(Q35212644)

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Antitumour efficacy of MEK inhibitors in human lung cancer cells and their derivatives with acquired resistance to different tyrosine kinase inhibitors

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7 February 2020

Antitumour efficacy of MEK inhibitors in human lung cancer cells and their derivatives with acquired resistance to different tyrosine kinase inhibitors (English)

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7 February 2020

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Floriana Morgillo

1

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7 February 2020

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7 February 2020

Pierre Saintigny

6

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7 February 2020

Raffaele De Palma

7

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7 February 2020

Fortunato Ciardiello

11

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7 February 2020

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T Cascone

2

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7 February 2020

E D'Aiuto

3

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7 February 2020

E Martinelli

4

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7 February 2020

J V Heymach

8

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7 February 2020

L Berrino

9

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7 February 2020

C Tuccillo

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7 February 2020

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12 July 2011

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7 February 2020

British Journal of Cancer

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7 February 2020

105

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7 February 2020

382-392

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7 February 2020

3

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7 February 2020

https://scigraph.springernature.com/pub.10.1038/bjc.2011.244

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Stem cell property epithelial-to-mesenchymal transition is a core transcriptional network for predicting cetuximab (Erbitux™) efficacy in KRAS wild-type tumor cells

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Antitumor activity of bortezomib in human cancer cells with acquired resistance to anti-epidermal growth factor receptor tyrosine kinase inhibitors

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13 July 2018

Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo

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13 July 2018

Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab

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13 July 2018

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13 July 2018

Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance

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13 July 2018

Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines

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13 July 2018

Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in EGFR wild-type cancers

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13 July 2018

Vascular endothelial growth factor receptor-1 contributes to resistance to anti-epidermal growth factor receptor drugs in human cancer cells.

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13 July 2018

Drug development of MET inhibitors: targeting oncogene addiction and expedience

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13 July 2018

Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

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13 July 2018

EGFR antagonists in cancer treatment

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13 July 2018

Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions

1 reference

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13 July 2018

Primary and acquired resistance to anti-EGFR targeted drugs in cancer therapy

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13 July 2018

Expression of snail in pancreatic cancer promotes metastasis and chemoresistance

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13 July 2018

Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma

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13 July 2018

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13 July 2018

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

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13 July 2018

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13 July 2018

Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition

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13 July 2018

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TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer.

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13 July 2018

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26 September 2018

Identifiers

10.1038/BJC.2011.244

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7 February 2020

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7 February 2020

1 reference

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7 February 2020

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