(Q35209996)

7 August 2017

title

Design, synthesis and initial biological evaluation of a novel pladienolide analog scaffold (English)

1 reference

7 August 2017

author name string

Mahesh Kumar Gundluru

1

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7 August 2017

Alan Pourpak

2

1 reference

7 August 2017

Xiaoli Cui

3

1 reference

7 August 2017

Stephan W Morris

4

1 reference

7 August 2017

Thomas R Webb

5

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7 August 2017

publication date

1 January 2011

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7 August 2017

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7 August 2017

volume

2

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7 August 2017

issue

9

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7 August 2017

page(s)

904-908

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Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

7 August 2017

cites work

1 reference

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The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region

13 July 2018

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Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing

13 July 2018

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Synthetic mRNA splicing modulator compounds with in vivo antitumor activity

13 July 2018

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Antitumor compounds based on a natural product consensus pharmacophore

13 July 2018

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Synthesis of the macrocyclic core of (-)-pladienolide B.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171832

A synthetic entry to pladienolide B and FD-895

13 July 2018

1 reference

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Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

13 July 2018

1 reference

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Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities

13 July 2018

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Human melanoma cell line UV responses show independency of p53 function.

13 July 2018

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New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171832

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. I. Taxonomy, fermentation, isolation and screening

13 July 2018

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Splicing factor SF3b as a target of the antitumor natural product pladienolide.

21 January 2018

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Catalytic asymmetric dihydroxylation of olefins with reusable OsO(4)(2-) on ion-exchangers: the scope and reactivity using various cooxidants

21 January 2018

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New cross-aldol reactions. Reactions of silyl enol ethers with carbonyl compounds activated by titanium tetrachloride

21 January 2018

1 reference

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Diastereoselection in lewis-Acid-mediated aldol additions.

21 January 2018

1 reference

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Efficient synthesis of 1alpha-fluoro A-ring phosphine oxide, a useful building block for vitamin D analogues, from (S)-carvone via a highly selective palladium-catalyzed isomerization of dieneoxide to dieneol

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1MD00040C

Enantioselective total synthesis of the antitumor macrolide rhizoxin D.

21 January 2018

1 reference

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Mosher ester analysis for the determination of absolute configuration of stereogenic (chiral) carbinol carbons

21 January 2018

1 reference

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Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein

21 January 2018

1 reference

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Efficient total synthesis of sapinofuranone B

26 September 2018

1 reference

12 December 2020

New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465

1 reference

12 December 2020

Total synthesis of the potent antitumor macrolides pladienolide B and D

1 reference

12 December 2020

Stereochemistry of pladienolide B

1 reference

12 December 2020

New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action

1 reference

12 December 2020

Identifiers

DOI

10.1039/C1MD00040C

1 reference

7 August 2017

1 reference

7 August 2017

1 reference