(Q35169985)

6 August 2017

1 reference

title

Shutdown of translation: lethal or protective? Unfolded protein response versus apoptosis (English)

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6 August 2017

1 reference

Wulf Paschen

1

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6 August 2017

1 July 2003

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Journal of Cerebral Blood Flow & Metabolism

6 August 2017

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6 August 2017

23

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6 August 2017

7

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6 August 2017

773-779

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https://scigraph.springernature.com/pub.10.1097/01.wcb.0000075009.47474.f9

6 August 2017

0 references

cites work

Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice.

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Selective proteasomal dysfunction in the hippocampal CA1 region after transient forebrain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Neuronal calcium signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Cerebral protein synthesis and ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Phosphorylation of the alpha subunit of initiation factor 2 correlates with the inhibition of translation following transient cerebral ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

The effect of ischaemia and recirculation on protein synthesis in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Relation of neuronal endoplasmic reticulum calcium homeostasis to ribosomal aggregation and protein synthesis: implications for stress-induced suppression of protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Activation of MYD116 (gadd34) expression following transient forebrain ischemia of rat: implications for a role of disturbances of endoplasmic reticulum calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Activation of heme oxygenase-1 expression by disturbance of endoplasmic reticulum calcium homeostasis in rat neuronal cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Programmed cell death in cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Endoplasmic reticulum stress and the development of diabetes: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Differential induction of mRNA species encoding several classes of stress proteins following focal cerebral ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Technique for in situ measurement of calcium in intracellular inositol 1,4,5-trisphosphate-sensitive stores using the fluorescent indicator mag-fura-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Protein aggregation after focal brain ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

1 reference

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Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Role of calcium in the activation of erp72 and heme oxygenase-1 expression on depletion of endoplasmic reticulum calcium stores in rat neuronal cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Apoptosis after experimental stroke: fact or fashion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Mechanisms underlying suppression of protein synthesis induced by transient focal cerebral ischemia in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Erp72 expression activated by transient cerebral ischemia or disturbance of neuronal endoplasmic reticulum calcium stores.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Activation of the double-stranded RNA-regulated protein kinase by depletion of endoplasmic reticular calcium stores

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Calcium depletion from the endoplasmic reticulum activates the double-stranded RNA-dependent protein kinase (PKR) to inhibit protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Persistent inhibition of protein synthesis precedes delayed neuronal death in postischemic gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

Induction of glucose regulated protein (grp78) and inducible heat shock protein (hsp70) mRNAs in rat brain after kainic acid seizures and focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000075009.47474.F9

10.1097/01.WCB.0000075009.47474.F9

21 January 2018

Identifiers

DOI

1 reference

PubMed ID

12843781

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12843781