(Q35208827)

7 August 2017

1 reference

title

RAF antisense oligonucleotide as a tumor radiosensitizer (English)

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7 August 2017

Usha Kasid

1

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7 August 2017

Anatoly Dritschilo

series ordinal

2

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7 August 2017

language of work or name

English

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publication date

1 September 2003

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7 August 2017

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7 August 2017

volume

22

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7 August 2017

issue

37

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7 August 2017

page(s)

5876-5884

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206700

7 August 2017

exact match

0 references

cites work

Insulin Activates Nuclear Factor κB in Mammalian Cells through a Raf-1-mediated Pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Phosphorylation of the myosin-binding subunit of myosin phosphatase by Raf-1 and inhibition of phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Untying the regulation of the Raf-1 kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Effective surgical adjuvant therapy for high-risk rectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Phase I evaluation of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C-alpha, in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Delivery of c-myb antisense oligodeoxynucleotides to human neuroblastoma cells via disialoganglioside GD(2)-targeted immunoliposomes: antitumor effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Tumor radioresistance in clinical radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Raf-1 protein kinase activates the NF-kappa B transcription factor by dissociating the cytoplasmic NF-kappa B-I kappa B complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A).

21 January 2018

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PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

21 January 2018

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Protein kinase A as target for novel integrated strategies of cancer therapy.

21 January 2018

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Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Biological consequences of gene regulation after ionizing radiation exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

Ras and Rho GTPases: a family reunion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Smithsonian closure plan under fire

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Regulation of Raf-1 activation and signalling by dephosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Cdc25A phosphatase suppresses apoptosis induced by serum deprivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Antisense raf oligodeoxyribonucleotide is protected by liposomal encapsulation and inhibits Raf-1 protein expression in vitro and in vivo: implication for gene therapy of radioresistant cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Tumor regression by targeted gene delivery to the neovasculature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

The raf oncogene is associated with a radiation-resistant human laryngeal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Activation of Raf by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Cell cycle targets of Ras/Raf signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Elucidating cell signaling mechanisms using antisense technology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Raf-1 activates MAP kinase-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Abrogation of c-Raf expression induces apoptosis in tumor cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

1 reference

7 January 2021

Ionizing radiation stimulates octamer factor DNA binding activity in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Phosphatidylinositol 3-kinase requirement in activation of the ras/C-raf-1/MEK/ERK and p70(s6k) signaling cascade by the insulinomimetic agent vanadyl sulfate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Effects of c-raf-1 and c-myc expression on radiation response in an in vitro model of human small-cell-lung carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells.Miko

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Association of Grb2 with Sos and Ras with Raf-1 upon gamma irradiation of breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206700

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206700

1 reference

Dimensions Publication ID

7 August 2017

1016329018

0 references

1 reference