(Q35161580)

6 August 2017

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title

Mitochondrion-mediated apoptosis in HIV-1 infection (English)

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6 August 2017

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1

Andrew D Badley

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6 August 2017

4

Guido Kroemer

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6 August 2017

Thomas Roumier

2

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6 August 2017

Julian J Lum

series ordinal

3

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6 August 2017

publication date

1 June 2003

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Trends in Pharmacological Sciences

6 August 2017

published in

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6 August 2017

volume

24

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6 August 2017

issue

6

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6 August 2017

page(s)

298-305

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Organelle-specific initiation of cell death pathways

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Mitochondrial control of cell death

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Apoptosis: mitochondrial membrane permeabilization--the (w)hole story?

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7 January 2021

Programmed cell death as a mechanism of CD4 and CD8 T cell deletion in AIDS. Molecular control and effect of highly active anti-retroviral therapy

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7 January 2021

Chronic elevation of plasma thioredoxin: inhibition of chemotaxis and curtailment of life expectancy in AIDS

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7 January 2021

Cell-Surface-Expressed HIV-1 Envelope Induces the Death of CD4 T Cells during GP41-Mediated Hemifusion-like Events

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

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7 January 2021

Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

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7 January 2021

The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway

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7 January 2021

Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation

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7 January 2021

Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways

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7 January 2021

Binding of human immunodeficiency virus type 1 gp120 to CXCR4 induces mitochondrial transmembrane depolarization and cytochrome c-mediated apoptosis independently of Fas signaling

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.

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7 January 2021

T Cell Apoptosis Causes Peripheral T Cell Depletion in Mice Transgenic for the HIV-1 vpr Gene

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Programmed death of T cells in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Abnormal intracellular kinetics of cell-cycle-dependent proteins in lymphocytes from patients infected with human immunodeficiency virus: a novel biologic link between immune activation, accelerated T-cell turnover, and high levels of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Apoptosis and apoptosis-associated perturbations of peripheral blood lymphocytes during HIV infection: comparison between AIDS patients and asymptomatic long-term non-progressors.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV-infected long-term nonprogressors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Genetic characterization of vif, vpr, and vpu sequences from long-term survivors of human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Evidence for a cytopathogenicity determinant in HIV-1 Vpr.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Mitochondrion-targeted apoptosis regulators of viral origin.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Decreased HIV-associated T cell apoptosis by HIV protease inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Reduced levels of CD4 cell spontaneous apoptosis in human immunodeficiency virus-infected patients with discordant response to protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Discordant CD4 T lymphocyte responses to antiretroviral therapy for HIV infection are associated with ex-vivo rates of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Long-term clinical outcome of human immunodeficiency virus-infected patients with discordant immunologic and virologic responses to a protease inhibitor-containing regimen

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

"Discordant" increases in CD4 cell count relative to plasma viral load in a closely followed cohort of patients initiating antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Reduction in T cell apoptosis in patients with HIV disease following antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Ex vivo and in vitro effect of human immunodeficiency virus protease inhibitors on neutrophil apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

The HIV protease inhibitor Indinavir inhibits cell-cycle progression in vitro in lymphocytes of HIV-infected and uninfected individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors: a looming obstacle for long-term antiretroviral therapy?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Accumulation of mitochondrial DNA mutations in human immunodeficiency virus-infected patients treated with nucleoside-analogue reverse-transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Mechanisms of toxicity of 3'-azido-3'-deoxythymidine. Its interaction with adenylate kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Inhibition of nucleoside diphosphate kinase in rat liver mitochondria by added 3′-azido-3′-deoxythymidine

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Induction of apoptosis by a nonnucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Prognosis in AZT myopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

AZT myopathy and HIV-1 polymyositis: one disease or two?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Molecular mechanism of the short-term cardiotoxicity caused by 2',3'-dideoxycytidine (ddC): modulation of reactive oxygen species levels and ADP-ribosylation reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Hyperlactatemia syndromes in people with HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Evidence of nucleoside analogue reverse transcriptase inhibitor--associated genetic and structural defects of mitochondria in adipose tissue of HIV-infected patients

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Fat distribution evaluated by computed tomography and metabolic abnormalities in patients undergoing antiretroviral therapy: preliminary results of the LIPOCO study.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Interference with cell cycle progression and induction of apoptosis by dideoxynucleoside analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Stavudine selectively induces apoptosis in HIV type 1-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

Benign symmetric lipomatosis associated with protease inhibitors

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https://api.crossref.org/works/10.1016%2FS0165-6147%2803%2900125-1

7 January 2021

10.1016/S0165-6147(03)00125-1

Identifiers

DOI

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6 August 2017

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