(Q35227444)

7 August 2017

title

Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia (English)

1 reference

7 August 2017

1 reference

M Neubert

1

1 reference

7 August 2017

D A Ridder

2

1 reference

7 August 2017

P Bargiotas

3

1 reference

7 August 2017

S Akira

4

1 reference

7 August 2017

M Schwaninger

5

1 reference

7 August 2017

publication date

8 April 2011

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Cell Death & Differentiation

7 August 2017

published in

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7 August 2017

volume

18

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7 August 2017

issue

9

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7 August 2017

page(s)

1521-1530

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describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3178433/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/cdd.2011.29

0 references

cites work

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Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion

13 July 2018

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Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling

13 July 2018

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NF-kappaB signaling in cerebral ischemia

13 July 2018

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TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity

13 July 2018

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TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

13 July 2018

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IKK/NF-kappaB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors

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Genetic dissection of glucocorticoid receptor function in the mouse brain

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13 July 2018

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Improving outcome after stroke: overcoming the translational roadblock

13 July 2018

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Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

13 July 2018

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Apoptosis signal-regulating kinase 1 in stress and immune response

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TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

13 July 2018

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Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth

13 July 2018

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The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease

13 July 2018

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NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox

13 July 2018

1 reference

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IKK mediates ischemia-induced neuronal death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Context-specific inhibition of JNKs: overcoming the dilemma of protection and damage

13 July 2018

1 reference

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Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.

13 July 2018

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Tamoxifen, a selective estrogen receptor modulator, reduces ischemic damage caused by middle cerebral artery occlusion in the ovariectomized female rat.

13 July 2018

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A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

13 July 2018

1 reference

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Role of mitogen- and stress-activated kinases in ischemic injury

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Superoxide attenuates macrophage apoptosis by NF-kappa B and AP-1 activation that promotes cyclooxygenase-2 expression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Functional testing in a mouse stroke model induced by occlusion of the distal middle cerebral artery.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Alternate pathways preserve tumor necrosis factor-alpha production after nuclear factor-kappaB inhibition in neonatal cerebral hypoxia-ischemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

AP-1-dependent transcriptional regulation of NADPH oxidase in human aortic smooth muscle cells: role of p22phox subunit.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Essential function for the kinase TAK1 in innate and adaptive immune responses.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

NF-kappaB is activated and promotes cell death in focal cerebral ischemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178433

Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21475303

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDD.2011.29

1 reference

7 August 2017

1 reference

7 August 2017

1 reference