(Q35202670)

7 August 2017

Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene (English)

1 reference

Runt-related transcription factor 1

7 August 2017

0 references

1 reference

GOA release 2020-03-11

Transcription factor AP4

1 reference

GOA release 2020-03-11

2

Dan R Littman

1 reference

7 August 2017

Takeshi Egawa

1

1 reference

PubMed ID

21873191

7 August 2017

language of work or name

English

0 references

publication date

22 August 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

1 reference

7 August 2017

108

1 reference

7 August 2017

14873-14878

1 reference

7 August 2017

36

1 reference

ThPOK derepression is required for robust CD8 T cell responses to viral infection

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Thymic emigration revisited

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Transcriptional repression of human immunodeficiency virus type 1 by AP-4

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

E2A proteins enforce a proliferation checkpoint in developing thymocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Plat-E: an efficient and stable system for transient packaging of retroviruses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169121

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

13 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1112293108

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1112293108

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1112293108

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21873191

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21873191

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1112293108

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference

PubMed ID

21873191