(Q35173044)

English

Short term exposure of beta cells to low concentrations of interleukin-1β improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression.

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25586177%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Short term exposure of beta cells to low concentrations of interleukin-1β improves insulin secretion through focal adhesion and actin remodeling and regulation of gene expression (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25586177%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Pedro G. Ferreira

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25586177%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Caroline Arous

1

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27 February 2020

Emmanouil T Dermitzakis

3

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25586177%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Philippe A Halban

4

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27 February 2020

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13 January 2015

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27 February 2020

Journal of Biological Chemistry

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27 February 2020

290

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27 February 2020

10

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27 February 2020

6653-6669

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Europe PubMed Central

PMC publication ID

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27 February 2020

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4358297/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Targeting inflammation in the treatment of type 2 diabetes: time to start

1 reference

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Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

1 reference

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13 July 2018

Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion

1 reference

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13 July 2018

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1 reference

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1 reference

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13 July 2018

IL-1β enhances cell adhesion to degraded fibronectin.

1 reference

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1 reference

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13 July 2018

Actin cytoskeleton modulates ADMA-induced NF-kappaB nuclear translocation and ICAM-1 expression in endothelial cells

1 reference

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13 July 2018

High-resolution quantification of focal adhesion spatiotemporal dynamics in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Focal adhesions and Ras are functionally and spatially integrated to mediate IL-1 activation of ERK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Crosstalk of reactive oxygen species and NF-κB signaling

1 reference

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13 July 2018

STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Actin cytoskeleton participation in the onset of IL-1beta induction of an invasive mesenchymal-like phenotype in epithelial MCF-7 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

1 reference

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13 July 2018

Electrophysiology of islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Blockade of interleukin 1 in type 1 diabetes mellitus

1 reference

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13 July 2018

Cytokine production by islets in health and diabetes: cellular origin, regulation and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Interleukin-1 (IL-1) pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

The NF-kappaB family of transcription factors and its regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion

1 reference

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13 July 2018

JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues

1 reference

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13 July 2018

Perturbation of actin dynamics induces NF-kappaB activation in myelomonocytic cells through an NADPH oxidase-dependent pathway

1 reference

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13 July 2018

Oscillations in NF-kappaB signaling control the dynamics of gene expression

1 reference

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13 July 2018

Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

1 reference

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13 July 2018

JNK phosphorylates paxillin and regulates cell migration

1 reference

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13 July 2018

Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix

1 reference

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13 July 2018

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

1 reference

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13 July 2018

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

1 reference

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13 July 2018

Paxillin: a focal adhesion-associated adaptor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix

1 reference

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13 July 2018

Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observations

1 reference

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13 July 2018

Tolbutamide and diazoxide influence insulin secretion by changing the concentration but not the action of cytoplasmic Ca2+ in beta-cells.

1 reference

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13 July 2018

Biologic basis for interleukin-1 in disease

1 reference

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13 July 2018

PACE4: a subtilisin-like endoprotease prevalent in the anterior pituitary and regulated by thyroid status

1 reference

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13 July 2018

Interleukin 1 is potent modulator of insulin secretion from isolated rat islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Descriptive and mechanistic considerations of interleukin 1 and insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Human interleukin 1 beta stimulates islet insulin release by a mechanism not dependent on changes in phospholipase C and protein kinase C activities or Ca2+ handling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Interleukin 1 is a potent stimulator of islet insulin secretion and phosphoinositide hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

13 July 2018

Role of actin cytoskeleton in LPS-induced NF-kappaB activation and nitric oxide production in murine macrophages

1 reference

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27 September 2018

Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

27 September 2018

Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

27 September 2018

Activation of NF-kappaB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

27 September 2018

Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

27 September 2018

A biphasic role of nuclear transcription factor (NF)-kappaB in the islet beta-cell apoptosis induced by interleukin (IL)-1beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

27 September 2018

Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

27 September 2018

Glucose regulates the cortical actin network through modulation of Cdc42 cycling to stimulate insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358297

27 September 2018

Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex

1 reference

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27 September 2018

The mechanism of diamond nucleation from energetic species.

1 reference

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27 September 2018

Short-term exposure of rat pancreatic islets to human interleukin-1 beta increases cellular uptake of calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The recruitment of the interleukin-1 (IL-1) receptor-associated kinase (IRAK) into focal adhesion complexes is required for IL-1beta -induced ERK activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pancreatic -cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human interleukin-1 beta induced stimulation of insulin release from rat pancreatic islets is accompanied by an increase in mitochondrial oxidative events

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominance of stimulatory effects of interleukin-1 beta on isolated human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/25586177

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.611111

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25586177%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25586177%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25586177%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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