(Q35181671)

7 August 2017

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title

Integrins, cations and ligands: making the connection (English)

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7 August 2017

Xiong JP

1

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7 August 2017

Stehle T

series ordinal

2

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7 August 2017

Goodman SL

series ordinal

3

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7 August 2017

Arnaout MA

series ordinal

4

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7 August 2017

publication date

1 July 2003

1 reference

Journal of Thrombosis and Haemostasis

7 August 2017

published in

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7 August 2017

volume

1

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7 August 2017

issue

7

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7 August 2017

page(s)

1642-1654

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Integrins: bidirectional, allosteric signaling machines

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Ligand binding to integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Inside-out integrin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Regulation of leukocyte integrin function: affinity vs. avidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Stat1 depends on transcriptional synergy with Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Integrins: versatility, modulation, and signaling in cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Integrin structure: new twists and turns in dynamic cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Transmembrane-truncated alphavbeta3 integrin retains high affinity for ligand binding: evidence for an 'inside-out' suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Domains in plexins: links to integrins and transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Structural basis of collagen recognition by integrin alpha2beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

A graphics model building and refinement system for macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Integrin cytoplasmic domains mediate inside-out signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Regulation of alpha 2 beta 1-mediated fibroblast migration on type I collagen by shifts in the concentrations of extracellular Mg2+ and Ca2+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

An allosteric Ca2+ binding site on the beta3-integrins that regulates the dissociation rate for RGD ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Defining fibronectin's cell adhesion synergy site by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Agonist-specific structural rearrangements of integrin alpha IIbbeta 3. Confirmation of the bent conformation in platelets at rest and after activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Transmembrane signal transduction of the alpha(IIb)beta(3) integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Kinetic and mechanical basis of rolling through an integrin and novel Ca2+-dependent rolling and Mg2+-dependent firm adhesion modalities for the alpha 4 beta 7-MAdCAM-1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Type A modules: interacting domains found in several non-fibrillar collagens and in other extracellular matrix proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Integrin alphaIIb beta3 reconstituted into lipid bilayers is nonclustered in its activated state but clusters after fibrinogen binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Identifying the putative metal ion-dependent adhesion site in the beta2 (CD18) subunit required for alphaLbeta2 and alphaMbeta2 ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

Peptide ligands can bind to distinct sites in integrin alphaIIbbeta3 and elicit different functional responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1538-7836.2003.00277.X

10.1046/J.1538-7836.2003.00277.X

21 January 2018

Identifiers

DOI

1 reference

7 August 2017

1 reference