(Q37696271)

22 August 2017

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title

Blockade of interleukin 1 in type 1 diabetes mellitus (English)

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22 August 2017

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Thomas Mandrup-Poulsen

object named as

Thomas Mandrup-Poulsen

series ordinal

1

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author name string

Linda Pickersgill

series ordinal

2

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22 August 2017

Marc Yves Donath

series ordinal

3

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22 August 2017

publication date

1 March 2010

1 reference

Nature Reviews Endocrinology

22 August 2017

published in

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22 August 2017

volume

6

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22 August 2017

issue

3

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22 August 2017

page(s)

158-166

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https://scigraph.springernature.com/pub.10.1038/nrendo.2009.271

22 August 2017

exact match

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cites work

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The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

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Monokine-producing cells predominate in the recruitment phase of NOD insulitis while cells producing Th1-type cytokines characterize the effector phase

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Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.

31 March 2020

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Immunological and inflammatory functions of the interleukin-1 family

31 March 2020

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Potential therapeutic uses of interleukin 1 receptor antagonists in human diseases

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The role of interleukin-1 in disease

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Five-year follow-up after clinical islet transplantation

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A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

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Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

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GAD treatment and insulin secretion in recent-onset type 1 diabetes

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Effects of insulin in relatives of patients with type 1 diabetes mellitus

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Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I.

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Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets

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Endotoxin-induced hyperinsulinemia and hyperglucagonemia after experimental liver injury.

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Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation

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The Fas pathway is involved in pancreatic beta cell secretory function

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Cytokines and beta-cell biology: from concept to clinical translation

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Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

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Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases

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Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity

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Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells

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Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt.

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Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

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Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction

31 March 2020

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Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells.

31 March 2020

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Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells

31 March 2020

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Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells

31 March 2020

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Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

31 March 2020

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The BCL-2 protein family: opposing activities that mediate cell death

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

31 March 2020

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31 March 2020

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IL-1 receptor deficiency slows progression to diabetes in the NOD mouse

31 March 2020

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Caspase-1 is not required for type 1 diabetes in the NOD mouse

31 March 2020

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Changing Prevalence of Overweight Children and Adolescents at Onset of Insulin-Treated Diabetes

31 March 2020

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31 March 2020

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Monokine Antagonism Is Reduced in Patients With IDDM

31 March 2020

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31 March 2020

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Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets

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31 March 2020

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IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat

31 March 2020

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Use of canakinumab in the cryopyrin-associated periodic syndrome

31 March 2020

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Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies

31 March 2020

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The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study

31 March 2020

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The future of the IL-1 receptor antagonist anakinra: from rheumatoid arthritis to adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis

31 March 2020

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Rapid responses to anakinra in patients with refractory adult-onset Still's disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2009.271

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

31 March 2020

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31 March 2020

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31 March 2020

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Islet inflammation in type 2 diabetes: from metabolic stress to therapy.

31 March 2020

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Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2009.271

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2009.271

Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

31 March 2020

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Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra

31 March 2020

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A pilot study of IL-1 inhibition by anakinra in acute gout

31 March 2020

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Anakinra for flares of pyogenic arthritis in PAPA syndrome

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Identifiers

DOI

10.1038/NRENDO.2009.271

1 reference

22 August 2017

1 reference