(Q35165719)

6 August 2017

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title

Gene therapy progress and prospects: adenoviral vectors (English)

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6 August 2017

0 references

1 reference

St George JA

1

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6 August 2017

publication date

1 July 2003

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6 August 2017

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6 August 2017

volume

10

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6 August 2017

issue

14

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6 August 2017

page(s)

1135-1141

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302071

6 August 2017

exact match

0 references

cites work

Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

The release of inflammatory cytokines from human peripheral blood mononuclear cells in vitro following exposure to adenovirus variants and capsid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Complement activation by recombinant adenoviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Recombinant adenovirus induces maturation of dendritic cells via an NF-kappaB-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Adenoviral vectors do not induce, inhibit, or potentiate human platelet aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Toxicity of a first-generation adenoviral vector in rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Budesonide enhances repeated gene transfer and expression in the lung with adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Ligand-directed targeting of genes to the site of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Genetic targeting of adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Pseudopackaging of adenovirus type 5 genomes into capsids containing the hexon proteins of adenovirus serotypes B, D, or E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A genetically modified adenoviral vector exhibits enhanced gene transfer of human smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Ovine adenovirus vectors mediate efficient gene transfer to skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Genetic retargeting of adenovirus: novel strategy employing "deknobbing" of the fiber

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Recombinant adenovirus vectors with knobless fibers for targeted gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Targeted adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Recombinant human adenovirus: targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A tropism-modified adenoviral vector increased the effectiveness of gene therapy for arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Targeting of high-capacity adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Localized adenovirus gene delivery using antiviral IgG complexation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Enhancement of adenovirus vector entry into CD70-positive B-cell Lines by using a bispecific CD70-adenovirus fiber antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Dual targeting of adenoviral vectors at the levels of transduction and transcription enhances the specificity of gene expression in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Immune evasion by muscle-specific gene expression in dystrophic muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

In vivo hepatic adenoviral gene delivery occurs independently of the coxsackievirus-adenovirus receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Long-term efficacy after [E1-, polymerase-] adenovirus-mediated transfer of human acid-alpha-glucosidase gene into glycogen storage disease type II knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Generation and characterization of E1/E2a/E3/E4-deficient adenoviral vectors encoding human factor VIII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Induction of cell death by adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Molecular regulation and biological function of adenovirus early genes: the E4 ORFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A new vector system with inducible E2a cell line for production of higher titer and safer adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Development of a FLP/frt system for generating helper-dependent adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Sustained human factor VIII expression in hemophilia A mice following systemic delivery of a gutless adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Optimization of the generation and propagation of gutless adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Effective repeat administration with adenovirus vectors to the muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A phase I/II trial of rAd/p53 (SCH 58500) gene replacement in recurrent ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Circumvention of vector-specific neutralizing antibody response by alternating use of human and non-human adenoviruses: implications in gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Specific depletion of human anti-adenovirus antibodies facilitates transduction in an in vivo model for systemic gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Transient blocking of both B7.1 (CD80) and B7.2 (CD86) in addition to CD40-CD40L interaction fully abrogates the immune response following systemic injection of adenovirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Systemic delivery of a high-capacity adenoviral vector expressing mouse CTLA4Ig improves skeletal muscle gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Local high-capacity adenovirus-mediated mCTLA4Ig and mCD40Ig expression prolongs recombinant gene expression in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

Assessment of adenoviral vector safety and toxicity: report of the National Institutes of Health Recombinant DNA Advisory Committee

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

inferred from DOI database lookup

7 January 2021

based on heuristic

Adenoviral vectors--new insights

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

inferred from DOI database lookup

7 January 2021

based on heuristic

Sustained expression of human apolipoprotein A-I after adenoviral gene transfer in C57BL/6 mice: role of apolipoprotein A-I promoter, apolipoprotein A-I introns, and human apolipoprotein E enhancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302071

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.GT.3302071

1 reference

6 August 2017

1 reference