(Q35157847)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Weixi Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jeffry S Nyman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Heather E Moss

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Gloria Gutierrez

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Gregory R Mundy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Xiangli Yang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

1 July 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

Journal of Bone and Mineral Research

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

1658-1667

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin

19 January 2020

cites work

1 reference

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Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling.

13 July 2018

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Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone

13 July 2018

1 reference

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Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair.

13 July 2018

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The immature spine in type-1 neurofibromatosis

13 July 2018

1 reference

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ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae

13 July 2018

1 reference

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Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions

13 July 2018

1 reference

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Lovastatin inhibits the extracellular-signal-regulated kinase pathway in immortalized rat brain neuroblasts

13 July 2018

1 reference

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Double inactivation of NF1 in tibial pseudarthrosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Statins and bone metabolism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

A single systemic dose of pamidronate improves bone mineral content and accelerates restoration of strength in a rat model of fracture repair

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Hydroxymethylglutaryl-coenzyme A reductase inhibitors and osteoporosis: a meta-analysis.

13 July 2018

1 reference

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Neurofibromatosis 1: closing the GAP between mice and men.

13 July 2018

1 reference

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Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

NF1 tumor suppressor gene function: narrowing the GAP

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Congenital pseudarthrosis of the tibia: a retrospective review

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Neurofibromatosis in children: the role of the orthopaedist.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Osseous manifestations of neurofibromatosis in childhood

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Associations of osseous abnormalities in Neurofibromatosis 1.

13 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FJBMR.42

Skeletal abnormalities in neurofibromatosis type 1: approaches to therapeutic options.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FJBMR.42

High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Own clinical experience with functional bracing for treatment of pseudarthrosis and delayed union of the tibia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Multiple roles for neurofibromin in skeletal development and growth

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Distribution of lovastatin to bone and its effect on bone turnover in rats.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Novel compound enables high-level adenovirus transduction in the absence of an adenovirus-specific receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Depressed bone mineralization following high dose TGF-beta1 application in an orthopedic implant model

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Mitigation of ectopic calcification in osteopontin-deficient mice by exogenous osteopontin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.

27 September 2018

1 reference

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Effects of simvastatin on bone turnover and BMD: a 1-year randomized controlled trial in postmenopausal osteopenic women

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Simvastatin treatment partially prevents ovariectomy-induced bone loss while increasing cortical bone formation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Simvastatin improves fracture healing in mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Orthopaedic manifestations of neurofibromatosis in children: an update.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Relation of statin use and bone loss: a prospective population-based cohort study in early postmenopausal women

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Effect of HMG-CoA reductase inhibitors (statins) on bone mineral density

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Descriptive analysis of tibial pseudarthrosis in patients with neurofibromatosis 1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Type 1 neurofibromatosis: a descriptive analysis of the disorder in 1,728 patients.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154004

Pathology of bone lesions associated with congenital pseudarthrosis of the leg

27 September 2018

1 reference

12 December 2020

Locally delivered lovastatin nanoparticles enhance fracture healing in rats

1 reference

12 December 2020

Models of tibial fracture healing in normal and Nf1-deficient mice

1 reference

12 December 2020

A radiographic and histologic study of fracture healing in osteopetrotic rats

1 reference

12 December 2020

Production of a standard closed fracture in laboratory animal bone

1 reference

12 December 2020

Congenital pseudarthrosis of the tibia: treatment by transfer of the ipsilateral fibula with vascular pedicle

1 reference

12 December 2020

Neurofibromin and its inactivation of Ras are prerequisites for osteoblast functioning

1 reference

12 December 2020

Congenital pseudarthrosis of the tibia: Part 1. European Pediatric Orthopaedic Society multicenter study of congenital pseudoarthrosis

1 reference

12 December 2020

Transdermal application of lovastatin to rats causes profound increases in bone formation and plasma concentrations

1 reference

12 December 2020

Identifiers

DOI

10.1002/JBMR.42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20200958%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

20200958

1 reference