(Q35207843)

7 August 2017

title

2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site (English)

1 reference

7 August 2017

1 reference

4

Folkman J

1 reference

7 August 2017

D'Amato RJ

1

1 reference

7 August 2017

Lin CM

series ordinal

2

1 reference

7 August 2017

Flynn E

series ordinal

3

1 reference

7 August 2017

Hamel E

series ordinal

5

1 reference

7 August 2017

language of work or name

English

0 references

publication date

1 April 1994

1 reference

7 August 2017

number of pages

5

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

7 August 2017

volume

91

1 reference

7 August 2017

issue

9

1 reference

7 August 2017

page(s)

3964-3968

1 reference

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Structural specificity of estrogens in the induction of mitotic chromatid non-disjunction in HeLa cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Diethylstilboestrol: the binding and effects of diethylstilboestrol upon the polymerisation and depolymerisation of purified microtubule protein in vitro.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Estramustine binds MAP-2 to inhibit microtubule assembly in vitro.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Diethylstilbestrol induces metaphase arrest and inhibits microtubule assembly.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

The cytotoxic effects of estradiol-17 beta, catecholestradiols and methoxyestradiols on dividing MCF-7 and HeLa cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Synthesis of alkoxy-substituted diaryl compounds and correlation of ring separation with inhibition of tubulin polymerization: differential enhancement of inhibitory effects under suboptimal polymerization reaction conditions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

The excretion of five different 2-hydroxyoestrogen monomethyl ethers in human pregnancy urine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Molecular features of colchicine associated with antimitotic activity and inhibition of tubulin polymerization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Colchicine inhibition of microtubule assembly via copolymer formation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Endogenous inhibitor of colchicine-tubulin binding in rat brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Molecules in mammalian brain that interact with the colchicine site on tubulin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Separation of active tubulin and microtubule-associated proteins by ultracentrifugation and isolation of a component causing the formation of microtubule bundles.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43703

Comparative properties of the catechol estrogens, I: methylation by catechol-O-methyltransferase and binding to cytosol estrogen receptors

26 September 2018

1 reference

12 December 2020

Effects of organic acids on tubulin polymerization and associated guanosine 5'-triphosphate hydrolysis

1 reference

12 December 2020

Concentrations of 2-methoxyoestrogens in human serum measured by a heterologous immunoassay with an 125I-labelled ligand

1 reference

12 December 2020

Interaction of estramustine phosphate with microtubule-associated proteins

1 reference

12 December 2020

Structure-activity relationships of benzimidazole carbamates as inhibitors of mammalian tubulin, in vitro

1 reference

12 December 2020

A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragment

1 reference

12 December 2020

Mitotic inhibition and chromosome displacement induced by estradiol in Chinese hamster cells

1 reference

12 December 2020

Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin

1 reference

12 December 2020

Qualitative study of the interaction mechanism of estrogenic drugs with tubulin

1 reference

12 December 2020

Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimi

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.91.9.3964

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference