(Q35168503)

English

Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol (English)

1 reference

Europe PubMed Central

6 August 2017

Amy Hauck Newman

6

object named as

Amy Hauck Newman

1 reference

Europe PubMed Central

6 August 2017

Jeffrey R. Deschamps

4

object named as

Jeffrey R Deschamps

1 reference

Europe PubMed Central

6 August 2017

author name string

Noel M Paul

1

1 reference

Europe PubMed Central

6 August 2017

Michelle Taylor

2

1 reference

Europe PubMed Central

6 August 2017

Rakesh Kumar

3

1 reference

Europe PubMed Central

6 August 2017

Robert R Luedtke

5

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

6 September 2008

1 reference

Europe PubMed Central

6 August 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

6 August 2017

51

1 reference

Europe PubMed Central

6 August 2017

19

1 reference

Europe PubMed Central

6 August 2017

6095-6109

1 reference

Europe PubMed Central

6 August 2017

Antipsychotic safety and efficacy concerns

1 reference

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13 July 2018

Evolution of schizophrenia drugs: a focus on dopaminergic systems.

1 reference

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13 July 2018

Dopamine in drug abuse and addiction: results of imaging studies and treatment implications

1 reference

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13 July 2018

Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile

1 reference

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13 July 2018

Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents

1 reference

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13 July 2018

Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction

1 reference

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13 July 2018

New developments in the pharmacotherapy of cocaine abuse

1 reference

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13 July 2018

Dopamine D3 receptor ligands for the treatment of tobacco dependence

1 reference

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13 July 2018

Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR

1 reference

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13 July 2018

Multifunctional drugs with different CNS targets for neuropsychiatric disorders

1 reference

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13 July 2018

The structural evolution of dopamine D3 receptor ligands: structure-activity relationships and selected neuropharmacological aspects

1 reference

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13 July 2018

I want a new drug: G-protein-coupled receptors in drug development

1 reference

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13 July 2018

Synthesis and characterization of selective dopamine D2 receptor antagonists.

1 reference

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13 July 2018

Designed multiple ligands. An emerging drug discovery paradigm

1 reference

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13 July 2018

Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents

1 reference

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13 July 2018

The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats

1 reference

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13 July 2018

Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor

1 reference

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13 July 2018

Dopamine in drug abuse and addiction: results from imaging studies and treatment implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

1 reference

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13 July 2018

N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

Novel tropane-based irreversible ligands for the dopamine transporter

1 reference

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13 July 2018

Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors

1 reference

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13 July 2018

Haloperidol-induced catalepsy is absent in dopamine D(2), but maintained in dopamine D(3) receptor knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

Imaging studies on the role of dopamine in cocaine reinforcement and addiction in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

Prediction of reinforcing responses to psychostimulants in humans by brain dopamine D2 receptor levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

Molecular diversity of the dopamine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines

1 reference

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13 July 2018

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

13 July 2018

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: I. Receptor-binding profile and functio

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiologic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

Towards a new generation of potential antipsychotic agents combining D2 and 5-HT1A receptor activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

Effects of two novel D3-selective compounds, NGB 2904 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide] and CJB 090 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-4-(pyridin-2-yl)benzamide], on the reinforcing and dis

1 reference

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27 September 2018

Effects of RGH-237 [N-{4-[4-(3-aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an orally active, selective dopamine D(3) receptor partial agonist in animal models of cocaine abuse.

1 reference

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27 September 2018

Studies towards the identification of a new generation of atypical antipsychotic agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys.

1 reference

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27 September 2018

Haloperidol: towards further understanding of the structural contributions of its pharmacophoric elements at D2-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

Modulation of selective serotonin reuptake inhibitor and 5-HT1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

The acute EPS of haloperidol may be unrelated to its metabolic transformation to BCPP +

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

Design and synthesis of [(2,3-dichlorophenyl)piperazin-1-yl]alkylfluorenylcarboxamides as novel ligands selective for the dopamine D3 receptor subtype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157365

27 September 2018

S33138 (N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenyl-acetamide), a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: III. Actions in models of therapeutic

1 reference

https://pubmed.ncbi.nlm.nih.gov/18774793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probing structure of neurotransmitter transporters by substituted-cysteine accessibility method

1 reference

https://pubmed.ncbi.nlm.nih.gov/18774793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/18774793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM800532X

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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