(Q35202915)

7 August 2017

Inhibition of glutathione synthesis augments lysis of murine tumor cells by sulfhydryl-reactive antineoplastics (English)

1 reference

7 August 2017

1 reference

2

C F Nathan

1 reference

7 August 2017

B A Arrick

1

1 reference

PubMed ID

6401768

7 August 2017

Z A Cohn

series ordinal

3

1 reference

PubMed ID

6401768

7 August 2017

language of work or name

English

0 references

publication date

1 February 1983

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Journal of Clinical Investigation

7 August 2017

1 reference

7 August 2017

71

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7 August 2017

258-267

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7 August 2017

2

1 reference

Protein measurement with the Folin phenol reagent

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Antitumor effects of hydrogen peroxide in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Reduction in glutathione content of L-PAM resistant L1210 Cells confers drug sensitivity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Glutathione export by human lymphoid cells: depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Reactions of Alpha Methylene Lactone Tumor Inhibitors with Model Biological Nucleophiles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Tumor inhibitors. 69. Structure-cytotoxicity relations among the sesquiterpene lactones

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Novel natural products with antitumor activity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Cytotoxicity of sesquiterpene lactones.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Inhibition of phosphofructokinase by quinone methide and alpha-methylene lactone tumor inhibitors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Sesquiterpene lactones. Part XIII. Cytotoxic activity of eupatolide and eupatoriopicrin on human and animal malignant cells in tissue culture in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Hydrogen peroxide release from mouse peritoneal macrophages: dependence on sequential activation and triggering

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Novel plant-derived tumor inhibitors and their mechanisms of action

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Reduction of glutathione levels in livers of mice treated with N,N?-bis (2-chloroethyl)-N-nitrosourea

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Protection of phagocytic leukocytes by endogenous glutathione: studies in a family with glutathione reductase deficiency

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Sesquiterpene Antitumor Agents: Inhibitors of Cellular Metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

New natural products of interest under development at the National Cancer Institute

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

The Glutathione Status of Cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Recent advances in the chemistry of tumor inhibitors of plant origin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=436864

Inactivation of glycogen synthase by the tumor inhibitor vernolepin

26 September 2018

1 reference

12 December 2020

Reaction of biological thiols with the tumor inhibitor of jatrophone Inhibition of RNA polymerase

1 reference

12 December 2020

Cysteine scavengers. 2. Synthetic alpha-methylenebutyrolactones as potential tumor inhibitors

1 reference

12 December 2020

Selective alkylation: a biomimetic reaction of the antileukemic triptolides?

1 reference

12 December 2020

Tumor inhibitors. 101. Dehydroailanthinone, a new antileukemic quassinoid from Pierreodendron kerstingii

1 reference

12 December 2020

Antitumor Agents XXVII: Effects of Helenalin on Anaerobic and Aerobic Metabolism of Ehrlich Ascites Cells

1 reference

12 December 2020

Protective role of the glutathione redox cycle against adriamycin-mediated toxicity in isolated hepatocytes

1 reference

12 December 2020

Formation of adducts of parthenin and related sesquiterpene lactones with cysteine and glutathione

1 reference

12 December 2020

The effect of doxorubicin on hepatic and cardiac glutathione

1 reference

12 December 2020

Regulatory role of glutathione and soluble sulfhydryl groups in the toxicity of adriamycin

1 reference

12 December 2020

Inhibition of DNA biosynthesis in HeLa cells by cytotoxic and antitumor sesquiterpene lactones

1 reference

12 December 2020

Radiation survival of glutathione-deficient human fibroblasts in culture

1 reference

12 December 2020

Glutathione turnover in human erythrocytes. Inhibition by buthionine sulfoximine and incorporation of glycine by exchange

1 reference

12 December 2020

Role of glutathione in the metabolism-dependent toxicity and chemotherapy of cyclophosphamide

1 reference

12 December 2020

Glutathione depletion sensitizes tumor cells to oxidative cytolysis

1 reference

12 December 2020

9 Depletion of glutathione by inhibition of biosynthesis

1 reference

12 December 2020

Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis

1 reference

12 December 2020

TUMOUR SULPHYDRYL LEVELS AND SENSITIVITY TO THE NITROGEN MUSTARD MEROPHAN

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Toxic effect of alantolactone and dihydroalantolactone in in vitro cultures of leukocytes

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI110766

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

PubMed ID

6401768