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Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
review article
1 reference
stated in
Europe PubMed Central
title
Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
main subject
multiple sclerosis
0 references
lessons learned
1 reference
based on heuristic
inferred from title
author
Daniel Ontaneda
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
author name string
Robert J Fox
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Jeremy Chataway
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
publication date
1 February 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
published in
Lancet Neurology
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
volume
14
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
page(s)
208-223
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
A validation study of multicenter diffusion tensor imaging: reliability of fractional anisotropy and diffusivity values.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Clinical and imaging correlates of the multiple sclerosis impact scale in secondary progressive multiple sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Comparison of fingolimod with interferon beta-1a in relapsing-remitting multiple sclerosis: a randomised extension of the TRANSFORMS study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Glial fibrillary acidic protein: a potential biomarker for progression in multiple sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Integration of cognitive impairment in the expanded disability status scale of 215 patients with multiple sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Measuring myelin repair and axonal loss with diffusion tensor imaging.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Macular volume determined by optical coherence tomography as a measure of neuronal loss in multiple sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Sensitivity of conventional memory tests in multiple sclerosis: comparing the Rao Brief Repeatable Neuropsychological Battery and the Minimal Assessment of Cognitive Function in MS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Grey matter magnetization transfer ratio independently correlates with neurological deficit in secondary progressive multiple sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Should SDMT substitute for PASAT in MSFC? A 5-year longitudinal study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Repeated assessment of neuropsychological deficits in multiple sclerosis using the Symbol Digit Modalities Test and the MS Neuropsychological Screening Questionnaire.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Cortical atrophy is relevant in multiple sclerosis at clinical onset.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Interferon beta-1b in secondary progressive MS: results from a 3-year controlled study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Intravenous immunoglobulin in secondary progressive multiple sclerosis: randomised placebo-controlled trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Outcome measures for multiple sclerosis clinical trials: relative measurement precision of the Expanded Disability Status Scale and Multiple Sclerosis Functional Composite.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Correlations between multiple sclerosis functional composite, expanded disability status scale and health-related quality of life during and after treatment of relapses in patients with multiple sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Subpial demyelination in the cerebral cortex of multiple sclerosis patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Benefit of interferon beta-1a on MSFC progression in secondary progressive MS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Markers for different glial cell responses in multiple sclerosis: clinical and pathological correlations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Concurrent validity of the MS Functional Composite using MRI as a biological disease marker.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
The Mayo Clinic-Canadian Cooperative trial of sulfasalazine in active multiple sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Outcomes assessment in multiple sclerosis clinical trials: a critical analysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
The Brief Repeatable Battery of Neuropsychological Tests for Multiple Sclerosis: a preliminary serial study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Cladribine in treatment of chronic progressive multiple sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
Clinical and psychometrical study of a patient with memory disturbances
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
27 September 2018
A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
15 November 2018
Comorbidity, socioeconomic status and multiple sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
15 November 2018
Responsiveness and predictive value of EDSS and MSFC in primary progressive MS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
15 November 2018
Brain atrophy and lesion load in a large population of patients with multiple sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
15 November 2018
Pathological study of spinal cord atrophy in multiple sclerosis suggests limited role of local lesions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4361791
retrieved
15 November 2018
Pathological mechanisms in progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and toxicity of cyclosporine in chronic progressive multiple sclerosis: a randomized, double-blinded, placebo-controlled clinical trial. The Multiple Sclerosis Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linomide in relapsing and secondary progressive MS: part I: trial design and clinical results. North American Linomide Investigators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cladribine and progressive MS: Clinical and MRI outcomes of a multicenter controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Randomized controlled trial of interferon- beta-1a in secondary progressive MS: Clinical results
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intravenous immunoglobulin in primary and secondary chronic progressive multiple sclerosis: a randomized placebo controlled multicentre study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic progressive multiple sclerosis: double-blind controlled study of plasmapheresis in patients taking immunosuppressive drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of total lymphoid irradiation in chronic progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Systemic lymphoblastoid interferon therapy in chronic progressive multiple sclerosis. I. Clinical and MRI evaluation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A placebo-controlled, double-blind, randomized, two-center, pilot trial of Cop 1 in chronic progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Total lymphoid irradiation in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A placebo-controlled trial of isoprinosine in patients with multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low-dose (7.5 mg) oral methotrexate reduces the rate of progression in chronic progressive multiple sclerosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double-blind, placebo-controlled, randomized, crossover trial of high-dose methylprednisolone in patients with chronic progressive form of multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment of secondary progressive multiple sclerosis with the immunomodulator linomide: a double-blind, placebo-controlled pilot study with monthly magnetic resonance imaging evaluation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modified total lymphoid irradiation and low dose corticosteroids in progressive multiple sclerosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase II study of i.v. methylprednisolone in secondary-progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon beta-1a in primary progressive MS: an exploratory, randomized, controlled trial.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A double-blind, randomized, controlled study of oral pirfenidone for treatment of secondary progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single-center, randomized, double-blind, placebo-controlled study of interferon beta-1b on primary progressive and transitional multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase 2, 24-week, randomized, placebo-controlled, double-blind study examining the efficacy and safety of an anti-interleukin-12 and -23 monoclonal antibody in patients with relapsing-remitting or secondary progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Masitinib treatment in patients with progressive multiple sclerosis: a randomized pilot study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of fluoxetine on progression in progressive multiple sclerosis: a double-blind, randomized, placebo-controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
One-year brain atrophy evident in healthy aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Final analysis of the European multicenter trial on IFNbeta-1b in secondary-progressive MS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon β for secondary progressive multiple sclerosis: a systematic review
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adaptive group sequential designs for clinical trials: combining the advantages of adaptive and of classical group sequential approaches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kurtzke scales revisited: the application of psychometric methods to clinical intuition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical significance of the multiple sclerosis functional composite: relationship to patient-reported quality of life
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assessing disability progression with the Multiple Sclerosis Functional Composite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The longitudinal relationship between the patient-reported Multiple Sclerosis Impact Scale and the clinician-assessed Multiple Sclerosis Functional Composite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between brain atrophy and disability: an 8-year follow-up study of multiple sclerosis patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical consequences of MRI activity in treated multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Optimal reference population for the multiple sclerosis functional composite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical impact of 20% worsening on Timed 25-foot Walk and 9-hole Peg Test in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contrast letter acuity as a visual component for the Multiple Sclerosis Functional Composite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Valuation of EuroQOL (EQ-5D) Health States in an Adult US Sample
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MOS 36-ltem Short-Form Health Survey (SF-36)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brain atrophy in relapsing multiple sclerosis: relationship to relapses, EDSS, and treatment with interferon beta-1a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gray matter atrophy is related to long-term disability in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Neocortical Volume Changes With Cognitive Deterioration in Relapsing-Remitting Multiple Sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A magnetization transfer histogram study of normal-appearing brain tissue in MS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Short-term evolution of spinal cord damage in multiple sclerosis: a diffusion tensor MRI study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than peripapillary retinal nerve fiber layer thickness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assessing tissue damage in multiple sclerosis: a biomarker approach
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurofilament light protein and glial fibrillary acidic protein as biological markers in MS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comparative study of CSF neurofilament light and heavy chain protein in MS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heightened intrathecal release of axonal cytoskeletal proteins in multiple sclerosis is associated with progressive disease and clinical disability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970264-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Canadian cooperative trial of cyclophosphamide and plasma exchange in progressive multiple sclerosis. The Canadian Cooperative Multiple Sclerosis Study Group
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25772899
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Randomized, comparative study of interferon beta-1a treatment regimens in MS: The EVIDENCE Trial
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25772899
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Double-masked trial of azathioprine in multiple sclerosis. British and Dutch Multiple Sclerosis Azathioprine Trial Group
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25772899
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25772899
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/S1474-4422(14)70264-9
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PMC publication ID
4361791
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PubMed publication ID
25772899
1 reference
stated in
Europe PubMed Central
PMC publication ID
4361791
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25772899%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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