(Q35210975)

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Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome

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Europe PubMed Central

PubMed publication ID

7 August 2017

Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

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author name string

Junko Kobayashi

1

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Europe PubMed Central

PubMed publication ID

7 August 2017

Masashi Yoshida

2

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Europe PubMed Central

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7 August 2017

Suguru Tarui

3

1 reference

Europe PubMed Central

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7 August 2017

Masataka Hirata

4

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Yusuke Nagai

5

1 reference

Europe PubMed Central

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7 August 2017

Shingo Kasahara

6

1 reference

Europe PubMed Central

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7 August 2017

Keiji Naruse

7

1 reference

Europe PubMed Central

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7 August 2017

Hiroshi Ito

8

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Shunji Sano

9

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7 August 2017

Hidemasa Oh

10

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7 August 2017

language of work or name

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22 July 2014

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Europe PubMed Central

PubMed publication ID

7 August 2017

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Europe PubMed Central

PubMed publication ID

7 August 2017

9

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Europe PubMed Central

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7 August 2017

7

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Europe PubMed Central

PubMed publication ID

7 August 2017

e102796

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Europe PubMed Central

PubMed publication ID

7 August 2017

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Creative Commons Attribution 4.0 International

22 July 2014

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April 2022 Public Data File from Crossref

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An induced pluripotent stem cell model of hypoplastic left heart syndrome (HLHS) reveals multiple expression and functional differences in HLHS-derived cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Coordinating tissue interactions: Notch signaling in cardiac development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Derivation of human induced pluripotent stem cells for cardiovascular disease modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Identification of de novo mutations and rare variants in hypoplastic left heart syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Nongenetic method for purifying stem cell-derived cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Signaling pathways controlling second heart field development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

ABCB1 is predominantly expressed in human fetal neural stem/progenitor cells at an early development stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Hypoplastic left heart syndrome links to chromosomes 10q and 6q and is genetically related to bicuspid aortic valve

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Notch1 regulates the fate of cardiac progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Generation of human-induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

The developmental genetics of congenital heart disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Gene regulatory networks in the evolution and development of the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Mutations in NOTCH1 cause aortic valve disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Adult cardiac stem cells are multipotent and support myocardial regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Right ventricle-pulmonary artery shunt in first-stage palliation of hypoplastic left heart syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: associations with atrial septal defect and hypoplastic left heart syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

28 July 2018

Epigenetic signature of early cardiac regulatory genes in native human adipose-derived stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Left ventricular hypoplasia: a spectrum of disease involving the left ventricular outflow tract, aortic valve, and aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Mechanisms of T-box gene function in the developing heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Hand2 function in second heart field progenitors is essential for cardiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Franklin H. Epstein Lecture. Cardiac development and implications for heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Promoter DNA methylation patterns of differentiated cells are largely programmed at the progenitor stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

NKX2.5mutations in patients with congenital heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Transgenic analysis of the atrialnatriuretic factor (ANF) promoter: Nkx2-5 and GATA-4 binding sites are required for atrial specific expression of ANF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106834

26 September 2018

Hypoplastic left heart syndrome

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0102796

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/25050861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/25050861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of age, diagnosis, and previous surgery in children and adults undergoing heart transplantation for congenital heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25050861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cardiac stem cells exhibit mesenchymal features and are maintained through Akt/GSK-3beta signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25050861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0102796

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

2014PLoSO...9j2796K

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

ResearchGate publication ID

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