(Q35208007)

English

Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing

scientific article published on December 1, 1983

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing (English)

1 reference

Europe PubMed Central

7 August 2017

affinity labels

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

Jerrold M. Olefsky

5

object named as

J M Olefsky

1 reference

Europe PubMed Central

7 August 2017

author name string

P. Berhanu

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

O. G. Kolterman

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

A. Baron

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

P. Tsai

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

D. Brandenburg

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

language of work or name

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publication date

1 December 1983

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Europe PubMed Central

7 August 2017

full work available at URL

http://www.jci.org/articles/view/111160/files/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

https://europepmc.org/articles/PMC437036

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

https://europepmc.org/articles/PMC437036?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6358259

7 October 2023

http://www.jci.org/articles/view/111160/files/pdf

1 reference

10.1172/JCI111160

https://api.crossref.org/works/10.1172/JCI111160

7 October 2023

Journal of Clinical Investigation

1 reference

Europe PubMed Central

7 August 2017

72

1 reference

Europe PubMed Central

7 August 2017

1958-1970

1 reference

Europe PubMed Central

7 August 2017

6

1 reference

Europe PubMed Central

7 August 2017

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Variations of glucose metabolism by fat cells from three adipose depots of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Internalization and molecular processing of insulin receptors in isolated rat adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Internalization and intracellular processing of insulin and insulin receptors in adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Effect of chloroquine on the internalization of 125I-insulin into subcellular fractions of rat liver. Evidence for an effect of chloroquine on Golgi elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Mechanism of the postreceptor defect in insulin action in human obesity. Decrease in glucose transport system activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Characterization of insulin receptor subunits in brain and other tissues by photoaffinity labeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Lysosomal degradation of receptor-bound 125I-labeled insulin by rat adipocytes: its characterization and dissociation from the short-term biologic effects of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin receptor: evidence that it is a protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Commentary. Lysosomotropic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Methods for the determination of adipose cell size in man and animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Inactivation of lysosomal function in normal cultured human fibroblasts by chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Defect in insulin binding to receptors in obese man. Amelioration with calorie restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

The insulin receptor: its role in insulin resistance of obesity and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin induced changes in insulin binding and insulin-sensitivity of adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

The pathogenic role of an insulin-receptor defect in diabetes mellitus of the obese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin Sensitivity and Insulin Binding to Monocytes in Maturity-Onset Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Molecular mechanism of mitogen action: processing of receptor induced by epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Insulin receptor: covalent labeling and identification of subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Decreased insulin binding to adipocytes and circulating monocytes from obese subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Inhibition of proteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A, and Triton WR 1339

1 reference

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28 July 2018

A desensitized state of the beta adrenergic receptor not associated with high-affinity agonist occupancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

28 July 2018

Purification and properties of the human placental insulin receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

26 September 2018

Differences at the Receptor and Postreceptor Levels Between Human Omental and Subcutaneous Adipose Tissue in the Action of Insulin on Lipolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

26 September 2018

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=437036

26 September 2018

Down regulation of insulin receptors in primary cultures of adult rat hepatocytes in monolayer

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stoichiometric binding and regulation of insulin receptors on human diploid fibroblasts using physiologic insulin levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of photoaffinity labeled insulin receptor proteins by linear polyacrylamide gradient gel electrophoresis under non-denaturing conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Covalent linking of photoreactive insulin to adipocytes produces a prolonged signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unimpaired signal transduction by the adipocyte insulin receptor following its partial proteolytic fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholamine-induced desensitization in turkey erythrocytes: cAMP mediated impairment of high affinity agonist binding without alteration in receptor number

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoaffinity labeling of the insulin receptor in H4 hepatoma cells: lack of cellular receptor processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. Comparison to epidermal growth factor-stimulated phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoaffinity labeling of insulin receptors in viable cultured human lymphocytes. Demonstration of receptor shedding and degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct demonstration of insulin receptor internalization. A quantitative electron microscopic study of covalently bound 125I-photoreactive insulin incubated with isolated hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor binding to fat and blood cells and insulin action in fat cells from insulin-dependent diabetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between the insulin-binding capacity of fat cells and the cellular response to insulin. Studies with intact and trypsin-treated fat cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-dependent regulation of the insulin-sensitivity of adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6358259

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI111160

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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