(Q35170270)

6 August 2017

title

A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes (English)

1 reference

6 August 2017

2

George S Eisenbarth

1 reference

6 August 2017

John C Hutton

1

1 reference

6 August 2017

language of work or name

English

0 references

publication date

14 July 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

100

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6 August 2017

issue

15

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6 August 2017

page(s)

8626-8628

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Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

T cell response to preproinsulin I and II in the nonobese diabetic mouse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Development of autoimmunity in Lyme arthritis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Characterization of the mouse islet-specific glucose-6-phosphatase catalytic subunit-related protein gene promoter by in situ footprinting: correlation with fusion gene expression in the islet-derived betaTC-3 and hamster insulinoma tumor cell lines

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.

13 July 2018

1 reference

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Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

T cell receptor restriction of diabetogenic autoimmune NOD T cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Diabetogenic T-cell clones

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

A subtractive cloning approach to the identification of mRNAs specifically expressed in pancreatic beta-cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Analysis of the spontaneous T cell response to insulin in NOD mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Genetic control of autoimmune diabetes in the NOD mouse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

T-lymphocyte clone specific for pancreatic islet antigen

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

NIT-1, a Pancreatic β-Cell Line Established From a Transgenic NOD/Lt Mouse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166361

T-cell epitope analysis on the autoantigen phogrin (IA-2beta) in the nonobese diabetic mouse

13 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1633447100

Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1633447100

Expansion of the Antigenic Repertoire of a Single T Cell Receptor upon T Cell Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1633447100

Transient insulin autoantibody expression independent of development of diabetes: comparison of NOD and NOR strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1633447100

Generation and maintenance of autoantigen-specific CD8(+) T cell clones isolated from NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1633447100

21 January 2018

Identifiers

DOI

10.1073/PNAS.1633447100

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference