(Q35209594)

7 August 2017

title

Influence of mild and moderate hepatic impairment on axitinib pharmacokinetics (English)

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7 August 2017

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Michael A Tortorici

1

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7 August 2017

Melvin Toh

2

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7 August 2017

S V Rahavendran

3

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7 August 2017

Robert R Labadie

4

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7 August 2017

Christine W Alvey

5

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7 August 2017

Thomas Marbury

6

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7 August 2017

Ernesto Fuentes

7

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7 August 2017

Matthew Green

8

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7 August 2017

Grace Ni

9

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7 August 2017

Brian Hee

10

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7 August 2017

Yazdi K Pithavala

11

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7 August 2017

language of work or name

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2 July 2010

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Investigational New Drugs

7 August 2017

published in

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7 August 2017

volume

29

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7 August 2017

issue

6

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7 August 2017

page(s)

1370-1380

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https://scigraph.springernature.com/pub.10.1007/s10637-010-9477-4

7 August 2017

exact match

0 references

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Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Hepatic clearance of drugs. III. Additional experimental evidence supporting the "well-stirred" model, using metabolite (MEGX) generated from lidocaine under varying hepatic blood flow rates and linear conditions in the perfused rat liver in situ pr

28 July 2018

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28 July 2018

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Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

28 July 2018

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Protein Binding and Kinetics of Drugs in Liver Diseases

28 July 2018

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Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma

28 July 2018

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Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results

21 January 2018

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Evaluation of the protein binding ratio of drugs by a micro-scale ultracentrifugation method

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10.1007/S10637-010-9477-4

26 September 2018

Identifiers

DOI

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7 August 2017

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7 August 2017

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