(Q35159821)

6 August 2017

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title

Sulphonylurea action revisited: the post-cloning era. (English)

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6 August 2017

Gribble FM

1

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6 August 2017

Reimann F

series ordinal

2

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6 August 2017

publication date

18 June 2003

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6 August 2017

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6 August 2017

volume

46

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6 August 2017

issue

7

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6 August 2017

page(s)

875-891

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https://scigraph.springernature.com/pub.10.1007/s00125-003-1143-3

6 August 2017

exact match

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cites work

K(ATP) channels and insulin secretion disorders

1 reference

12 December 2020

Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy

1 reference

12 December 2020

Long-term comparative trial of glibenclamide and chlorpropamide in diet-failed, maturity-onset diabetics

1 reference

12 December 2020

Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle

1 reference

12 December 2020

Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure

1 reference

12 December 2020

The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide

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12 December 2020

Phosphoinositides decrease ATP sensitivity of the cardiac ATP-sensitive K(+) channel. A molecular probe for the mechanism of ATP-sensitive inhibition

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12 December 2020

Association and stoichiometry of K(ATP) channel subunits

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12 December 2020

ATP-sensitive potassium channels, transmural ischemia and the ECG implications for the non-insulin dependent diabetic patient?

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12 December 2020

Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure

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12 December 2020

Transmembrane topology of the sulfonylurea receptor SUR1.

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12 December 2020

Cardioprotection by opening of the K(ATP) channel in unstable angina. Is this a clinical manifestation of myocardial preconditioning? Results of a randomized study with nicorandil. CESAR 2 investigation. Clinical European studies in angina and revas

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12 December 2020

A K(ATP) channel deficiency affects resting tension, not contractile force, during fatigue in skeletal muscle

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12 December 2020

Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons

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12 December 2020

Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channels

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12 December 2020

The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells

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12 December 2020

E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.

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12 December 2020

Adenosine triphosphate-sensitive potassium channels in the cardiovascular system

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12 December 2020

Kir6.1 is the principal pore-forming subunit of astrocyte but not neuronal plasma membrane K-ATP channels

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12 December 2020

Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.

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12 December 2020

Physiological and pathophysiological roles of ATP-sensitive K+ channels

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12 December 2020

The molecular basis of the specificity of action of K(ATP) channel openers

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12 December 2020

MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit.

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12 December 2020

cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells

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12 December 2020

Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K+ conductance

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12 December 2020

Sulfonylureas, ATP-sensitive K+ channels, and cellular K+ loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle

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12 December 2020

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

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12 December 2020

Ischemic preconditioning during coronary angioplasty is prevented by glibenclamide, a selective ATP-sensitive K+ channel blocker.

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12 December 2020

Glucose-sensing in glucagon-like peptide-1-secreting cells

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12 December 2020

Pharmaco-topology of sulfonylurea receptors. Separate domains of the regulatory subunits of K(ATP) channel isoforms are required for selective interaction with K(+) channel openers

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12 December 2020

Creatine kinase is physically associated with the cardiac ATP-sensitive K+ channel in vivo

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12 December 2020

ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue

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12 December 2020

Investigation of the molecular assembly of beta-cell K(ATP) channels

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12 December 2020

Adenosine diphosphate as an intracellular regulator of insulin secretion.

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12 December 2020

Gliclazide produces high-affinity block of KATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells

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12 December 2020

Disruption of Sur2-containing K(ATP) channels enhances insulin-stimulated glucose uptake in skeletal muscle

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12 December 2020

Identification of the potassium channel opener site on sulfonylurea receptors

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12 December 2020

The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint

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12 December 2020

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

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12 December 2020

A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels

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12 December 2020

Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides

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12 December 2020

K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels

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12 December 2020

SUR-dependent modulation of KATP channels by an N-terminal KIR6.2 peptide. Defining intersubunit gating interactions

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12 December 2020

Symptomatic hypoglycemia in NIDDM patients treated with oral hypoglycemic agents

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12 December 2020

Molecular basis of electrocardiographic ST-segment elevation

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12 December 2020

MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1.

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12 December 2020

ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

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12 December 2020

A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel

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12 December 2020

ATP-Sensitive potassium channels: a review of their cardioprotective pharmacology

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12 December 2020

Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice

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12 December 2020

Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide.

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12 December 2020

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

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12 December 2020

A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1.

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12 December 2020

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

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12 December 2020

ATP-sensitive K+ channels and insulin secretion: their role in health and disease.

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12 December 2020

Cytosolic ADP enhances the sensitivity to tolbutamide of ATP-dependent K+ channels from pancreatic B-cells

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12 December 2020

Effects of the I(K.ATP) blockers glibenclamide and HMR1883 on cardiac electrophysiology during ischemia and reperfusion

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12 December 2020

Cation transport in mitochondria--the potassium cycle

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12 December 2020

Characterization of two novel forms of the rat sulphonylurea receptor SUR1A2 and SUR1BDelta31

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12 December 2020

Glibenclamide attenuates peaked T wave in early phase of myocardial ischemia.

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12 December 2020

Glibenclamide binding to sulphonylurea receptor subtypes: dependence on adenine nucleotides

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12 December 2020

Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels

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12 December 2020

ATP binding properties of the nucleotide-binding folds of SUR1.

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12 December 2020

Cytosolic nucleotides enhance the tolbutamide sensitivity of the ATP-dependent K+ channel in mouse pancreatic B cells by their combined actions at inhibitory and stimulatory receptors

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12 December 2020

A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line

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12 December 2020

Interaction of K(ATP) channel modulators with sulfonylurea receptor SUR2B: implication for tetramer formation and allosteric coupling of subunits

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12 December 2020

Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1

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12 December 2020

Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy

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12 December 2020

M-LDH serves as a sarcolemmal K(ATP) channel subunit essential for cell protection against ischemia

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12 December 2020

ATP-regulated K+ channels in cardiac muscle

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12 December 2020

The catalytic cycle of P-glycoprotein

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12 December 2020

Roles of ATP-sensitive K+ channels in cell survival and differentiation in the endocrine pancreas

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12 December 2020

Octameric stoichiometry of the KATP channel complex

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12 December 2020

Differential interactions of nateglinide and repaglinide on the human beta-cell sulphonylurea receptor 1.

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12 December 2020

Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population

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12 December 2020

Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channel

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12 December 2020

Electrogenic arginine transport mediates stimulus-secretion coupling in mouse pancreatic beta-cells

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12 December 2020

A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells

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12 December 2020

The beta-cell glibenclamide receptor is an ADP-binding protein

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12 December 2020

Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

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12 December 2020

Cytoplasmic terminus domains of Kir6.x confer different nucleotide-dependent gating on the ATP-sensitive K+ channel

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12 December 2020

ATPase activity of the sulfonylurea receptor: a catalytic function for the KATP channel complex.

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12 December 2020

Characterization of low-affinity binding sites for glibenclamide on the Kir6.2 subunit of the beta-cell KATP channel

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12 December 2020

Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels

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12 December 2020

Structural basis for the interference between nicorandil and sulfonylurea action

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12 December 2020

Variations in insulin secretion in carriers of the E23K variant in the KIR6.2 subunit of the ATP-sensitive K(+) channel in the beta-cell

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12 December 2020

Identification and characterization of glucoresponsive neurons in the enteric nervous system.

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12 December 2020

C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K(+) channels

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12 December 2020

The insulin secretory granule is the major site of K(ATP) channels of the endocrine pancreas

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12 December 2020

Coexpression with the inward rectifier K(+) channel Kir6.1 increases the affinity of the vascular sulfonylurea receptor SUR2B for glibenclamide

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12 December 2020

Genetics of neonatal hyperinsulinism.

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12 December 2020

Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy

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12 December 2020

Differential response of K(ATP) channels containing SUR2A or SUR2B subunits to nucleotides and pinacidil.

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12 December 2020

Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice

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12 December 2020

The common single nucleotide polymorphism E23K in K(IR)6.2 sensitizes pancreatic beta-cell ATP-sensitive potassium channels toward activation through nucleoside diphosphates

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12 December 2020

Phospholipids as modulators of K(ATP) channels: distinct mechanisms for control of sensitivity to sulphonylureas, K(+) channel openers, and ATP.

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12 December 2020

Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion

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12 December 2020

Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. A series of 175 cases

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12 December 2020

A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels

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12 December 2020

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

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12 December 2020

Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1.

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12 December 2020

Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs

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12 December 2020

Diamicron MR once daily is effective and well tolerated in type 2 diabetes: a double-blind, randomized, multinational study.

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12 December 2020

Lack of antagonism between nicorandil and sulfonylurea in stable angina pectoris.

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12 December 2020

Molecular determinants of KATP channel inhibition by ATP.

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12 December 2020

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

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12 December 2020

Interaction of sulphonylurea derivatives with vascular ATP-sensitive potassium channels in humans

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12 December 2020

Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel

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12 December 2020

Kir6.2 is required for adaptation to stress

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12 December 2020

Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart

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12 December 2020

ABC Transporters: From Microorganisms to Man

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12 December 2020

Adenine nucleotide-induced inhibition of binding of sulphonylureas to their receptor in pancreatic islets

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12 December 2020

Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding

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12 December 2020

Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels.

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12 December 2020

Sarcolemmal versus mitochondrial ATP-sensitive K+ channels and myocardial preconditioning

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12 December 2020

Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels

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12 December 2020

Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

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12 December 2020

ATP-sensitive K+ channel in the mitochondrial inner membrane

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12 December 2020

Four novel splice variants of sulfonylurea receptor 1.

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12 December 2020

Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel

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12 December 2020

Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.

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12 December 2020

Activation of stimulus-secretion coupling in pancreatic beta-cells by specific products of glucose metabolism. Evidence for privileged signaling by glycolysis.

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12 December 2020

Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose

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12 December 2020

Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels

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12 December 2020

Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

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12 December 2020

Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy

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12 December 2020

Different Binding Properties and Affinities for ATP and ADP among Sulfonylurea Receptor Subtypes, SUR1, SUR2A, and SUR2B

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12 December 2020

New windows on the mechanism of action of K(ATP) channel openers

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12 December 2020

Altered functional properties of KATP channel conferred by a novel splice variant of SUR1.

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12 December 2020

Molecular biology of adenosine triphosphate-sensitive potassium channels

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12 December 2020

Alternative splicing of sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel

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12 December 2020

Effects of nicorandil as compared to mixtures of sodium nitroprusside and levcromakalim in isolated rat aorta

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12 December 2020

Characterization of a mutant sulfonylurea receptor SUR2B with high affinity for sulfonylureas and openers: differences in the coupling to Kir6.x subtypes.

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12 December 2020

Electrophysiology of the pancreatic beta-cell

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12 December 2020

Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamido moiety, specifically inhibits pancreatic beta-cell-type K(ATP) channels

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12 December 2020

Mg2+ and ATP dependence of K(ATP) channel modulator binding to the recombinant sulphonylurea receptor, SUR2B.

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12 December 2020

Interrelationship of islet metabolism, adenosine triphosphate content and insulin release

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12 December 2020

ATP-sensitive and inwardly rectifying potassium channels in smooth muscle

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12 December 2020

Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor.

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12 December 2020

ATP-dependent potassium channels of muscle cells: their properties, regulation, and possible functions

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12 December 2020

Intracellular localization and molecular heterogeneity of the sulphonylurea receptor in insulin-secreting cells

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12 December 2020

Cloning, tissue expression, and chromosomal localization of SUR2, the putative drug-binding subunit of cardiac, skeletal muscle, and vascular KATP channels

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12 December 2020

A specific binding site for K+ channel openers in rat aorta.

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12 December 2020

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

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12 December 2020

The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation.

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12 December 2020

Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor

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12 December 2020

Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide

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12 December 2020

The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide

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12 December 2020

Glucose-receptive neurones in the rat ventromedial hypothalamus express KATP channels composed of Kir6.1 and SUR1 subunits.

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12 December 2020

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

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12 December 2020

Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP

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12 December 2020

Membrane phospholipid control of nucleotide sensitivity of KATP channels

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12 December 2020

Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels.

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12 December 2020

Sulphonylurea drugs no longer inhibit ATP-sensitive K+ channels during metabolic stress in cardiac muscle.

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12 December 2020

Genetic analysis of Japanese patients with persistent hyperinsulinemic hypoglycemia of infancy: nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1

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12 December 2020

Sulfonylurea stimulation of insulin secretion

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12 December 2020

cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets

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12 December 2020

Sulfonylurea and K(+)-channel opener sensitivity of K(ATP) channels. Functional coupling of Kir6.2 and SUR1 subunits

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12 December 2020

Differential interaction of glimepiride and glibenclamide with the beta-cell sulfonylurea receptor. I. Binding characteristics

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12 December 2020

Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide

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12 December 2020

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor

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12 December 2020

Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion

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12 December 2020

10.1007/S00125-003-1143-3

Identifiers

DOI

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6 August 2017

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