(Q35188535)

7 August 2017

Translocation channel gating kinetics balances protein translocation efficiency with signal sequence recognition fidelity (English)

1 reference

7 August 2017

Steven F Trueman

1

1 reference

PubMed ID

21737680

7 August 2017

Elisabet C Mandon

series ordinal

2

1 reference

PubMed ID

21737680

7 August 2017

Reid Gilmore

series ordinal

3

1 reference

7 August 2017

7 July 2011

1 reference

Molecular Biology of the Cell

7 August 2017

1 reference

7 August 2017

22

1 reference

7 August 2017

17

1 reference

7 August 2017

2983-2993

1 reference

Dynamics of SecY translocons with translocation-defective mutations

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Translocation of proteins through the Sec61 and SecYEG channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

The lateral gate of SecYEG opens during protein translocation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Conformational transition of Sec machinery inferred from bacterial SecYE structures

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Single Copies of Sec61 and TRAP Associate with a Nontranslating Mammalian Ribosome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Ribosome binding of a single copy of the SecY complex: implications for protein translocation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Modeling the effects of prl mutations on the Escherichia coli SecY complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Recognition of a subset of signal sequences by Ssh1p, a Sec61p-related protein in the membrane of endoplasmic reticulum of yeast Saccharomyces cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Multifaceted physiological response allows yeast to adapt to the loss of the signal recognition particle-dependent protein-targeting pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Elongation arrest is a physiologically important function of signal recognition particle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Signal sequence recognition in posttranslational protein transport across the yeast ER membrane.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing the SecA-SecY interaction during the initiation of translocation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Molecular architecture of the ER translocase probed by chemical crosslinking of Sss1p to complementary fragments of Sec61p

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Determination of the transmembrane topology of yeast Sec61p, an essential component of the endoplasmic reticulum translocation complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Signal sequences specify the targeting route to the endoplasmic reticulum membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

The yeast SSS1 gene is essential for secretory protein translocation and encodes a conserved protein of the endoplasmic reticulum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Continued functioning of the secretory pathway is essential for ribosome synthesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Ubiquitin-assisted dissection of protein transport across membranes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

SSS1 encodes a stabilizing component of the Sec61 subcomplex of the yeast protein translocation apparatus.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Proper interaction between at least two components is required for efficient export of proteins to the Escherichia coli cell envelope

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Distinct mutation sites in prlA suppressor mutant strains of Escherichia coli respond either to suppression of signal peptide mutations or to blockage of staphylokinase processing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Getting started with yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

The signal recognition particle in S. cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Signal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Protein translocation across the bacterial cytoplasmic membrane.

28 July 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E11-01-0070

The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E11-01-0070

An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E11-01-0070

X-ray structure of a protein-conducting channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E11-01-0070

Structure of a complex of the ATPase SecA and the protein-translocation channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E11-01-0070

Mutations in the Sec61p Channel Affecting Signal Sequence Recognition and Membrane Protein Topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E11-01-0070

Structural determinants of lateral gate opening in the protein translocon

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164448

Slow translocon gating causes cytosolic exposure of transmembrane and lumenal domains during membrane protein integration

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21737680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The F286Y mutation of PrlA4 tempers the signal sequence suppressor phenotype by reducing the SecA binding affinity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21737680

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E11-01-0070

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

PubMed ID

21737680