(Q35230688)

7 August 2017

title

Role of cytokines as a double-edged sword in sepsis (English)

1 reference

7 August 2017

0 references

Hina Chaudhry

1

1 reference

7 August 2017

Juhua Zhou

2

1 reference

7 August 2017

Yin Zhong

3

1 reference

7 August 2017

Mir Mustafa Ali

4

1 reference

7 August 2017

Franklin McGuire

5

1 reference

7 August 2017

Prakash S Nagarkatti

6

1 reference

7 August 2017

Mitzi Nagarkatti

7

1 reference

7 August 2017

publication date

1 November 2013

1 reference

7 August 2017

1 reference

7 August 2017

volume

27

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7 August 2017

issue

6

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7 August 2017

page(s)

669-684

1 reference

Therapeutic potential of targeting IL-17 and IL-23 in sepsis

7 August 2017

cites work

1 reference

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27 July 2018

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Procalcitonin and the role of biomarkers in the diagnosis and management of sepsis

27 July 2018

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27 July 2018

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The composition and signaling of the IL-35 receptor are unconventional

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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The role of interferon-γ in the pathogenesis of acute intra-abdominal sepsis

27 July 2018

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Treatment of severe sepsis and septic shock by CHDF using a PMMA membrane hemofilter as a cytokine modulator

27 July 2018

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Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza

27 July 2018

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27 July 2018

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27 July 2018

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Procalcitonin in sepsis and systemic inflammation: a harmful biomarker and a therapeutic target

27 July 2018

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27 July 2018

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Cytokine profile in elderly patients with sepsis

27 July 2018

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Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.

27 July 2018

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Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review.

27 July 2018

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IL-17 receptor signaling is required to control polymicrobial sepsis

27 July 2018

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The burden of sepsis-associated mortality in the United States from 1999 to 2005: an analysis of multiple-cause-of-death data

27 July 2018

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Lactobacillus suntoryeus inhibits pro-inflammatory cytokine expression and TLR-4-linked NF-kappaB activation in experimental colitis

27 July 2018

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27 July 2018

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The IL-17 cytokine family and their role in allergic inflammation

27 July 2018

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Harmful molecular mechanisms in sepsis

27 July 2018

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27 July 2018

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27 July 2018

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Novel cyclohexene derivatives as anti-sepsis agents: synthetic studies and inhibition of NO and cytokine production

27 July 2018

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The inhibitory cytokine IL-35 contributes to regulatory T-cell function

27 July 2018

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Regulation of interferon-gamma during innate and adaptive immune responses

27 July 2018

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IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells

27 July 2018

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Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study

27 July 2018

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Endotoxin and cytokine detection systems as biomarkers for sepsis-induced renal injury

27 July 2018

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Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

27 July 2018

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IL-18 in autoimmunity: review

27 July 2018

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Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease.

27 July 2018

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27 July 2018

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STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice

27 July 2018

1 reference

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Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation

27 July 2018

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Interleukin-18: a novel prognostic cytokine in bacteria-induced sepsis

27 July 2018

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NF-kappa B activation as a pathological mechanism of septic shock and inflammation

27 July 2018

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27 July 2018

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The immunopathogenesis of sepsis in elderly patients

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit

27 July 2018

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27 July 2018

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27 July 2018

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GM-CSF in inflammation and autoimmunity.

27 July 2018

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27 July 2018

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27 July 2018

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Proinflammatory cytokines

27 July 2018

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Anti-inflammatory cytokines

27 July 2018

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Effect of intranasal corticosteroids on release of cytokines and inflammatory mediators

27 July 2018

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The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes.

27 July 2018

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Effect of a chimeric antibody to tumor necrosis factor-alpha on cytokine and physiologic responses in patients with severe sepsis--a randomized, clinical trial.

27 July 2018

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Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.

27 July 2018

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Cell death induction by TNF: a matter of self control

27 July 2018

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Eosinophils and eosinophil-associated cytokines in allergic inflammation

27 July 2018

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A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

27 July 2018

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Antiinflammatory cytokine responses during clinical sepsis and experimental endotoxemia: sequential measurements of plasma soluble interleukin (IL)-1 receptor type II, IL-10, and IL-13.

27 July 2018

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Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130

27 July 2018

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IL-4 and IL-13 receptors: are they one and the same?

27 July 2018

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Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease.

27 July 2018

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

27 July 2018

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The Functional Role of the ELR Motif in CXC Chemokine-mediated Angiogenesis

27 July 2018

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TNF: a brief review with emphasis on its antitumor activity

27 July 2018

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The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome

27 July 2018

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Recombinant interleukin-1 receptor antagonist (IL-1ra): effective therapy against gram-negative sepsis in rats

27 July 2018

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Delayed hypersensitivity: indicator of acquired failure of host defenses in sepsis and trauma

27 July 2018

1 reference

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Usefulness of procalcitonin upon admission to intensive care in the diagnosis and prognosis of sepsis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Analysis of IL-6, IL-10 and IL-17 genetic polymorphisms as risk factors for sepsis development in burned patients.

26 September 2018

1 reference

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Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance

26 September 2018

1 reference

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Association of interleukin 4 -589T/C polymorphism with T(H)1 and T(H)2 bias and sepsis in Chinese major trauma patients

26 September 2018

1 reference

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Early-onset neonatal sepsis: cord blood cytokine levels at diagnosis and during treatment

26 September 2018

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Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis

26 September 2018

1 reference

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Effects of hemoperfusion with an immobilized polymyxin-B fiber column on cytokine plasma levels in patients with abdominal sepsis.

26 September 2018

1 reference

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Unregulated IL-23/IL-17 immune response in autoimmune diseases

26 September 2018

1 reference

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The diagnostic value of serum leptin monitoring and its correlation with tumor necrosis factor-alpha in critically ill patients: a prospective observational study

26 September 2018

1 reference

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IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction

26 September 2018

1 reference

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Transforming growth factor beta-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection

26 September 2018

1 reference

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IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.

26 September 2018

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Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.

26 September 2018

1 reference

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Serial cytokine levels in patients with severe sepsis

26 September 2018

1 reference

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A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis

26 September 2018

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Induction of IL-8 in periodontal ligament cells by H(2)O (2).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Pathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Continuous hemodiafiltration with cytokine-adsorbing hemofilter in the treatment of severe sepsis and septic shock

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Expression of molecular markers in blood of neonatal foals with sepsis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Interleukin-10-1082 promoter polymorphism in association with cytokine production and sepsis susceptibility

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

The "cytokine profile": a code for sepsis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Outcome of Staphylococcus aureus-triggered sepsis and arthritis in IL-4-deficient mice depends on the genetic background of the host.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Prognostic value of MIP-1 alpha, TGF-beta 2, sELAM-1, and sVCAM-1 in patients with gram-positive sepsis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Induction of interleukin-1 and interleukin-1 receptor antagonist

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

IL-13 protects mice from lipopolysaccharide-induced lethal endotoxemia: correlation with down-modulation of TNF-alpha, IFN-gamma, and IL-12 production.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Endogenous interleukin-11 (IL-11) expression is increased and prophylactic use of exogenous IL-11 enhances platelet recovery and improves survival during thrombocytopenia associated with experimental group B streptococcal sepsis in neonatal rats

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Multiplex cytokine profiling in patients with sepsis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4378830

Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis

15 November 2018

1 reference

12 December 2020

The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: the Caerphilly Study

1 reference

12 December 2020

Serum procalcitonin distinguishes CAP due to bacteria, Mycobacterium tuberculosis and PJP

1 reference

12 December 2020

Adverse functions of IL-17A in experimental sepsis

1 reference

12 December 2020

IL-17 stimulates intraperitoneal neutrophil infiltration through the release of GRO alpha chemokine from mesothelial cells

1 reference

12 December 2020

Clinical manifestations but not cytokine profiles differentiate adult-onset Still's disease and sepsis

1 reference

12 December 2020

Severe sepsis induces deficient interferon-gamma and interleukin-12 production, but interleukin-12 therapy improves survival in peritonitis

1 reference

12 December 2020

Protective effect of Ulinastatin against murine models of sepsis: inhibition of TNF-α and IL-6 and augmentation of IL-10 and IL-13

1 reference

12 December 2020

Evidence of enhanced type 2 immune response and impaired upregulation of a type 1 response in frail elderly nursing home residents

1 reference

12 December 2020

Effects of aging on mortality, hypothermia, and cytokine induction in mice with endotoxemia or sepsis

1 reference

12 December 2020

Sepsis after major visceral surgery is associated with sustained and interferon-gamma-resistant defects of monocyte cytokine production

1 reference

12 December 2020

Midkine, a multifunctional cytokine, in patients with severe sepsis and septic shock: a pilot study

1 reference

12 December 2020

Bacterial endotoxin induces STAT3 activation in the mouse brain

1 reference

12 December 2020

Tumor necrosis factor-alpha (TNF-alpha) gene polymorphism in surgical intensive care patients with SIRS

1 reference

12 December 2020

Androstenediol ameliorates alterations in immune cells cytokine production capacity in a two-hit model of trauma-hemorrhage and sepsis

1 reference

12 December 2020

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

1 reference

12 December 2020

[Clinical significance of interleukin-6 (IL-6) as a prognostic factor of cancer disease]

1 reference

12 December 2020

Traffic of leukocytes and cytokine up-regulation in the central nervous system in sepsis

1 reference

12 December 2020

Neutralization of interleukin-10 or transforming growth factor-β decreases the percentages of CD4+ CD25+ Foxp3+ regulatory T cells in septic mice, thereby leading to an improved survival

1 reference

12 December 2020

Neutrophil CD64 expression and serum IL-8: Sensitive early markers of severity and outcome in sepsis

1 reference

12 December 2020

IL-4–induced activation of the Stat6 pathway contributes to the suppression of cell-mediated immunity and death in sepsis

1 reference

12 December 2020

Transforming growth factor-beta negatively modulates T-cell responses in sepsis

1 reference

12 December 2020

Differential effects of IL-17 pathway in disseminated candidiasis and zymosan-induced multiple organ failure

1 reference

12 December 2020

Serum cytokine differences in severely burned children with and without sepsis

1 reference

12 December 2020

[Epidemiology of infection and sepsis in intensive care unit patients]

1 reference

12 December 2020

Orally administered recombinant human interleukin-11 is protective in experimental neutropenic sepsis

1 reference

12 December 2020

Role of Interleukin 6 and Transforming Growth Factor–β in the Induction of Depressed Splenocyte Responses Following Sepsis

1 reference

12 December 2020

In vitro cow's milk protein-specific inflammatory and regulatory cytokine responses in preterm infants with necrotizing enterocolitis and sepsis

1 reference

12 December 2020

Interferon-gamma attenuates hemorrhage-induced suppression of macrophage and splenocyte functions and decreases susceptibility to sepsis

1 reference

12 December 2020

Neutralization of IL-10 restores the downregulation of IL-18 receptor on natural killer cells and interferon-γ production in septic mice, thus leading to an improved survival

1 reference

12 December 2020

[Epidemiology of severe sepsis]

1 reference

12 December 2020

A novel biomarker-guided immunomodulatory approach for the therapy of sepsis

1 reference

12 December 2020

Immune cytokine response in combat casualties: blast or explosive trauma with or without secondary sepsis

1 reference

12 December 2020

The interleukin-6 (IL6)-174 G/C promoter genotype is associated with the presence of septic shock and the ex vivo secretion of IL6

1 reference

12 December 2020

Interferon-gamma 874A>T genetic polymorphism is associated with infectious complications following surgery in patients with thoracic esophageal cancer

1 reference

12 December 2020

IL-8, IL-12 and IL-10 cytokines generation by neutrophils, fibroblasts and neutrophils- fibroblasts interaction in psoriasis

1 reference

12 December 2020

Differential immunostimulating effect of granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF) and interferon gamma (IFNgamma) after severe trauma

1 reference

12 December 2020

Interferon-gamma gene polymorphisms and the development of sepsis in patients with trauma

1 reference

12 December 2020

Splenic Immune Suppression in Sepsis: A Role for IL-10-Induced Changes in P38 MAPK Signaling

1 reference

12 December 2020

Identifiers

PMC publication ID

4378830

1 reference

7 August 2017

1 reference