(Q35153276)

English

An imbalance in antioxidant defense affects cellular function: the pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

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scholarly article

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

An imbalance in antioxidant defense affects cellular function: the pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse (English)

1 reference

Europe PubMed Central

6 August 2017

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pathophysiology

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based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

Paul J Hertzog

5

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ORCID Public Data File 2021

author name string

Judy B De Haan

1

1 reference

Europe PubMed Central

6 August 2017

Peter J Crack

2

1 reference

Europe PubMed Central

6 August 2017

Nicole Flentjar

3

1 reference

Europe PubMed Central

6 August 2017

Rocco C Iannello

4

1 reference

Europe PubMed Central

6 August 2017

Ismail Kola

6

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Europe PubMed Central

6 August 2017

publication date

1 January 2003

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Europe PubMed Central

6 August 2017

number of pages

11

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Europe PubMed Central

6 August 2017

8

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Europe PubMed Central

6 August 2017

2

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Europe PubMed Central

6 August 2017

69-79

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Europe PubMed Central

6 August 2017

Aging: a theory based on free radical and radiation chemistry

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Strategies of antioxidant defense

1 reference

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21 January 2018

Oxidative stress: from basic research to clinical application

1 reference

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21 January 2018

Oxidative stress as a causal factor in differentiation and aging: a unifying hypothesis

1 reference

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21 January 2018

Monitoring of oxidative free radical damage in vivo: analytical aspects

1 reference

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21 January 2018

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1 reference

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21 January 2018

Regulation of the macrophage oxidative burst by mediators: effects of inhibitors.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Free radical involvement in aging. Pathophysiology and therapeutic implications

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Elevation in the ratio of Cu/Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Oxidants, antioxidants, and the degenerative diseases of aging

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

1 reference

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21 January 2018

Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

1 reference

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21 January 2018

The balance between copper-zinc superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress

1 reference

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21 January 2018

Cold-induced brain edema and infarction are reduced in transgenic mice overexpressing CuZn-Superoxide dismutase

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Overexpression of Cu2+/Zn2+ superoxide dismutase protects against early diabetic glomerular injury in transgenic mice

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Ischemic reperfusion brain injury in fetal transgenic mice with elevated levels of copper-zinc superoxide dismutase

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Oxidative stress mediates impairment of muscle function in transgenic mice with elevated level of wild-type Cu/Zn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Ultrastructural studies of young and old mouse neuromuscular junctions.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Age-related changes in antioxidant enzymes and lipid peroxidation in brains of control and transgenic mice overexpressing copper-zinc superoxide dismutase.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Tissue-specific functions of individual glutathione peroxidases

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Paraquat-resistant HeLa cells: increased cellular content of glutathione peroxidase.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

The role of selenium peroxidases in the protection against oxidative damage of membranes

1 reference

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21 January 2018

Constitutive overexpression of Cu/Zn superoxide dismutase exacerbates kainic acid-induced apoptosis of transgenic-Cu/Zn superoxide dismutase neurons

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Signalling apoptosis: a radical approach.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Lipopolysaccharide and interferon-gamma-induced nitric oxide production and protein oxidation in mouse peritoneal macrophages are affected by glutathione peroxidase-1 gene knockout.

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Variation in cellular glutathione peroxidase activity in lens epithelial cells, transgenics and knockouts does not significantly change the response to H2O2 stress

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

The effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stress

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Ebselen, a selenoorganic compound as glutathione peroxidase mimic

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Physiological and nutritional importance of selenium

1 reference

https://api.crossref.org/works/10.1179%2F135100003125001378

21 January 2018

Free Radicals in Biological Materials

1 reference

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21 January 2018

Reactive Oxygen Species and Their Contribution to Pathology in Down Syndrome

1 reference

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21 January 2018

Identifiers

10.1179/135100003125001378

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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