(Q35206929)

7 August 2017

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title

Novel therapeutic strategies based on toll-like receptor signaling (English)

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7 August 2017

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Jeffrey A Lawton

1

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7 August 2017

Partho Ghosh

series ordinal

2

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7 August 2017

publication date

1 August 2003

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Current Opinion in Chemical Biology

7 August 2017

published in

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7 August 2017

volume

7

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7 August 2017

issue

4

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7 August 2017

page(s)

446-451

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Toll-like receptors as potential therapeutic targets for multiple diseases

7 August 2017

cites work

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https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Reciprocal control of T helper cell and dendritic cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Toll-like receptors control activation of adaptive immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Pathogenesis of sepsis: new concepts and implications for future treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Anti-CD14 mAb treatment provides therapeutic benefit after in vivo exposure to endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Effect of anti-CD14 monoclonal antibody on clearance of Escherichia coli bacteremia and endotoxemia

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

IC14, a CD14 specific monoclonal antibody, is a potential treatment for patients with severe sepsis

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Blocking of responses to endotoxin by E5564 in healthy volunteers with experimental endotoxemia

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Interleukin 6 plays a key role in the development of antigen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Divergent therapeutic and immunologic effects of oligodeoxynucleotides with distinct CpG motifs.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

The novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-gamma-producing cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Suppression of allergic reaction by lambda-carrageenan: toll-like receptor 4/MyD88-dependent and -independent modulation of immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

Biological activity of immunostimulatory CpG DNA motifs in domestic animals

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

CpG Oligodeoxynucleotides Protect Normal and SIV-Infected Macaques from Leishmania Infection

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900077-2

7 January 2021

10.1016/S1367-5931(03)00077-2

Identifiers

DOI

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7 August 2017

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