(Q35217039)

7 August 2017

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title

Doxorubicin-induced cardiac mitochondrionopathy (English)

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7 August 2017

Kendall B Wallace

1

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7 August 2017

publication date

1 September 2003

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Basic and Clinical Pharmacology and Toxicology

7 August 2017

published in

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7 August 2017

volume

93

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7 August 2017

issue

3

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7 August 2017

page(s)

105-115

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Reactions of Adriamycin with haemoglobin. Superoxide dismutase indirectly inhibits reactions of the Adriamycin semiquinone

7 August 2017

cites work

1 reference

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A digitized-fluorescence-imaging study of mitochondrial Ca2+ increase by doxorubicin in cardiac myocytes

21 January 2018

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Adriamycin: Energy metabolism and mitochondrial oxidations in the heart of treated rabbits

21 January 2018

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Doxorubicin cardiotoxicity. Serial endomyocardial biopsies and systolic time intervals

21 January 2018

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Structure of the adriamycin-cardiolipin complex. Role in mitochondrial toxicity

21 January 2018

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The cardiac contractile function and hemodynamic control in rats after chronic adriamycin treatment.

21 January 2018

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Inhibition and inactivation of NADH-cytochrome c reductase activity of bovine heart submitochondrial particles by the iron(III)-adriamycin complex

21 January 2018

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The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

21 January 2018

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PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

21 January 2018

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Effects of Adriamycin on heart mitochondrial function in rested and exercised rats

21 January 2018

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Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity

21 January 2018

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Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy

21 January 2018

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Protection by schisanhenol against adriamycin toxicity in rat heart mitochondria

21 January 2018

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Oxidative and non-oxidative mechanisms in the inactivation of cardiac mitochondrial electron transport chain components by doxorubicin.

21 January 2018

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21 January 2018

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Influence of ubiquinone on the inhibitory effect of adriamycin on mitochondrial oxidative phosphorylation

21 January 2018

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Effects of adriamycin on respiratory chain activities in mitochondria from rat liver, rat heart and bovine heart. Evidence for a preferential inhibition of complex III and IV.

21 January 2018

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Mechanism of adriamycin cardiotoxicity: evidence for oxidative stress

21 January 2018

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Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

A new class of free radical scavengers reducing adriamycin mitochondrial toxicity

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Carvedilol protects against doxorubicin-induced mitochondrial cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Selective activation of the sodium-independent, cyclosporin A-sensitive calcium pore of cardiac mitochondria by doxorubicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Adriamycin stimulated superoxide formation in submitochondrial particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Interference with calcium-dependent mitochondrial bioenergetics in cardiac myocytes isolated from doxorubicin-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Doxorubicin-induced persistent oxidative stress to cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Influence of dietary manganese and vitamin E on adriamycin toxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

The mitochondrial permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

The interaction of adriamycin with cardiolipin in model and rat liver mitochondrial membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

Histochemical alterations of acute and chronic doxorubicin cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Physicochemical characteristics of ferric adriamycin complexes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Iron(III)-adriamycin and Iron(III)-daunorubicin complexes: physicochemical characteristics, interaction with DNA, and antitumor activity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Effect of adriamycin on electron transport in rat heart, liver, and tumor mitochondria

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Hepatic and cardiac carnitine palmitoyltransferase activity. Effects of adriamycin and galactosamine

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Mitochondrial regulation of superoxide by Ca2+: An alternate mechanism for the cardiotoxicity of doxorubicin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

The relationship between cardiac function and metabolism in acute adriamycin-treated perfused rat hearts studied by 31P and 13C NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

The mitochondrial phosphate carrier reconstituted in liposomes is inhibited by doxorubicin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Adriamycin as an inhibitor of 11β-hydroxylase activity in adrenal cortex mitochondria

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Mitochondrial NADH dehydrogenase-catalyzed oxygen radical production by adriamycin, and the relative inactivity of 5-iminodaunorubicin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Chronic cardiotoxicity of adriamycin studied in a rat model by 31P NMR.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Inactivation of cytochrome c oxidase activity in mitochondrial membranes during redox cycling of doxorubicin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Destruction of phospholipids and respiratory-chain activity in pig-heart submitochondrial particles induced by an adriamycin-iron complex

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Resonance Raman spectroscopic studies of adriamycin and copper(II)-adriamycin and copper(II)-adriamycin-DNA complexes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Rhein enhances the effect of adriamycin on mitochondrial respiration by increasing antibiotic-membrane interaction

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Adriamycin inactivates cytochrome c oxidase by exclusion of the enzyme from its cardiolipin essential environment

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Kinetics of anthracycline antibiotic free radical formation and reductive glycosidase activity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Adriamycin-induced decrease of myocardial contraction reserve in rats treated with dobutamine

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Suppression of doxorubicin cardiotoxicity by overexpression of catalase in the heart of transgenic mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Inhibition of mitochondrial carnitine palmitoyltransferases by adriamycin and adriamycin analogues

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Cardiac energy metabolism at several stages of adriamycin-induced heart failure in rats.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

A clinicopathologic analysis of adriamycin cardiotoxicity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

The mitochondrial permeability transition: from biochemical curiosity to pathophysiological mechanism

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Protection by salvianolic acid A against adriamycin toxicity on rat heart mitochondria

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Further studies on the generation of reactive oxygen species from activated anthracyclines and the relationship to cytotoxic action and cardiotoxic effects

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Production of Hydroxyl Radical by Iron(III)-Anthraquinone Complexes through Self-Reduction and through Reductive Activation by the Xanthine Oxidase/Hypoxanthine System

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Depletion in vitro of mitochondrial glutathione in rat hepatocytes and enhancement of lipid peroxidation by adriamycin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Enhancement of reactive oxygen-dependent mitochondrial membrane lipid peroxidation by the anticancer drug adriamycin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Adriamycin-Fe(3+)-induced inactivation of rat heart mitochondrial creatine kinase: sensitivity to lipid peroxidation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Inhibition of the cardiac mitochondrial calcium pump by adriamycin in vitro

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Inhibition of mitochondrial oxidative phosphorylation by adriamycin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

The effect of doxorubicin on the transport of pyruvate in rat-heart mitochondria

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Are oxygen radicals responsible for the acute cardiotoxicity of doxorubicin?

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Effects of doxorubicin and its aglycone metabolite on calcium sequestration by rabbit heart, liver, and kidney mitochondria

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Adriamycin-induced cardiac damage in the mouse: a small-animal model of cardiotoxicity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Metabolic activation of adriamycin by NADPH-cytochrome P-450 reductase, rat liver and heart microsomes and covalent protein binding of metabolites

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Covalent protein binding of reactive adriamycin metabolites in rat liver and rat heart microsomes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Effect of dextran sulfate on the survival time and mitochondrial function of Adriamycin (doxorubicin)-treated mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration 1Supported in part by NIH Grant HL58016. The manuscript was not subjected to internal Agency review and, thus, the opinions are those of the

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Subcellular effects of adriamycin in the heart: a concise review

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Occurrence of intramitochondrial Ca2+ granules in a hypertrophied heart exposed to adriamycin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Mitochondrial sulfhydryl group modification by adriamycin aglycones

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Inhibition by cyclosporin A and butylated hydroxytoluene of the inner mitochondrial membrane permeability transition induced by adriamycin aglycones

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Oxidation of mitochondrial pyridine nucleotides by aglycone derivatives of adriamycin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Protective effect of endogenous coenzyme Q on both lipid peroxidation and respiratory chain inactivation induced by an adriamycin-iron complex

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Adriamycin-induced oxidation of myoglobin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Stimulation of myoglobin-dependent lipid peroxidation by adriamycin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Radical-driven Fenton reactions: studies with paraquat, adriamycin, and anthraquinone 6-sulfonate and citrate, ATP, ADP, and pyrophosphate iron chelates

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Nonenzymatic oxygen activation and stimulation of lipid peroxidation by doxorubicin-copper

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

Iron-mediated formation of an oxidized adriamycin free radical

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0773.2003.930301.X

7 January 2021

10.1034/J.1600-0773.2003.930301.X

Identifiers

DOI

1 reference

7 August 2017

1 reference