(Q35203194)

7 August 2017

1 reference

title

Therapeutic gene silencing in the nervous system (English)

1 reference

7 August 2017

0 references

Matthew J A Wood

1

1 reference

7 August 2017

Barbara Trülzsch

series ordinal

2

1 reference

7 August 2017

Amr Abdelgany

series ordinal

3

1 reference

7 August 2017

David Beeson

series ordinal

4

1 reference

7 August 2017

publication date

19 August 2003

1 reference

7 August 2017

published in

Human Molecular Genetics

1 reference

7 August 2017

volume

12 Spec No 2

1 reference

7 August 2017

page(s)

R279-84

1 reference

Therapeutic Gene Transfer to the Nervous System Using Viral Vectors

7 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Antisense therapeutics: is it as simple as complementary base recognition?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

A DNA enzyme that cleaves RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Gene silencing in mammals by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Retroviral delivery of small interfering RNA into primary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Hippocratic or hypocritic: birth pangs of an ethical code.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

siRNA-mediated gene silencing in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Genomewide view of gene silencing by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Specificity of short interfering RNA determined through gene expression signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Specific interference with gene expression and gene function mediated by long dsRNA in neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

RNAi functions in cultured mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Efficient and specific down-regulation of prion protein expression by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2X3 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Allele-specific silencing of dominant disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Validation in mesenchymal progenitor cells of a mutation-independent ex vivo approach to gene therapy for osteogenesis imperfecta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Hammerhead ribozymes reduce central nervous system (CNS)-derived neuronal nitric oxide synthase messenger RNA in a human cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

bcl-2 Antisense treatment prevents induction of tolerance to focal ischemia in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Combination of endostatin and a protein kinase Calpha DNA enzyme improves the survival of rats with malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Emerging developments in RNA therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Numerous microRNPs in neuronal cells containing novel microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Protein synthesis at synaptic sites on dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Axonal and presynaptic protein synthesis: new insights into the biology of the neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Immune responses to adenovirus vectors in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Immunology of viral-vector-mediated gene transfer into the brain: an evolutionary and developmental perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Intrastriatal and intraventricular injections of oligodeoxynucleotides in the rat brain: tissue penetration, intracellular distribution and c-fos antisense effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDG275

21 January 2018

Identifiers

DOI

10.1093/HMG/DDG275

1 reference

7 August 2017

1 reference