(Q35161011)

6 August 2017

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title

Ammonia neurotoxicity: role of the mitochondrial permeability transition (English)

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6 August 2017

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Rama Rao KV

1

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6 August 2017

Jayakumar AR

series ordinal

2

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6 August 2017

Norenberg DM

series ordinal

3

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6 August 2017

publication date

1 June 2003

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6 August 2017

published in

Metabolic Brain Disease

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6 August 2017

volume

18

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6 August 2017

issue

2

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6 August 2017

page(s)

113-127

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The role of glial cells in synaptic function

6 August 2017

cites work

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12 December 2020

Cerebral energy metabolism in hepatic encephalopathy and hyperammonemia

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12 December 2020

Neurosteroids and GABAA receptor function.

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12 December 2020

Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism

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12 December 2020

Oxidative stress, glutamate, and neurodegenerative disorders

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12 December 2020

The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death

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12 December 2020

Morphologic effects of ammonia on primary astrocyte cultures. II. Electron microscopic studies

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12 December 2020

Responses in primary astrocytes and C6-glioma cells to ammonium chloride and dibutyryl cyclic-AMP.

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12 December 2020

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

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12 December 2020

Progressive decrease of cerebral cytochrome C oxidase activity in sparse-fur mice: role of acetyl-L-carnitine in restoring the ammonia-induced cerebral energy depletion.

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12 December 2020

Synaptic transmission in ammonia intoxication

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12 December 2020

Mitochondrial benzodiazepine receptor linked to inner membrane ion channels by nanomolar actions of ligands

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12 December 2020

Neurotoxicity of ammonia and glutamate: molecular mechanisms and prevention.

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12 December 2020

Mitochondrial calcium transport: physiological and pathological relevance

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12 December 2020

Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate

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12 December 2020

Ammonia-induced production of free radicals in primary cultures of rat astrocytes

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12 December 2020

Effect of antioxidants on ammonia induced CNS-renal pathobiology in sheep.

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12 December 2020

Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells

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12 December 2020

Neuron-specific mitochondrial degeneration induced by hyperammonemia and octanoic acidemia.

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12 December 2020

The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition

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12 December 2020

Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis

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12 December 2020

Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats

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12 December 2020

Reactive oxygen species and the central nervous system

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12 December 2020

Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria

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12 December 2020

Hepatic encephalopathy

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12 December 2020

The mitochondrial permeability transition

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12 December 2020

Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore

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12 December 2020

Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis

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12 December 2020

The astrocytic ("peripheral-type") benzodiazepine receptor: role in the pathogenesis of portal-systemic encephalopathy

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12 December 2020

Intracellular pH rises and astrocytes swell after portacaval anastomosis in rats

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12 December 2020

The mitochondrial permeability transition.

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12 December 2020

Hyperammonaemia does not impair brain function in the absence of net glutamine synthesis

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12 December 2020

Restoration of cerebrovascular CO2 responsivity by glutamine synthesis inhibition in hyperammonemic rats

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12 December 2020

Induction of the mitochondrial permeability transition in cultured astrocytes by glutamine

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12 December 2020

Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat

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12 December 2020

Biochemistry and physiology of brain ammonia

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12 December 2020

The role of astrocytes in hepatic encephalopathy

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12 December 2020

Differential inhibition by hyperammonemia of the electron transport chain enzymes in synaptosomes and non-synaptic mitochondria in ornithine transcarbamylase-deficient spf-mice: restoration by acetyl-L-carnitine.

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12 December 2020

Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice.

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12 December 2020

Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes

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12 December 2020

Electron microscopy in human hepatic encephalopathy

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12 December 2020

Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

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12 December 2020

The mitochondrial death/life regulator in apoptosis and necrosis

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12 December 2020

Molecular mechanism of acute ammonia toxicity and of its prevention by L-carnitine

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12 December 2020

Neurology and the liver

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12 December 2020

Ammonia induces the mitochondrial permeability transition in primary cultures of rat astrocytes

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12 December 2020

The glial glutamate transporter in hyperammonemia and hepatic encephalopathy: relation to energy metabolism and glutamatergic neurotransmission.

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12 December 2020

A light and electron microscopic study of experimental portal-systemic (ammonia) encephalopathy. Progression and reversal of the disorder

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12 December 2020

The relationship between mitochondrial membrane permeability, membrane potential, and the retention of Ca2+ by mitochondria

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12 December 2020

Astrocyte swelling in liver failure: role of glutamine and benzodiazepines

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12 December 2020

Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration

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12 December 2020

Effect of ammonium chloride on energy metabolism of astrocytes and C6-glioma cells in vitro.

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12 December 2020

Current theories on the pathogenesis of hepatic encephalopathy

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12 December 2020

Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells

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12 December 2020

Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.

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12 December 2020

Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

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12 December 2020

Ammonia and manganese increase arginine uptake in cultured astrocytes.

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12 December 2020

Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis

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12 December 2020

The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site

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12 December 2020

Cellular bases of brain energy metabolism and their relevance to functional brain imaging: evidence for a prominent role of astrocytes.

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12 December 2020

Changes in brain metabolism in hepatic encephalopathy

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12 December 2020

Superoxide production and antioxidant enzymes in ammonia intoxication in rats.

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12 December 2020

1 reference

12 December 2020

The peripheral benzodiazepine receptor and neurosteroids in hepatic encephalopathy.

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12 December 2020

Effects of ammonia and beta-methylene-DL-aspartate on the oxidation of glucose and pyruvate by neurons and astrocytes in primary culture

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12 December 2020

Liver transplantation in Europe for patients with acute liver failure.

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12 December 2020

Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication

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12 December 2020

Oxidative and nitrosative stress in ammonia neurotoxicity

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12 December 2020

Delayed induction of apoptosis by ammonia in C6 glioma cells

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12 December 2020

Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: effects of in vitro treatment with ammonia, hyperammonemia and hepatic encephalopathy.

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12 December 2020

Pyruvate decarboxylation in astrocytes and in neurons in primary cultures in the presence and the absence of ammonia

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12 December 2020

Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy

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12 December 2020

Nitroarginine, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication.

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12 December 2020

Hepatic encephalopathy: An update of pathophysiologic mechanisms

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12 December 2020

The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure

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12 December 2020

Tripartite synapses: glia, the unacknowledged partner

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12 December 2020

Mechanisms by which mitochondria transport calcium

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12 December 2020

Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts

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12 December 2020

Pathogenesis of hepatic encephalopathy

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12 December 2020

Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria.

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12 December 2020

Induction of permeability transition and swelling of rat brain mitochondria by glutamine

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12 December 2020

Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo

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12 December 2020

Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: ultrastructure and integrity of the blood-brain barrier

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12 December 2020

Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors

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12 December 2020

Fulminant hepatic failure. Clinical features, etiology, epidemiology, and current management

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12 December 2020

Morphologic effects of ammonia on primary astrocyte cultures. I. Light microscopic studies

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12 December 2020

Activities of pyruvate dehydrogenase, enzymes of citric acid cycle, and aminotransferases in the subcellular fractions of cerebral cortex in normal and hyperammonemic rats.

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12 December 2020

Identifiers

DOI

10.1023/A:1023858902184

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Dimensions Publication ID

6 August 2017

1022945563

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