(Q35157993)

6 August 2017

1 reference

title

Pharmacogenomics of human UDP-glucuronosyltransferase enzymes (English)

1 reference

6 August 2017

1 reference

Guillemette C

1

1 reference

6 August 2017

1 January 2003

1 reference

The Pharmacogenomics Journal

6 August 2017

1 reference

6 August 2017

3

1 reference

6 August 2017

136-158

1 reference

6 August 2017

3

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.tpj.6500171

6 August 2017

0 references

cites work

Pharmacogenomics: translating functional genomics into rational therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Characterization and regulation of UDP-glucuronosyltransferases in steroid target tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Characterization of UDP-glucuronosyltransferases active on steroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Pharmacogenetics in clinical pharmacology and toxicology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

The genetic origin of responses to drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

The role of individual human cytochromes P450 in drug metabolism and clinical response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Disposition of lorazepam in Gilbert's syndrome: effects of fasting, feeding, and enterohepatic circulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Paracetamol (acetaminophen) kinetics in patients with Gilber's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Alteration of drug metabolism in Gilbert's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Interethnic variation of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Drug glucuronidation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Interindividual variability in the glucuronidation and sulphation of ethinyloestradiol in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Variability of diphenhydramine N-glucuronidation in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Gilbert??s Syndrome and Drug Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Metabolism of epirubicin to glucuronides: relationship to the pharmacodynamics of the drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Interindividual and interethnic differences in the demethylation and glucuronidation of codeine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Indices and graphical approaches for the detection of interindividual and interethnic variations in codeine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

UDP-glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

UDP-Glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Isolation and characterization of the human UGT2B15 gene, localized within a cluster of UGT2B genes and pseudogenes on chromosome 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

cDNA cloning and characterization of the human UDP glucuronosyltransferase, UGT1A3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Isolation and characterization of the human UGT2B7 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genomic organization of the UGT2b gene cluster on human chromosome 4q13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Odorant signal termination by olfactory UDP glucuronosyl transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Structural and functional studies of UDP-glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Hepatic Bilirubin UDP-Glucuronyl Transferase Activity in Liver Disease and Gilbert's Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Molecular genetic basis of Gilbert's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic interactions in the pathogenesis of neonatal hyperbilirubinemia: Gilbert's Syndrome and glucose-6-phosphate dehydrogenase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Interaction of coding region mutations and the Gilbert-type promoter abnormality of the UGT1A1 gene causes moderate degrees of unconjugated hyperbilirubinaemia and may lead to neonatal kernicterus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Polymorphisms in steroid hormone pathway genes and mammographic density

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Glucuronidation of thyroid hormone by human bilirubin and phenol UDP-glucuronyltransferase isoenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Identification of a rat oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with activity towards benzo(a)pyrene-7,8-dihydrodiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Interpretation of genetic association studies in complex disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Human UDP-glucuronosyltransferase 2B7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 and UGT1A8*3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Two human liver cDNAs encode UDP-glucuronosyltransferases with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Structure of the human UGT2B4 gene encoding a bile acid UDP-glucuronosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Identification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Sequence of exons and the flanking regions of human bilirubin-UDP-glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler-Najjar syndrome, type I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Identification of an A-to-G missense mutation in exon 2 of the UGT1 gene complex that causes Crigler-Najjar syndrome type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Identification of two single base substitutions in the UGT1 gene locus which abolish bilirubin uridine diphosphate glucuronosyltransferase activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic heterogeneity of Crigler-Najjar syndrome type I: a study of 14 cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

A new type of defect in the gene for bilirubin uridine 5'-diphosphate-glucuronosyltransferase in a patient with Crigler-Najjar syndrome type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Gilbert's syndrome is caused by a heterozygous missense mutation in the gene for bilirubin UDP-glucuronosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

A mutation which disrupts the hydrophobic core of the signal peptide of bilirubin UDP-glucuronosyltransferase, an endoplasmic reticulum membrane protein, causes Crigler-Najjar type II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Coding defect and a TATA box mutation at the bilirubin UDP-glucuronosyltransferase gene cause Crigler-Najjar type I disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Kernicterus in an adult who is heterozygous for Crigler-Najjar syndrome and homozygous for Gilbert-type genetic defect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Splice-site mutations: a novel genetic mechanism of Crigler-Najjar syndrome type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Low glucose-6-phosphate dehydrogenase enzyme activity level at the time of hemolysis in a male neonate with the African type of deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Influence of bilirubin uridine diphosphate-glucuronosyltransferase 1A promoter polymorphisms on serum bilirubin levels and cholelithiasis in children with sickle cell anemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: a dose-dependent genetic interaction crucial to neonatal hyperbilirubinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Gilbert syndrome accelerates development of neonatal jaundice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

Glucuronidation of carcinogenic arylamines and their N-hydroxy derivatives by rat and human phenol UDP-glucuronosyltransferase of the UGT1 gene complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Species differences of glucuronidation and sulfation in relation to hepatocarcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Glucuronidation of SN-38, the Active Metabolite of Irinotecan, by Human Hepatic Microsomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Severe CPT-11 toxicity in patients with Gilbert's syndrome: two case reports

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Urinary excretion of valproate and some metabolites in chronically treated patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Paracetamol as a test drug to determine glucuronide formation in man. Effects of inducers and of smoking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Normal pathways for glucuronidation, sulphation and oxidation of paracetamol in Gilbert's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Urinary glucuronide excretion of fenofibric and clofibric acid glucuronides in man. Is it polymorphic?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Interindividual variation in the levels of certain urinary polycyclic aromatic hydrocarbon metabolites following medicinal exposure to coal tar ointment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

An allele-specific polymerase chain reaction method for the determination of the D85Y polymorphism in the human UDP-glucuronosyltransferase 2B15 gene in a case-control study of prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl beta-glucuronide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Gene structure at the human UGT1 locus creates diversity in isozyme structure, substrate specificity, and regulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Genetic multiplicity of the human UDP-glucuronosyltransferases and regulation in the gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Bilirubin glucuronide formation in vitro; demonstration of a defect in Gilbert's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Gilbert's syndrome is a contributory factor in prolonged unconjugated hyperbilirubinemia of the newborn

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Association of neonatal hyperbilirubinemia with bilirubin UDP-glucuronosyltransferase polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Neonatal hyperbilirubinemia and a common mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene in Japanese

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

UDP-glucuronosyltransferases in human intestinal mucosa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

The regio- and stereo-selectivity of C19 and C21 hydroxysteroid glucuronidation by UGT2B7 and UGT2B11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

A mutation in bilirubin uridine 5'-diphosphate-glucuronosyltransferase isoform 1 causing Crigler-Najjar syndrome type II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Genetic defects at the UGT1 locus associated with Crigler-Najjar type I disease, including a prenatal diagnosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Crigler-Najjar syndrome type II is inherited both as a dominant and as a recessive trait

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

A novel compound heterozygous variation of the uridine-diphosphoglucuronosyl transferase 1A1 gene that causes Crigler-Najjar syndrome type II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

A novel intronic mutation results in the use of a cryptic splice acceptor site within the coding region of UGT1A1, causing Crigler-Najjar syndrome type 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Analysis of bilirubin uridine 5'-diphosphate (UDP)-glucuronosyltransferase gene mutations in seven patients with Crigler-Najjar syndrome type II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

The expression of uridine diphosphate glucuronosyltransferase gene is a major determinant of bilirubin level in heterozygous beta-thalassaemia and in glucose-6-phosphate dehydrogenase deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

UGT1*1 genotyping in a Canadian Inuit population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500171

7 January 2021

Identifiers

DOI

10.1038/SJ.TPJ.6500171

1 reference

6 August 2017

1 reference

PubMed ID

12815363