(Q46678812)

24 December 2017

title

Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt. (English)

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24 December 2017

author

Joachim Størling

1

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24 December 2017

Nils Billestrup

9

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24 December 2017

Thomas Mandrup-Poulsen

10

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24 December 2017

author name string

J Binzer

2

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24 December 2017

A K Andersson

3

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24 December 2017

R A Züllig

4

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24 December 2017

M Tonnesen

5

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24 December 2017

R Lehmann

6

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24 December 2017

G A Spinas

7

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24 December 2017

S Sandler

8

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24 December 2017

publication date

25 August 2005

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24 December 2017

published in

Diabetologia

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24 December 2017

volume

48

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24 December 2017

issue

10

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24 December 2017

page(s)

2039-2050

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24 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-005-1912-2

exact match

0 references

cites work

Role of Akt and c-Jun N-terminal kinase 2 in apoptosis induced by interleukin-4 deprivation

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-005-1912-2

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

21 January 2018

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12 December 2020

Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets

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12 December 2020

Sodium nitroprusside-induced mitochondrial apoptotic events in insulin-secreting RINm5F cells are associated with MAP kinases activation.

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12 December 2020

Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis

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12 December 2020

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

1 reference

12 December 2020

Insulin-like growth factor I reverses interleukin-1beta inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans

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12 December 2020

Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I.

1 reference

12 December 2020

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

1 reference

12 December 2020

Growth factor protection against cytokine-induced apoptosis in neonatal rat islets of Langerhans: role of Fas

1 reference

12 December 2020

Insulin-like growth factor I (IGF-I) delays the onset of diabetes in non-obese diabetic (NOD) mice

1 reference

12 December 2020

IB1 reduces cytokine-induced apoptosis of insulin-secreting cells

1 reference

12 December 2020

Nitric oxide modulates the c-Jun N-terminal kinase/stress-activated protein kinase activity through activating c-Jun N-terminal kinase kinase

1 reference

12 December 2020

Nitric oxide stimulates stress-activated protein kinases in glomerular endothelial and mesangial cells

1 reference

12 December 2020

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

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12 December 2020

Cellular survival: a play in three Akts

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12 December 2020

Activation of p38 mitogen-activated protein kinase by lipopolysaccharide in human neutrophils requires nitric oxide-dependent cGMP accumulation.

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12 December 2020

Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: involvement of phosphatidylinositol 3-kinase.

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12 December 2020

Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes

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12 December 2020

Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases.

1 reference

12 December 2020

Cytokine-induced inhibition of insulin release from mouse pancreatic beta-cells deficient in inducible nitric oxide synthase

1 reference

12 December 2020

Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase.

1 reference

12 December 2020

Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets

1 reference

12 December 2020

Nitric oxide stimulates the stress-activated protein kinase p38 in rat renal mesangial cells.

1 reference

12 December 2020

PKB binding proteins. Getting in on the Akt.

1 reference

12 December 2020

Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.

1 reference

12 December 2020

Is there a role for nitric oxide in beta-cell dysfunction and damage in IDDM?

1 reference

12 December 2020

Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice.

1 reference

12 December 2020

Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis

1 reference

12 December 2020

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

1 reference

12 December 2020

Signal transduction by the JNK group of MAP kinases

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12 December 2020

Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production

1 reference

12 December 2020

Role for c-Jun N-terminal kinase in beta-cell recovery from nitric oxide-mediated damage

1 reference

12 December 2020

The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells

1 reference

12 December 2020

Nitric oxide negatively regulates c-Jun N-terminal kinase/stress-activated protein kinase by means of S-nitrosylation

1 reference

12 December 2020

Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

1 reference

12 December 2020

Successful simultaneous islet-kidney transplantation using a steroid-free immunosuppression: two-year follow-up

1 reference

12 December 2020

Cytokine-mediated down-regulation of the transcription factor cAMP-response element-binding protein in pancreatic beta-cells

1 reference

12 December 2020

The c-Jun N-terminal kinase pathway and apoptotic signaling (review)

1 reference

12 December 2020

Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

1 reference

12 December 2020

Cytokine-induced PGE(2) formation is reduced from iNOS deficient murine islets

1 reference

12 December 2020

Variations in IB1/JIP1 expression regulate susceptibility of beta-cells to cytokine-induced apoptosis irrespective of C-Jun NH2-terminal kinase signaling.

1 reference

12 December 2020

Differential activation of mitogen-activated protein kinases by nitric oxide-related species

1 reference

12 December 2020

Nitric oxide production and Fas surface expression mediate two independent pathways of cytokine-induced murine beta-cell damage

1 reference

12 December 2020

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

1 reference

12 December 2020

Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

1 reference

12 December 2020

Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1.

1 reference

12 December 2020

Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells.

1 reference

12 December 2020

Overexpression of protein kinase C isoforms protects RAW 264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways

1 reference

12 December 2020

10.1007/S00125-005-1912-2

Identifiers

DOI

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24 December 2017

PubMed ID

16132952

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24 December 2017