(Q35219977)

7 August 2017

title

Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis (English)

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7 August 2017

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9

Thomas A Wynn

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7 August 2017

Satish K Madala

1

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7 August 2017

John T Pesce

2

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7 August 2017

Thirumalai R Ramalingam

3

1 reference

7 August 2017

Mark S Wilson

4

1 reference

7 August 2017

Samantha Minnicozzi

5

1 reference

7 August 2017

Allen W Cheever

6

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7 August 2017

Robert W Thompson

7

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7 August 2017

Margaret M Mentink-Kane

8

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7 August 2017

language of work or name

English

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publication date

24 February 2010

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7 August 2017

published in

Journal of Immunology

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7 August 2017

volume

184

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7 August 2017

issue

7

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7 August 2017

page(s)

3955-3963

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Matrix metalloproteinases: fold and function of their catalytic domains

7 August 2017

cites work

1 reference

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Inhibiting metalloproteases with PD 166793 in heart failure: impact on cardiac remodeling and beyond.

13 July 2018

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Matrix metalloproteinase 12 accelerates the initiation of atherosclerosis and stimulates the progression of fatty streaks to fibrous plaques in transgenic rabbits.

13 July 2018

1 reference

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Joint diseases and matrix metalloproteinases: a role for MMP-13.

13 July 2018

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Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice

13 July 2018

1 reference

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Essential role of MMP-12 in Fas-induced lung fibrosis

13 July 2018

1 reference

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Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

13 July 2018

1 reference

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Immunopathology of schistosomiasis

13 July 2018

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Matrix metalloproteinases, the pros and cons, in liver fibrosis

13 July 2018

1 reference

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The IL-21 receptor augments Th2 effector function and alternative macrophage activation

13 July 2018

1 reference

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Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Elevated MMP-12 protein levels in induced sputum from patients with COPD.

13 July 2018

1 reference

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Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis

13 July 2018

1 reference

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Treatment of experimental hepatic fibrosis by combinational delivery of urokinase-type plasminogen activator and hepatocyte growth factor genes

13 July 2018

1 reference

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Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification

13 July 2018

1 reference

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Opposing roles for IL-13 and IL-13 receptor alpha 2 in health and disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Immunopathogenesis of schistosomiasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Fibrotic disease and the T(H)1/T(H)2 paradigm

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

13 July 2018

IL-13 effector functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

A targeted mutation at the known collagenase cleavage site in mouse type I collagen impairs tissue remodeling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

The collagen binding domain of gelatinase A modulates degradation of collagen IV by gelatinase B.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175622

Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis

26 September 2018

1 reference

12 December 2020

IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs

1 reference

12 December 2020

Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 responses in tissue repair

1 reference

12 December 2020

Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni

1 reference

12 December 2020

Role of macrophage metalloelastase in gut inflammation

1 reference

12 December 2020

Regulation of hepatic fibrosis and extracellular matrix genes by the th response: new insight into the role of tissue inhibitors of matrix metalloproteinases

1 reference

12 December 2020

Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0903008

1 reference

7 August 2017

1 reference

7 August 2017

1 reference