(Q35183950)

7 August 2017

title

β cell death and dysfunction during type 1 diabetes development in at-risk individuals (English)

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7 August 2017

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1 reference

2

Sahar Usmani-Brown

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Michel Ledizet

7

object named as

Michel Ledizet

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Melena D Bellin

6

object named as

Melena D Bellin

1 reference

7 August 2017

9

Jeffrey P Krischer

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7 August 2017

1

Kevan C Herold

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7 August 2017

8

Jay M Sosenko

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Type 1 Diabetes TrialNet Study Group

7 August 2017

11

object named as

Type 1 Diabetes TrialNet Study Group

1 reference

7 August 2017

10

Jerry P Palmer

1 reference

7 August 2017

Tara Ghazi

3

1 reference

7 August 2017

Jasmin Lebastchi

4

1 reference

7 August 2017

Craig A Beam

5

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7 August 2017

language of work or name

English

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publication date

2 February 2015

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Journal of Clinical Investigation

7 August 2017

published in

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7 August 2017

volume

125

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7 August 2017

issue

3

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7 August 2017

page(s)

1163-1173

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Analysis of β-cell death in type 1 diabetes by droplet digital PCR.

7 August 2017

cites work

1 reference

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Tissue-specific methylation of human insulin gene and PCR assay for monitoring beta cell death.

13 July 2018

1 reference

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Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial

13 July 2018

1 reference

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Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders

13 July 2018

1 reference

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Type 1 diabetes: translating mechanistic observations into effective clinical outcomes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Immune therapy and β-cell death in type 1 diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

The metabolic progression to type 1 diabetes as indicated by serial oral glucose tolerance testing in the Diabetes Prevention Trial-type 1.

13 July 2018

1 reference

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Detection of β cell death in diabetes using differentially methylated circulating DNA.

13 July 2018

1 reference

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Development of autoantibodies in the TrialNet Natural History Study

13 July 2018

1 reference

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Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial

13 July 2018

1 reference

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Influence of microenvironment on engraftment of transplanted β-cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Prognostic performance of metabolic indexes in predicting onset of type 1 diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Genetics, pathogenesis and clinical interventions in type 1 diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1.

13 July 2018

1 reference

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Glucose and C-peptide changes in the perionset period of type 1 diabetes in the Diabetes Prevention Trial-Type 1.

13 July 2018

1 reference

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Prevention of type 1 diabetes: the time has come.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Type 1 diabetes as a relapsing-remitting disease?

13 July 2018

1 reference

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Natural history of beta-cell function in type 1 diabetes

13 July 2018

1 reference

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

13 July 2018

1 reference

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A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

13 July 2018

1 reference

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Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

13 July 2018

1 reference

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

13 July 2018

1 reference

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Phasic insulin release and metabolic regulation in type 2 diabetes.

13 July 2018

1 reference

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Rapid clearance of fetal DNA from maternal plasma

13 July 2018

1 reference

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The role of interleukin-1 in the pathogenesis of IDDM.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Type I diabetes mellitus. A chronic autoimmune disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients

13 July 2018

1 reference

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Quantitative study of insulin secretion and clearance in normal and obese subjects

13 July 2018

1 reference

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Reversal of beta-cell suppression in vitro in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus

13 July 2018

1 reference

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Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Relationships Between Fasting Plasma Glucose Levels and Insulin Secretion During Intravenous Glucose Tolerance Tests

13 July 2018

1 reference

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Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Increasing the accuracy of oral glucose tolerance testing and extending its application to individuals with normal glucose tolerance for the prediction of type 1 diabetes: the Diabetes Prevention Trial-Type 1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial-Type 1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Insulin secretion in type 1 diabetes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4362259

Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation

15 November 2018

1 reference

12 December 2020

Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans

1 reference

12 December 2020

Cytotoxic effects of cytokines on islet beta-cells: evidence for involvement of eicosanoids

1 reference

12 December 2020

Cytotoxic effects of cytokines on human pancreatic islet cells in monolayer culture

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI78142

1 reference

7 August 2017

1 reference

7 August 2017

1 reference