(Q35213348)

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The Cdc45·Mcm2-7·GINS protein complex in trypanosomes regulates DNA replication and interacts with two Orc1-like proteins in the origin recognition complex.

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scholarly article

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30 August 2019

The Cdc45·Mcm2-7·GINS protein complex in trypanosomes regulates DNA replication and interacts with two Orc1-like proteins in the origin recognition complex (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21799014%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

DNA replication licensing factor MCM3, putative

1 reference

5 February 2019

DNA replication complex GINS protein PSF3

1 reference

5 February 2019

Orc1-like protein

1 reference

6 February 2019

DNA replication complex GINS protein PSF1

1 reference

6 February 2019

Cell division cycle 45

1 reference

6 February 2019

DNA replication licensing factor MCM5

1 reference

6 February 2019

origin recognition complex subunit 1 (ORC1), putative

1 reference

6 February 2019

DNA replication licensing factor MCM2

1 reference

6 February 2019

dna replication complex gins protein psf2

1 reference

6 February 2019

DNA replication licensing factor MCM6

1 reference

6 February 2019

DNA replication licensing factor MCM4

1 reference

6 February 2019

DNA replication licensing factor MCM7

1 reference

7 February 2019

dna replication complex gins protein sld5

0 references

dna replication complex gins protein sld5

0 references

2

1 reference

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30 August 2019

author name string

Hung Quang Dang

1

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30 August 2019

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28 July 2011

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30 August 2019

Journal of Biological Chemistry

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30 August 2019

286

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30 August 2019

37

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30 August 2019

32424-32435

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21799014%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Structure and function of the GINS complex, a key component of the eukaryotic replisome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

The Mcm complex: unwinding the mechanism of a replicative helicase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

CRK9 contributes to regulation of mitosis and cytokinesis in the procyclic form of Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

The Aurora Kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase transition and cytokinetic initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Trypanosome prereplication machinery contains a single functional orc1/cdc6 protein, which is typical of archaea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

The chromosomal passenger complex and a mitotic kinesin interact with the Tousled-like kinase in trypanosomes to regulate mitosis and cytokinesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

KMP-11, a basal body and flagellar protein, is required for cell division in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Nuclear export signal consensus sequences defined using a localization-based yeast selection system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Interplay between S-cyclin-dependent kinase and Dbf4-dependent kinase in controlling DNA replication through phosphorylation of yeast Mcm4 N-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Trypanosoma brucei RNA binding proteins p34 and p37 mediate NOPP44/46 cellular localization via the exportin 1 nuclear export pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Cell cycle regulation in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

DNA replication in the archaea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Highly efficient tandem affinity purification of trypanosome protein complexes based on a novel epitope combination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Preventing re-replication of chromosomal DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

DNA replication in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Architecture of the Trypanosoma brucei nucleus during interphase and mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

28 July 2018

Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

A PHO80-like cyclin and a B-type cyclin control the cell cycle of the procyclic form of Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

The Trypanosoma brucei cyclin, CYC2, is required for cell cycle progression through G1 phase and for maintenance of procyclic form cell morphology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

Differentiation of Trypanosoma brucei may be stage non-specific and does not require progression of cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

Cdc45: the missing RecJ ortholog in eukaryotes?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

Eukaryotic chromosome DNA replication: where, when, and how?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

The Cdt1 protein is required to license DNA for replication in fission yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

GINS, a central nexus in the archaeal DNA replication fork

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173170

26 September 2018

Cellular substrates of p34cdc2 and its companion cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.240143

21 January 2018

Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/21799014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21799014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdc6/Orc1 from Pyrococcus furiosus may act as the origin recognition protein and Mcm helicase recruiter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21799014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.240143

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21799014%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21799014%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21799014%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

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