(Q35164861)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Systemic augmentation of alphaB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

9

Gary K Steinberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Ahmet Arac

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Sara E Brownell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jonathan B Rothbard

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Charlene Chen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Rose M Ko

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Gregory W Albers

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Lawrence Steinman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

26 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

13287-13292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

Stroke and the immune system: from pathophysiology to new therapeutic strategies

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Fingolimod provides long-term protection in rodent models of cerebral ischemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Long-term behavioral assessment of function in an experimental model for ischemic stroke

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Degeneration and repair in central nervous system disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

The science of stroke: mechanisms in search of treatments

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Discriminative capacity of biomarkers for acute stroke in the emergency department

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Infarct volume is a major determiner of post-stroke immune cell function and susceptibility to infection.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Interleukin-17 causes neutrophil mediated inflammation in ovalbumin-induced uveitis in DO11.10 mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Changes in experimental stroke outcome across the life span

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

A new penumbra: transitioning from injury into repair after stroke

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Pathophysiology and therapy of experimental stroke

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Mechanisms, challenges and opportunities in stroke

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Differential expression of small heat shock proteins in reactive astrocytes after focal ischemia: possible role of beta-adrenergic receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156222

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Functional rescue of experimental ischemic optic neuropathy with αB-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Adoptive transfer of myelin basic protein-tolerized splenocytes to naive animals reduces infarct size: a role for lymphocytes in ischemic brain injury?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

The spectrum of systemic immune alterations after murine focal ischemia: immunodepression versus immunomodulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Monocyte subtypes predict clinical course and prognosis in human stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Co-induction of alphaB-crystallin and MAPKAPK-2 in astrocytes in the penumbra after transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Tissue plasminogen activator and plasminogen activator inhibitor-1 in stroke patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Recombinant C1 inhibitor in brain ischemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Induction of mucosal tolerance to E-selectin prevents ischemic and hemorrhagic stroke in spontaneously hypertensive genetically stroke-prone rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

Inhibitory role for GABA in autoimmune inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

The small heat-shock protein αB-crystallin as candidate autoantigen in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1107368108

21 January 2018

Assault on the guardian

1 reference

12 December 2020

An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment

1 reference

12 December 2020

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

1 reference

12 December 2020

Neuronal expression of αB crystallin in cerebral infarction

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1107368108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

release_ve4qivmuyrhx5o4hw7wj2q3f7y

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ve4qivmuyrhx5o4hw7wj2q3f7y

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21828004%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

21828004

1 reference