(Q35275372)

7 August 2017

title

Heme biosynthesis modulation via δ-aminolevulinic acid administration attenuates chronic hypoxia-induced pulmonary hypertension (English)

1 reference

7 August 2017

1 reference

Raed Alhawaj

1

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7 August 2017

Dhara Patel

2

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7 August 2017

Melissa R Kelly

3

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7 August 2017

Dong Sun

4

1 reference

7 August 2017

Michael S Wolin

5

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7 August 2017

publication date

6 February 2015

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American Journal of Physiology - Lung Cellular and Molecular Physiology

7 August 2017

published in

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7 August 2017

volume

308

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7 August 2017

issue

7

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7 August 2017

page(s)

L719-28

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Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide

7 August 2017

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12 July 2018

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Dehydroepiandrosterone promotes pulmonary artery relaxation by NADPH oxidation-elicited subunit dimerization of protein kinase G 1α.

12 July 2018

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Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension

12 July 2018

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The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress.

12 July 2018

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MicroRNA-210 decreases heme levels by targeting ferrochelatase in cardiomyocytes

12 July 2018

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Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells.

12 July 2018

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Relationships between vascular oxygen sensing mechanisms and hypertensive disease processes

12 July 2018

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NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone

12 July 2018

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A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension

12 July 2018

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High levels of zinc-protoporphyrin identify iron metabolic abnormalities in pulmonary arterial hypertension

12 July 2018

1 reference

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Cinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension

12 July 2018

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Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease

12 July 2018

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Targeting soluble guanylate cyclase for the treatment of pulmonary hypertension.

12 July 2018

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Role for miR-204 in human pulmonary arterial hypertension

12 July 2018

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Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension

12 July 2018

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Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD.

12 July 2018

1 reference

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NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets

12 July 2018

1 reference

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Cellular and molecular basis of pulmonary arterial hypertension

12 July 2018

1 reference

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HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements

12 July 2018

1 reference

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Pulmonary hypertension in COPD.

12 July 2018

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Effects of hypoxia on relationships between cytosolic and mitochondrial NAD(P)H redox and superoxide generation in coronary arterial smooth muscle

12 July 2018

1 reference

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The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Nitric oxide in the pulmonary vasculature

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Regulation of ferrochelatase gene expression by hypoxia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Role of endothelin-1 in lung disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Hypoxic up-regulation of erythroid 5-aminolevulinate synthase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Hemodynamic effects of 5-aminolevulinic acid in humans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4385991

Heme deficiency selectively interrupts assembly of mitochondrial complex IV in human fibroblasts: revelance to aging

26 September 2018

1 reference

12 December 2020

Guanylate cyclase from bovine lung. A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme

1 reference

12 December 2020

Selective accumulation of endogenously produced porphyrins in a liver metastasis model in rats

1 reference

12 December 2020

Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia

1 reference

12 December 2020

Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation

1 reference

12 December 2020

10.1152/AJPLUNG.00155.2014

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

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