(Q35232747)

7 August 2017

title

On improvement in ejection fraction with iron chelation in thalassemia major and the risk of future heart failure (English)

1 reference

7 August 2017

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1 reference

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D J Pennell

1

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7 August 2017

J P Carpenter

series ordinal

2

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7 August 2017

M Roughton

series ordinal

3

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7 August 2017

Zi Cabantchik

series ordinal

4

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7 August 2017

publication date

12 September 2011

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Journal of Cardiovascular Magnetic Resonance

7 August 2017

published in

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7 August 2017

volume

13

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7 August 2017

page(s)

45

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Creative Commons Attribution 2.0 Generic

7 August 2017

copyright license

start time

12 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Cardiac iron and cardiac disease in males and females with transfusion-dependent thalassemia major: a T2* magnetic resonance imaging study.

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Continued improvement in myocardial T2* over two years of deferasirox therapy in β-thalassemia major patients with cardiac iron overload

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Combined therapy with idebenone and deferiprone in patients with Friedreich's ataxia.

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Optical imaging of mitochondrial function uncovers actively propagating waves of mitochondrial membrane potential collapse across intact heart.

27 July 2018

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27 July 2018

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Effects of deferasirox and deferiprone on cellular iron load in the human hepatoma cell line HepaRG.

27 July 2018

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Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major

27 July 2018

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The efficacy of iron chelator regimes in reducing cardiac and hepatic iron in patients with thalassaemia major: a clinical observational study

27 July 2018

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Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation

27 July 2018

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Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction.

27 July 2018

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A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance

27 July 2018

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Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis

27 July 2018

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27 July 2018

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Downregulation of p38 kinase pathway by cAMP response element-binding protein protects HL-60 cells from iron chelator-induced apoptosis

27 July 2018

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Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: a retrospective analysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Involvement of p38 MAP kinase during iron chelator-mediated apoptotic cell death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Molecular bases of cellular iron toxicity

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Mitochondrial dysfunction in cardiac disease: ischemia--reperfusion, aging, and heart failure

27 July 2018

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Deferoxamine pharmacokinetics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance; are they interchangeable?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Pathophysiology of iron overload.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Iron chelators induce apoptosis in proliferating cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Deferiprone (L1) chelates pathologic iron deposits from membranes of intact thalassemic and sickle red blood cells both in vitro and in vivo.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Energy status of the rapidly paced canine myocardium in congestive heart failure

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Myocardial iron loading in patients with thalassemia major on deferoxamine chelation.

27 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

T2* cardiovascular magnetic resonance in the management of thalassemia patients in Oman.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Efficacy of deferasirox in reducing and preventing cardiac iron overload in beta-thalassemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

A single breath-hold multiecho T2* cardiovascular magnetic resonance technique for diagnosis of myocardial iron overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Normalized Left Ventricular Systolic and Diastolic Function by Steady State Free Precession Cardiovascular Magnetic Resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Improving survival with deferiprone treatment in patients with thalassemia major: a prospective multicenter randomised clinical trial under the auspices of the Italian Society for Thalassemia and Hemoglobinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Value of sequential monitoring of left ventricular ejection fraction in the management of thalassemia major

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Mitochondrial dysfunction may explain the cardiomyopathy of chronic iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Bioenergetic abnormalities associated with severe left ventricular hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Functional and bioenergetic modulations in the infarct border zone following autologous mesenchymal stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Deferiprone chelation therapy for thalassemia major

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Deferasirox decreases age-associated iron accumulation in the aging F344XBN rat heart and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1532-429X-13-45

Deferasirox for up to 3 years leads to continued improvement of myocardial T2* in patients with β-thalassemia major.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Heart mitochondria: gates of life and death

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Heart failure in beta thalassemia: a 5-year follow-up study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180261

Cardiac magnetic resonance in transfusion dependent thalassaemia: assessment of iron load and relationship to left ventricular ejection fraction

26 September 2018

1 reference

12 December 2020

Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy

1 reference

12 December 2020

Adriamycin inactivates cytochrome c oxidase by exclusion of the enzyme from its cardiolipin essential environment

1 reference

12 December 2020

Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells

1 reference

12 December 2020

Deferiprone therapy in homozygous human beta-thalassemia removes erythrocyte membrane free iron and reduces KCl cotransport activity

1 reference

12 December 2020

31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure

1 reference

12 December 2020

31P NMR spectroscopy detects metabolic abnormalities in asymptomatic patients with hypertrophic cardiomyopathy

1 reference

12 December 2020

Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes. Implications for the arrhythmogenesis of human siderotic heart disease

1 reference

12 December 2020

Risk factors for death in patients with beta-thalassemia major: results of a case-control study

1 reference

12 December 2020

Cardiolipin requirement by cytochrome oxidase and the catalytic role of phospholipid

1 reference

12 December 2020

Successful chelation therapy with the combination of deferasirox and deferiprone in a patient with thalassaemia major and persisting severe iron overload after single-agent chelation therapies

1 reference

12 December 2020

Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload

1 reference

12 December 2020

Decreased energy reserve in an animal model of dilated cardiomyopathy. Relationship to contractile performance

1 reference

12 December 2020

Normalized left ventricular volumes and function in thalassemia major patients with normal myocardial iron

1 reference

12 December 2020

Myocardial oxygenation during high work states in hearts with postinfarction remodeling

1 reference

12 December 2020

Identifiers

DOI

10.1186/1532-429X-13-45

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference

7 August 2017

1 reference