(Q35162837)

6 August 2017

title

Correlated motion and the effect of distal mutations in dihydrofolate reductase (English)

1 reference

6 August 2017

Thomas H Rod

1

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6 August 2017

Jennifer L Radkiewicz

series ordinal

2

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6 August 2017

Charles L Brooks

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

19 May 2003

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

100

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6 August 2017

issue

12

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6 August 2017

page(s)

6980-6985

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Impact of enzyme motion on activity

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Network of coupled promoting motions in enzyme catalysis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Stretching exercises--flexibility in dihydrofolate reductase catalysis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165816

Dynamics of a flexible loop in dihydrofolate reductase from Escherichia coli and its implication for catalysis.

13 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

Identification of a protein-promoting vibration in the reaction catalyzed by horse liver alcohol dehydrogenase

21 January 2018

1 reference

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ART 2: self-organization of stable category recognition codes for analog input patterns.

21 January 2018

1 reference

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Statistical clustering techniques for the analysis of long molecular dynamics trajectories: analysis of 2.2-ns trajectories of YPGDV.

21 January 2018

1 reference

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A major role for a set of non-active site mutations in the development of HIV-1 protease drug resistance

21 January 2018

1 reference

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

Dihydrofolate reductase from Escherichia coli: probing the role of aspartate-27 and phenylalanine-137 in enzyme conformation and the binding of NADPH

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

A kinetic study of wild-type and mutant dihydrofolate reductases from Lactobacillus casei

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

Nonadditive effects of double mutations at the flexible loops, glycine-67 and glycine-121, of Escherichia coli dihydrofolate reductase on its stability and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

Novel generalized Born methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1230801100

21 January 2018

Identifiers

DOI

10.1073/PNAS.1230801100

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6 August 2017

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6 August 2017

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