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Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase.
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Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
title
Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author
Maddy Parsons
series ordinal
4
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Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
David A Calderwood
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5
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Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author name string
Mark A Simpson
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1
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Europe PubMed Central
PMCID
4375489
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
William D Bradley
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2
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Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
David Harburger
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3
1 reference
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Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Anthony J Koleske
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
language of work or name
English
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publication date
18 February 2015
1 reference
stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
published in
Journal of Biological Chemistry
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PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
290
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stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
issue
13
1 reference
stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
8360-8372
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Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4375489/fullTextXML
based on heuristic
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cites work
Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Integrin cytoplasmic tail interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Arg kinase regulates epithelial cell polarity by targeting β1-integrin and small GTPase pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Integrin structure, activation, and interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Discovery and characterization of a cell-permeable, small-molecule c-Abl kinase activator that binds to the myristoyl binding site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Tyrosine phosphorylation of integrin beta3 regulates kindlin-2 binding and integrin activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Regulation of actin polymerization and adhesion-dependent cell edge protrusion by the Abl-related gene (Arg) tyrosine kinase and N-WASp
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
The tail of integrins, talin, and kindlins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Quantification of integrin receptor agonism by fluorescence lifetime imaging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Structural basis of integrin activation by talin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
The Abl-related gene (Arg) requires its F-actin-microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Src kinase activation by direct interaction with the integrin β cytoplasmic domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Two distinct phosphorylation pathways have additive effects on Abl family kinase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Structural basis for the autoinhibition of c-Abl tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
A myristoyl/phosphotyrosine switch regulates c-Abl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Variation on an Src-like theme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Structural determinants of integrin recognition by talin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Essential roles for the Abl and Arg tyrosine kinases in neurulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Integrins regulate the association and phosphorylation of paxillin by c-Abl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
13 July 2018
Use of a chemical genetic technique to identify myosin IIb as a substrate of the Abl-related gene (Arg) tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
26 September 2018
A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
26 September 2018
Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
26 September 2018
Specification of the direction of adhesive signaling by the integrin beta cytoplasmic domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
26 September 2018
On the role of the platelet membrane skeleton in mediating signal transduction. Association of GP IIb-IIIa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with the membrane skeleton.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4375489
retrieved
26 September 2018
Identifiers
DOI
10.1074/JBC.M115.638874
1 reference
stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Fatcat ID
release_lgqn5npxyrf7daasag523ldbwq
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/lgqn5npxyrf7daasag523ldbwq
retrieved
24 November 2022
based on heuristic
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PMCID
4375489
1 reference
stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed ID
25694433
1 reference
stated in
Europe PubMed Central
PMCID
4375489
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25694433%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
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