(Q35180189)

7 August 2017

title

Study on the pharmacokinetics and metabolism of costunolide and dehydrocostus lactone in rats by HPLC-UV and UPLC-Q-TOF/MS. (English)

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7 August 2017

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Zhangxiao Peng

1

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7 August 2017

Yan Wang

2

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7 August 2017

Xue Gu

3

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7 August 2017

Xiaojie Guo

4

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7 August 2017

Chao Yan

5

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7 August 2017

language of work or name

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2 June 2014

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Biomedical Chromatography

7 August 2017

published in

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7 August 2017

volume

28

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7 August 2017

issue

10

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7 August 2017

page(s)

1325-1334

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Strategies for dealing with metabolite elucidation in drug discovery and development

7 August 2017

cites work

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A sesquiterpene lactone, costunolide, interacts with microtubule protein and inhibits the growth of MCF-7 cells

21 January 2018

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The pharmacokinetics and metabolism of ivermectin in domestic animal species.

21 January 2018

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Increasing throughput and information content for in vitro drug metabolism experiments using ultra-performance liquid chromatography coupled to a quadrupole time-of-flight mass spectrometer

21 January 2018

1 reference

Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells

21 January 2018

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Inhibitory effects of costunolide on the telomerase activity in human breast carcinoma cells

21 January 2018

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Quantitative analysis of costunolide and dehydrocostuslactone in rat plasma by ultraperformance liquid chromatography–electrospray ionization–mass spectrometry

21 January 2018

1 reference

Synergistic antimycobacterial activities of sesquiterpene lactones from Laurus spp.

21 January 2018

1 reference

UPLC-QTOF/MS-based screening and identification of the constituents and their metabolites in rat plasma and urine after oral administration of Glechoma longituba extract

21 January 2018

1 reference

Syringin 4-O-beta-glucoside, a new phenylpropanoid glycoside, and costunolide, a nitric oxide synthase inhibitor, from the stem bark of Magnolia sieboldii.

21 January 2018

1 reference

A new sesquiterpene lactone from the roots of Saussurea lappa: structure-anticancer activity study

21 January 2018

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Synthesis of 13-amino costunolide derivatives as anticancer agents

21 January 2018

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Sesquiterpenoid derivatives from Gonospermum elegans and their cytotoxic activity for HL-60 human promyelocytic cells.

21 January 2018

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Sesquiterpene lactones from Gonospermum gomerae and G. fruticosum and their cytotoxic activities

21 January 2018

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Fungicidal activity of natural and synthetic sesquiterpene lactone analogs

21 January 2018

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Statistical moments in pharmacokinetics.

21 January 2018

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Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BMC.3167

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7 August 2017

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