(Q35157680)

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Molecular and cellular mechanisms of action of the vacuolating cytotoxin (VacA) and neutrophil-activating protein (HP-NAP) virulence factors of Helicobacter pylori

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Europe PubMed Central

PubMed publication ID

6 August 2017

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Europe PubMed Central

Molecular and cellular mechanisms of action of the vacuolating cytotoxin (VacA) and neutrophil-activating protein (HP-NAP) virulence factors of Helicobacter pylori (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Helicobacter pylori

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Helicobacter pylori infectious disease

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inferred from title

Cesare Montecucco

1

object named as

Cesare Montecucco

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Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Marina de Bernard

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

publication date

1 July 2003

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Europe PubMed Central

PubMed publication ID

6 August 2017

Microbes and Infection

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Europe PubMed Central

PubMed publication ID

6 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

715-721

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Helicobacter pylori: microbiology of a 'slow' bacterial infection

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Tyrosine-phosphorylated bacterial proteins: Trojan horses for the host cell

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Cytotoxic activity in broth-culture filtrates of Campylobacter pylori

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Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein

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Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease

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Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin

1 reference

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3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin

1 reference

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Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant

1 reference

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Acid-induced dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals its pattern of assembly

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Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase beta.

1 reference

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The acid activation of Helicobacter pylori toxin VacA: structural and membrane binding studies

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Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol

1 reference

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Identification of the minimal intracellular vacuolating domain of the Helicobacter pylori vacuolating toxin

1 reference

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Mutational analysis of the Helicobacter pylori vacuolating toxin amino terminus: identification of amino acids essential for cellular vacuolation

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A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation

1 reference

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Expression and binding analysis of GST-VacA fusions reveals that the C-terminal approximately 100-residue segment of exotoxin is crucial for binding in HeLa cells

1 reference

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Morphologic differentiation of HL-60 cells is associated with appearance of RPTPbeta and induction of Helicobacter pylori VacA sensitivity

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Vacuolation induced by cytotoxin from Helicobacter pylori is mediated by the EGF receptor in HeLa cells

1 reference

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Helicobacter pylori vacuolating cytotoxin binds to the 140-kDa protein in human gastric cancer cell lines, AZ-521 and AGS.

1 reference

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High cell sensitivity to Helicobacter pylori VacA toxin depends on a GPI-anchored protein and is not blocked by inhibition of the clathrin-mediated pathway of endocytosis

1 reference

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Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts

1 reference

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7 January 2021

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Plasma membrane cholesterol modulates cellular vacuolation induced by the Helicobacter pylori vacuolating cytotoxin

1 reference

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Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers

1 reference

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The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin.

1 reference

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Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase

1 reference

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Characterization of HeLa cell vacuoles induced by Helicobacter pylori broth culture supernatant

1 reference

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Cell vacuolization induced by Helicobacter pylori VacA cytotoxin does not depend on late endosomal SNAREs+

1 reference

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Dynamin is involved in human epithelial cell vacuolation caused by the Helicobacter pylori-produced cytotoxin VacA

1 reference

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Effect of helicobacter pylori vacuolating toxin on maturation and extracellular release of procathepsin D and on epidermal growth factor degradation

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Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA.

1 reference

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Persistent infection by Helicobacter pylori down-modulates virus-specific CD8+ cytotoxic T cell response and prolongs viral infection

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Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin

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Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells

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Helicobacter pylori strains expressing the vacuolating cytotoxin interrupt phagosome maturation in macrophages by recruiting and retaining TACO (coronin 1) protein

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Helicobacter pylori vacuolating toxin forms anion-selective channels in planar lipid bilayers: possible implications for the mechanism of cellular vacuolation.

1 reference

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Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity.

1 reference

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Living dangerously: how Helicobacter pylori survives in the human stomach

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Inhibition of the vacuolating and anion channel activities of the VacA toxin of Helicobacter pylori

1 reference

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Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin

1 reference

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Vacuolation induced by VacA toxin of Helicobacter pylori requires the intracellular accumulation of membrane permeant bases, Cl(-) and water

1 reference

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Enterotoxic Effect of the Vacuolating Toxin Produced byHelicobacter pyloriin Caco‐2 Cells

1 reference

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Helicobacter pylori cytotoxin VacA increases alkaline secretion in gastric epithelial cells

1 reference

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7 January 2021

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The Helicobacter pylori VacA toxin is a urea permease that promotes urea diffusion across epithelia

1 reference

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Characterization of a Helicobacter pylori neutrophil-activating protein.

1 reference

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7 January 2021

based on heuristic

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The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a protective antigen and a major virulence factor

1 reference

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Neutrophil-activating protein mediates adhesion of Helicobacter pylori to sulfated carbohydrates on high-molecular-weight salivary mucin

1 reference

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Carbohydrate binding specificity of the neutrophil-activating protein of Helicobacter pylori

1 reference

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The neutrophil-activating protein of Helicobacter pylori (HP-NAP) activates the MAPK pathway in human neutrophils

1 reference

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Helicobacter pylori neutrophil-activating protein stimulates tissue factor and plasminogen activator inhibitor-2 production by human blood mononuclear cells

1 reference

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The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a potent stimulant of mast cells

1 reference

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7 January 2021

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Structure of the neutrophil-activating protein from Helicobacter pylori

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Identification of four new prokaryotic bacterioferritins, from Helicobacter pylori, Anabaena variabilis, Bacillus subtilis and Treponema pallidum, by analysis of gene sequences.

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The neutrophil-activating protein of Helicobacter pylori

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Identifiers

10.1016/S1286-4579(03)00124-2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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