(Q35213325)

7 August 2017

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title

Higher grade transformation of follicular lymphoma: phenotypic tumor progression associated with diverse genetic lesions (English)

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7 August 2017

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1

Izidore S Lossos

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7 August 2017

Ronald Levy

2

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7 August 2017

language of work or name

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1 June 2003

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Seminars in Cancer Biology

7 August 2017

published in

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7 August 2017

volume

13

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7 August 2017

issue

3

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7 August 2017

page(s)

191-202

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World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997.

7 August 2017

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7 January 2021

Follicular lymphoma; a re-evaluation of its position in the scheme of malignant lymphoma, based on a survey of 253 cases

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7 January 2021

The natural history of nodular lymphoma

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7 January 2021

Histological transformation of non-hodgkin's lymphoma.A prospective study

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7 January 2021

Non-hodgkin's lymphoma.A study of the evolution of the disease based upon 92 autopsied cases

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7 January 2021

Histologic conversion in the non-Hodgkin's lymphomas

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7 January 2021

An autopsy study of histologic progression in non-Hodgkin's lymphomas. 192 cases from the National Cancer Institute

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7 January 2021

The natural history of initially untreated low-grade non-Hodgkin's lymphomas

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7 January 2021

Malignant lymphomas of follicular center cell origin in humans. V. Incidence, clinical features, and prognostic implications of transformation of small cleaved cell nodular lymphoma.

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7 January 2021

Follicular lymphoma: prognostic factors for response and survival

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7 January 2021

Follicular low-grade non-Hodgkin's lymphoma: long-term outcome with or without tumor progression

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Incidence, predictive factors, and outcome of lymphoma transformation in follicular lymphoma patients.

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Activation of the c-myc oncogene in a precursor-B-cell blast crisis of follicular lymphoma, presenting as composite lymphoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Evolution of B-cell malignancy: pre-B-cell leukemia resulting from MYC activation in a B-cell neoplasm with a rearranged BCL2 gene

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The biology of chronic myeloid leukemia

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

CML: mechanisms of disease initiation and progression

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

p53, the cellular gatekeeper for growth and division

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma.

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

p53 gene mutations and rearrangements in non-Hodgkin's lymphoma

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The role of c-myc in cellular growth control

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https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Mechanisms of apoptosis by c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

MYC oncogenes and human neoplastic disease

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Translocations involving c-myc and c-myc function

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Sequential bcl-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Increased C-MYC oncogene copy number detected with combined modified comparative genomic hybridization and FISH analysis in a Richter syndrome case with complex karyotype

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Concurrent disruption of cell cycle associated genes in mantle cell lymphoma: a genotypic and phenotypic study of cyclin D1, p16, p15, p53 and pRb.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Loss of p16/INK4A protein expression in non-Hodgkin's lymphomas is a frequent finding associated with tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Involvement of BCL6 in chromosomal aberrations affecting band 3q27 in B-cell non-Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Somatic mutation of the 5' noncoding region of the BCL-6 gene is associated with intraclonal diversity and clonal selection in histological transformation of follicular lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Small deletions occur in highly conserved regions of the LAZ3/BCL6 major translocation cluster in one case of non-Hodgkin's lymphoma without 3q27 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

BCL-6 mRNA expression in higher grade transformation of follicle center lymphoma: correlation with somatic mutations in the 5' regulatory region of the BCL-6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Somatic point mutations in the translocated bcl-2 genes of non-Hodgkin's lymphomas and lymphocytic leukemias: implications for mechanisms of tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Genetic instability is associated with histological transformation of follicle center lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

G protein mechanisms: insights from structural analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Ras genes and acute myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Detection of N-Ras codon 61 mutations in subpopulations of tumor cells in multiple myeloma at presentation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Analysis of RAS oncogene mutations in human lymphoid malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

1 reference

7 January 2021

Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Defining CD95 as a tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Cancer risk and the ATM gene: a continuing debate

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Cancers in 44 families with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Incidence of cancer in 161 families affected by ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Breast and other cancers in families with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Biallelic mutations in the ATM gene in T-prolymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Mantle cell lymphoma is characterized by inactivation of the ATM gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Acquired chromosome 11q deletion involving the ataxia teleangiectasia locus in B-cell non-Hodgkin's lymphoma: correlation with clinicobiologic features

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Molecular characterization of deletion at 11q22.1-23.3 in mantle cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Mutation of the ATM gene is not involved in the pathogenesis of either follicle center lymphoma or its transformation to higher-grade lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Multiple recurrent genomic defects in follicular lymphoma. A possible model for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Copy number gain at 12q12-14 may be important in the transformation from follicular lymphoma to diffuse large B cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The use of real-time quantitative polymerase chain reaction and comparative genomic hybridization to identify amplification of the REL gene in follicular lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Gain of chromosome 7, which marks the progression from indolent to aggressive follicle centre lymphomas, is restricted to the B-lymphoid cell lineage: a study by FISH in combination with morphology and immunocytochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Gain of chromosome 7 marks the progression from indolent to aggressive follicle centre lymphoma and is a common finding in patients with diffuse large B-cell lymphoma: a study by FISH

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Recurring chromosomal abnormalities in non-Hodgkin's lymphoma: biologic and clinical significance

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Trisomy 12 defines a group of CLL with atypical morphology: correlation between cytogenetic, clinical and laboratory features in 544 patients

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Gain of chromosome arm 9p is characteristic of primary mediastinal B-cell lymphoma (MBL): comprehensive molecular cytogenetic analysis and presentation of a novel MBL cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2803%2900015-4

7 January 2021

10.1016/S1044-579X(03)00015-4

Identifiers

DOI

1 reference

7 August 2017

1 reference