(Q34468354)

2 August 2017

title

Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation (English)

1 reference

2 August 2017

main subject

protein ubiquitination

1 reference

10

Michael Karin

1 reference

2 August 2017

K Venuprasad

1

1 reference

2 August 2017

Chris Elly

2

1 reference

2 August 2017

Min Gao

3

1 reference

2 August 2017

Shahram Salek-Ardakani

4

1 reference

2 August 2017

Yohsuke Harada

5

1 reference

2 August 2017

Jun-Li Luo

6

1 reference

2 August 2017

Chun Yang

7

1 reference

2 August 2017

Michael Croft

8

1 reference

2 August 2017

Kazushi Inoue

9

1 reference

2 August 2017

Yun-Cai Liu

11

1 reference

2 August 2017

language of work or name

English

0 references

publication date

23 March 2006

1 reference

Journal of Clinical Investigation

2 August 2017

published in

1 reference

2 August 2017

volume

116

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2 August 2017

issue

4

1 reference

2 August 2017

page(s)

1117-1126

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Oral tolerance in the absence of naturally occurring Tregs

2 August 2017

cites work

1 reference

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Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor

6 July 2018

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Tregs and allergic disease

6 July 2018

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Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3.

6 July 2018

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Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

6 July 2018

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Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.

6 July 2018

1 reference

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OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation

6 July 2018

1 reference

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GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells

6 July 2018

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Molecular mechanisms regulating Th1 immune responses

6 July 2018

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6 July 2018

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Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB.

6 July 2018

1 reference

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Asthma: an epidemic of dysregulated immunity

6 July 2018

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Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

6 July 2018

1 reference

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Transcriptional mechanisms underlying lymphocyte tolerance.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

The enemy within: keeping self-reactive T cells at bay in the periphery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Mechanisms underlying ubiquitination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Themes and variations on ubiquitylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Tolerance and autoimmunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

JNK is required for effector T-cell function but not for T-cell activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

"Anergy" of TH0 helper T lymphocytes induces downregulation of TH1 characteristics and a transition to a TH2-like phenotype

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Th2 cell clonal anergy as a consequence of partial activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Lymphocyte responses and cytokines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Transactivation by AP-1 is a molecular target of T cell clonal anergy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Stat signals release activated naive Th cells from an anergic checkpoint

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Signaling through OX40 (CD134) breaks peripheral T-cell tolerance.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Defective transcription of the IL-2 gene is associated with impaired expression of c-Fos, FosB, and JunB in anergic T helper 1 cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1409741

Adjuvant costimulation during secondary antigen challenge directs qualitative aspects of oral tolerance induction, particularly during the neonatal period

9 December 2018

1 reference

12 December 2020

Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation

1 reference

12 December 2020

Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells

1 reference

12 December 2020

Defective T Cell Differentiation in the Absence of Jnk1

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI26858

1 reference

2 August 2017

1 reference

2 August 2017

1 reference