(Q35164422)

6 August 2017

title

Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome (English)

1 reference

Chlamydia pneumoniae infection

6 August 2017

1 reference

1 reference

Chlamydia pneumoniae

1 reference

5

Egil Lien

1 reference

6 August 2017

Xianbao He

1

1 reference

6 August 2017

Samrawit Mekasha

2

1 reference

6 August 2017

Nikolaos Mavrogiorgos

3

1 reference

6 August 2017

Katherine A Fitzgerald

4

1 reference

6 August 2017

Robin R Ingalls

6

1 reference

6 August 2017

language of work or name

English

0 references

publication date

14 April 2010

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6 August 2017

published in

Journal of Immunology

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6 August 2017

volume

184

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6 August 2017

issue

10

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6 August 2017

page(s)

5743-5754

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Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases

6 August 2017

cites work

1 reference

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13 July 2018

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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

13 July 2018

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An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans

13 July 2018

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Chlamydial heat shock protein 60 induces acute pulmonary inflammation in mice via the Toll-like receptor 4- and MyD88-dependent pathway

13 July 2018

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The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

13 July 2018

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The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.

13 July 2018

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The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection

13 July 2018

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Inflammasome recognition of influenza virus is essential for adaptive immune responses

13 July 2018

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

13 July 2018

1 reference

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

13 July 2018

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

13 July 2018

1 reference

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

13 July 2018

1 reference

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Active caspase-1 is a regulator of unconventional protein secretion

13 July 2018

1 reference

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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

13 July 2018

1 reference

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In vivo and in vitro effects of salbutamol on alveolar epithelial repair in acute lung injury

13 July 2018

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Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle

13 July 2018

1 reference

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

13 July 2018

1 reference

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Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf.

13 July 2018

1 reference

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Intracellular pattern recognition receptors in the host response

13 July 2018

1 reference

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Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae

13 July 2018

1 reference

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The P2X7 receptor: a key player in IL-1 processing and release

13 July 2018

1 reference

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Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Cryopyrin activates the inflammasome in response to toxins and ATP

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Gout-associated uric acid crystals activate the NALP3 inflammasome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

13 July 2018

1 reference

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Toll-like receptor 2 mediates persistent chemokine release by Chlamydia pneumoniae-infected vascular smooth muscle cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia

13 July 2018

1 reference

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Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae

13 July 2018

1 reference

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Toll-like receptors 2 and 4 do not contribute to clearance of Chlamydophila pneumoniae in mice, but are necessary for the release of monokines

13 July 2018

1 reference

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Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

13 July 2018

1 reference

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Neutrophils in asthma pathophysiology

13 July 2018

1 reference

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Role of the neutrophil in septic shock and the adult respiratory distress syndrome

13 July 2018

1 reference

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The chlamydial inclusion: escape from the endocytic pathway.

13 July 2018

1 reference

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Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Predominant role of toll-like receptor 2 versus 4 in Chlamydia pneumoniae-induced activation of dendritic cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Chlamydia pneumoniae and chlamydial heat shock protein 60 stimulate proliferation of human vascular smooth muscle cells via toll-like receptor 4 and p44/p42 mitogen-activated protein kinase activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1beta-dependent mechanism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Altered cytokine production in mice lacking P2X(7) receptors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Impaired wound healing in embryonic and adult mice lacking vimentin.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Background and current knowledge of Chlamydia pneumoniae and atherosclerosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Enhanced Th2-like responses in IL-1 type 1 receptor-deficient mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Isolation of Chlamydia pneumoniae from the coronary artery of a patient with coronary atherosclerosis. The Chlamydia pneumoniae/Atherosclerosis Study Group

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Characterization of murine lung interstitial macrophages in comparison with alveolar macrophages in vitro.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Biologic basis for interleukin-1 in disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Application of a Mycoplasma group-specific PCR for monitoring decontamination of Mycoplasma-infected Chlamydia sp. strains

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Adult respiratory distress syndrome in patients with severe neutropenia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

A new Chlamydia psittaci strain, TWAR, isolated in acute respiratory tract infections

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Endotoxin-induced cytokine gene expression in vivo. IV. Expression of interleukin-1 alpha/beta and interleukin-1 receptor antagonist mRNA during endotoxemia and during endotoxin-initiated local acute inflammation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

IL1 may be elevated but is it all bad in ARDS?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Interleukin-1beta augments in vitro alveolar epithelial repair

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156096

Type I IL-1 receptor blockade exacerbates murine listeriosis

16 November 2018

1 reference

12 December 2020

Compartmentalized cytokine production within the human lung in unilateral pneumonia

1 reference

12 December 2020

Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1

1 reference

12 December 2020

Interleukin-12: a cytokine at the interface of inflammation and immunity

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0903937

1 reference

6 August 2017

1 reference

6 August 2017

1 reference