the two extremes of a wide spectrum

13 July 2018

1 reference

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In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

TNF/TNFR family members in costimulation of T cell responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Cloning and characterization of GITR ligand

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Viral immune evasion due to persistence of activated T cells without effector function

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Phenotypic analysis of antigen-specific T lymphocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Cells that express viral antigens but lack H-2 determinants are not lysed by immune thymus-derived lymphocytes but are lysed by other antiviral immune attack mechanisms

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

CD8+ T cells: GITR matters.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

The price of the CD27-CD70 costimulatory axis: you can't have it all.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349659

Conversion of alloantigen-specific CD8+ T cell anergy to CD8+ T cell priming through in vivo ligation of glucocorticoid-induced TNF receptor

27 September 2018

1 reference

12 December 2020

Glucocorticoid-induced TNFR-related protein lowers the threshold of CD28 costimulation in CD8+ T cells

1 reference

12 December 2020

CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection

1 reference

12 December 2020

Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1004675

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25738498%20AND%20SRC:MED&resulttype=core&format=json