(Q36838089)

16 August 2017

Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin (English)

1 reference

16 August 2017

3

Nadine Kossler

0 references

Jirko Kühnisch

2

object named as

Jirko Kühnisch

0 references

Boris Thurisch

6

object named as

Boris Thurisch

0 references

Stefan Mundlos

8

object named as

Stefan Mundlos

1 reference

16 August 2017

Mateusz Kolanczyk

1

1 reference

16 August 2017

Monika Osswald

4

1 reference

16 August 2017

Sabine Stumpp

5

1 reference

16 August 2017

Uwe Kornak

7

1 reference

16 August 2017

language of work or name

English

0 references

publication date

31 July 2008

1 reference

16 August 2017

1 reference

16 August 2017

6

1 reference

16 August 2017

21

1 reference

https://scigraph.springernature.com/pub.10.1186/1741-7015-6-21

16 August 2017

0 references

cites work

Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Locally applied Simvastatin improves fracture healing in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Double inactivation of NF1 in tibial pseudarthrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Statins and osteoporosis: new role for old drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

The role of protease-activated receptor-1 in bone healing.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Decreased bone mineral density and content in neurofibromatosis type 1: lowest local values are located in the load-carrying parts of the body

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Directions of drug discovery in osteoporosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Hypophosphatemic osteomalacia in von Recklinghausen neurofibromatosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Protein prenylation: key to ras function and cancer intervention?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Descriptive analysis of tibial pseudarthrosis in patients with neurofibromatosis 1.

27 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-6-21

Multiple roles for neurofibromin in skeletal development and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-6-21

Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-6-21

Simvastatin improves fracture healing in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-6-21

Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-6-21

Erk pathways negatively regulate matrix mineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-6-21

Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516519

Vascular changes in the periosteum of congenital pseudarthrosis of the tibia

5 September 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-6-21

Neurofibromin and its inactivation of Ras are prerequisites for osteoblast functioning

21 January 2018

1 reference

12 December 2020

Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone

1 reference

12 December 2020

Establishment of a Model of Cortical Bone Repair in Mice

1 reference

12 December 2020

Hypercalcemic hyperparathyroidism and hypophosphatemic osteomalacia complicating neurofibromatosis

1 reference

12 December 2020

Oncogenic osteomalacia induced by schwannoma in a patient with neurofibromatosis

1 reference

12 December 2020

Vasculopathy in two cases of NF1-related congenital pseudarthrosis

1 reference

12 December 2020

Congenital pseudarthrosis of the tibia: analysis of the histology and the NF1 gene

1 reference

12 December 2020

Locally delivered lovastatin nanoparticles enhance fracture healing in rats

1 reference

12 December 2020

Identifiers

DOI

10.1186/1741-7015-6-21

1 reference

Dimensions Publication ID

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

18671844

1 reference