(Q35234820)

7 August 2017

title

An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice (English)

1 reference

7 August 2017

1 reference

acute myeloid leukemia

1 reference

Jay L Grisolano

1

1 reference

7 August 2017

Julie O'Neal

series ordinal

2

1 reference

7 August 2017

Jennifer Cain

series ordinal

3

1 reference

7 August 2017

Michael H Tomasson

series ordinal

4

1 reference

7 August 2017

language of work or name

English

0 references

publication date

24 July 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

volume

100

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7 August 2017

issue

16

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7 August 2017

page(s)

9506-9511

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AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

13 July 2018

1 reference

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Chromosome translocations and covert leukemic clones are generated during normal fetal development

13 July 2018

1 reference

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13 July 2018

Role of FLT3 in leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

13 July 2018

1 reference

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Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

13 July 2018

1 reference

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Role of co-repressors in transcriptional repression mediated by the t(8;21), t(16;21), t(12;21), and inv(16) fusion proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

13 July 2018

1 reference

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Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Oligomerization of ETO is obligatory for corepressor interaction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

13 July 2018

1 reference

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Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

13 July 2018

1 reference

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

13 July 2018

1 reference

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Translocation (8;21) in oligoblastic leukemia: is this a true myelodysplastic syndrome?

13 July 2018

1 reference

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t(8;21) myelodysplasia, an early presentation of M2 AML

13 July 2018

1 reference

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Functional domains of the t(8;21) fusion protein, AML-1/ETO.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Detection of specific sequences among DNA fragments separated by gel electrophoresis. 1975.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia

13 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1531730100

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1531730100

Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=170948

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials. MRC Adult Leukaemia Working Party

24 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1531730100

Myelodysplastic syndrome with translocation (8;21): a distinct myelodysplastic syndrome entity or M2-acute myeloid leukemia with extensive myeloid maturation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1531730100

C-kit mutations in core binding factor leukemias

21 January 2018

1 reference

12 December 2020

TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor

1 reference

12 December 2020

Cooperative function of Aml1-ETO corepressor recruitment domains in the expansion of primary bone marrow cells

1 reference

12 December 2020

Correlation between cell morphology and expression of the AML1/ETO chimeric transcript in patients with acute myeloid leukemia without the t(8;21)

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1531730100

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference